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    [{"orgOrder":0,"company":"Advanz Pharma","sponsor":"Nordic Capital","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Small molecule","year":"2021","type":"Acquisition","leadProduct":"Ceftobiprole Medocaril","moa":"PBP2a","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"Advanz Pharma","amount2":0.84999999999999998,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.84999999999999998,"dosageForm":"Powder for Concentrate for Solution for Infusion\n","sponsorNew":"Advanz Pharma \/ Nordic Capital","highestDevelopmentStatusID":"12","companyTruncated":"Advanz Pharma \/ Nordic Capital"},{"orgOrder":0,"company":"Advanz Pharma","sponsor":"Intercept Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Acquisition","leadProduct":"Obeticholic Acid","moa":"Farnesoid X receptor","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Approved","graph3":"Advanz Pharma","amount2":0.45000000000000001,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Hepatology","amount2New":0.45000000000000001,"dosageForm":"Tablet","sponsorNew":"Advanz Pharma \/ Advanz Pharma","highestDevelopmentStatusID":"12","companyTruncated":"Advanz Pharma \/ Advanz Pharma"},{"orgOrder":0,"company":"Advanz Pharma","sponsor":"Intercept Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Divestment","leadProduct":"Obeticholic Acid","moa":"FXR","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Approved","graph3":"Advanz Pharma","amount2":0.45000000000000001,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Hepatology","amount2New":0.45000000000000001,"dosageForm":"Tablet, Film Coated","sponsorNew":"Advanz Pharma \/ Advanz Pharma","highestDevelopmentStatusID":"12","companyTruncated":"Advanz Pharma \/ Advanz Pharma"},{"orgOrder":0,"company":"Advanz Pharma","sponsor":"PolyPid","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"ISRAEL","productType":"Small molecule","year":"2022","type":"Licensing Agreement","leadProduct":"Doxycycline Hyclate","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Advanz Pharma","amount2":0.11,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.11,"dosageForm":"Powder, Extended Release","sponsorNew":"Advanz Pharma \/ ADVANZ PHARMA","highestDevelopmentStatusID":"10","companyTruncated":"Advanz Pharma \/ ADVANZ PHARMA"},{"orgOrder":0,"company":"Advanz Pharma","sponsor":"Applied Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Partnership","leadProduct":"Govorestat","moa":"","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Advanz Pharma","amount2":0.14000000000000001,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0.14000000000000001,"dosageForm":"","sponsorNew":"Advanz Pharma \/ Advanz Pharma","highestDevelopmentStatusID":"10","companyTruncated":"Advanz Pharma \/ Advanz Pharma"},{"orgOrder":0,"company":"Advanz Pharma","sponsor":"Alvotech","pharmaFlowCategory":"D","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"ICELAND","productType":"Large molecule","year":"2023","type":"Agreement","leadProduct":"Omalizumab","moa":"","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase III","graph3":"Advanz Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Advanz Pharma \/ Advanz Pharma","highestDevelopmentStatusID":"10","companyTruncated":"Advanz Pharma \/ Advanz Pharma"},{"orgOrder":0,"company":"Advanz Pharma","sponsor":"Alvotech","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"ICELAND","productType":"Large molecule","year":"2023","type":"Partnership","leadProduct":"Golimumab","moa":"","graph1":"Immunology","graph2":"Phase III","graph3":"Advanz Pharma","amount2":0.34000000000000002,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Immunology","amount2New":0.34000000000000002,"dosageForm":"Injectable\/Injection","sponsorNew":"Advanz Pharma \/ Advanz Pharma","highestDevelopmentStatusID":"10","companyTruncated":"Advanz Pharma \/ Advanz Pharma"},{"orgOrder":0,"company":"Advanz Pharma","sponsor":"UCB Pharma S.A","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"BELGIUM","productType":"Small molecule","year":"2020","type":"Acquisition","leadProduct":"Alprostadil","moa":"","graph1":"Psychiatry\/Psychology","graph2":"Approved","graph3":"Advanz Pharma","amount2":0.10000000000000001,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Psychiatry","amount2New":0.10000000000000001,"dosageForm":"Infusion","sponsorNew":"Advanz Pharma \/ Advanz Pharma","highestDevelopmentStatusID":"12","companyTruncated":"Advanz Pharma \/ Advanz Pharma"},{"orgOrder":0,"company":"Advanz Pharma","sponsor":"Sanofi","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"FRANCE","productType":"Small molecule","year":"2022","type":"Acquisition","leadProduct":"Aztreonam","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"Advanz Pharma","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Advanz Pharma \/ Advanz Pharma","highestDevelopmentStatusID":"12","companyTruncated":"Advanz Pharma \/ Advanz Pharma"},{"orgOrder":0,"company":"Advanz Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"UNITED KINGDOM","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Paliperidone Palmitate","moa":"","graph1":"Psychiatry\/Psychology","graph2":"Approved","graph3":"Advanz Pharma","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Pre-Filled Syringe","sponsorNew":"Advanz Pharma \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Advanz Pharma \/ Not Applicable"},{"orgOrder":0,"company":"Advanz Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Enmetazobactam","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"Advanz Pharma","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Advanz Pharma \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Advanz Pharma \/ Not Applicable"},{"orgOrder":0,"company":"Advanz Pharma","sponsor":"Alvotech","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"ICELAND","productType":"Large molecule","year":"2024","type":"Agreement","leadProduct":"Aflibercept","moa":"","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Advanz Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"","sponsorNew":"Advanz Pharma \/ Advanz Pharma","highestDevelopmentStatusID":"10","companyTruncated":"Advanz Pharma \/ Advanz Pharma"}]

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                            01

                            Advanz Pharma

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                            Lead Product(s) : Aflibercept

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase III

                            Recipient : Alvotech

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Alvotech And Advanz Sign Agreement For Eylea Biosimilar In Europe

                            Details : Under the agreement, Alvotech will develop AVT06 (Aflibercept) biosimilar to Eylea. Advanz Pharma will be responsible for registration and commercializing in Europe, except for Germany and France.

                            Brand Name : AVT06

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            June 19, 2024

                            Lead Product(s) : Aflibercept

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase III

                            Recipient : Alvotech

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            02

                            Advanz Pharma

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                            Lead Product(s) : Enmetazobactam,Cefepime

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            UK MHRA Approves Advanz Pharma Antibiotic for Complex Infections

                            Details : UK MHRA approved Exblifep (cefepime/enmetazobactam) antibiotic which is indicated to treat adults suffering from complicated UTIs and certain kinds of pneumonia acquired during hospital stays.

                            Brand Name : Exblifep

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 05, 2024

                            Lead Product(s) : Enmetazobactam,Cefepime

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Advanz Pharma

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                            Lead Product(s) : Golimumab

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Recipient : Alvotech

                            Deal Size : $343.4 million

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Alvotech and Advanz Pharma Extend Strategic Partnership to Commercialize Five Proposed Biosimilars in Europe

                            Details : Advanz Pharma secures exclusive rights from Alvotech to commercialize AVT05, a biosimilar candidate to Simponi and Simponi Aria (golimumab), AVT16, a proposed biosimilar to Entyvio (vedolizumab), and three additional early-stage, undisclosed biosimilar c...

                            Brand Name : AVT05

                            Molecule Type : Large molecule

                            Upfront Cash : $60.1 million

                            May 24, 2023

                            Lead Product(s) : Golimumab

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Recipient : Alvotech

                            Deal Size : $343.4 million

                            Deal Type : Partnership

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                            04

                            Advanz Pharma

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                            Lead Product(s) : Paliperidone Palmitate

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            ADVANZ PHARMA Launches Palmeux®/Paliperidone 1-month Long-acting Injection Across Various European countries

                            Details : Palmeux (paliperidone palmitate) is a second-generation antipsychotic, also known as an atypical antipsychotic (simultaneous serotonin and dopamine antagonist) for the treatment of schizophrenia in adult patients.

                            Brand Name : Palmeux

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            February 17, 2023

                            Lead Product(s) : Paliperidone Palmitate

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Advanz Pharma

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                            Advanz Pharma

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                            Lead Product(s) : Omalizumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase III

                            Recipient : Alvotech

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Alvotech Enters Into Commercialization Agreement With Advanz Pharma for Proposed Biosimilar to Xolair® (Omali...

                            Details : Under the terms of the agreement, Advanz Pharma will commercialize AVT23, a proposed biosimilar to Xolair® (omalizumab) in the European Economic Area, UK, Switzerland, Canada, Australia, and New Zealand and Alvotech will be responsible for development a...

                            Brand Name : AVT23

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            February 06, 2023

                            Lead Product(s) : Omalizumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase III

                            Recipient : Alvotech

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            06

                            Advanz Pharma

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                            Advanz Pharma

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                            Lead Product(s) : Govorestat

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Recipient : Applied Therapeutics

                            Deal Size : $138.4 million

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Applied Therapeutics Announces Partnership with Advanz Pharma for Commercialization of AT-007 (govorestat) in ...

                            Details : AT-007 (gavorestat) is a central nervous system (CNS) penetrant Aldose Reductase inhibitor (ARI) in development for the treatment of several rare neurological diseases, including Galactosemia, SORD Deficiency, and PMM2-CDG.

                            Brand Name : AT-007

                            Molecule Type : Small molecule

                            Upfront Cash : $10.6 million

                            January 04, 2023

                            Lead Product(s) : Govorestat

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Recipient : Applied Therapeutics

                            Deal Size : $138.4 million

                            Deal Type : Partnership

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                            07

                            Advanz Pharma

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                            Lead Product(s) : Aztreonam

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Recipient : Sanofi

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            ADVANZ PHARMA Further Strengthens its Specialty and Hospital Business by Acquiring an Anti-Infective Portfolio...

                            Details : ADVANZ strengthens its specialty and hospital business by gaining an anti-infective portfolio from Sanofi made up of eight anti-infectives including Azactam (aztreonam), Cefotax, Claforan, Oroken, Rulid, Suprax, Wintriaxone and Colistimethate Sodique pro...

                            Brand Name : Azactam

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 03, 2022

                            Lead Product(s) : Aztreonam

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Recipient : Sanofi

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            08

                            Advanz Pharma

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                            Advanz Pharma

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                            Lead Product(s) : Doxycycline Hyclate

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Recipient : PolyPid

                            Deal Size : $112.5 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            PolyPid Announces Exclusive Licensing Agreement with ADVANZ PHARMA for the Commercialization of D-PLEX₁₀...

                            Details : ADVANZ PHARMA receives the exclusive rights for the commercialization of PolyPid’s lead drug candidate, D-PLEX100 (doxycycline hyclate) for the prevention of surgical site infections (“SSIs”) in abdominal and cardiac surgeries, in Europe.

                            Brand Name : D-PLEX100

                            Molecule Type : Small molecule

                            Upfront Cash : $2.6 million

                            August 03, 2022

                            Lead Product(s) : Doxycycline Hyclate

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Recipient : PolyPid

                            Deal Size : $112.5 million

                            Deal Type : Licensing Agreement

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                            09

                            Advanz Pharma

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                            Advanz Pharma

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                            Lead Product(s) : Obeticholic Acid

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Approved

                            Recipient : Intercept Pharmaceuticals

                            Deal Size : $450.0 million

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            Intercept Announces Closing of Transaction with Advanz Pharma to Transfer Rights to Commercialize Ocaliva for ...

                            Details : OCALIVA (obeticholic acid), a farnesoid X receptor (FXR) agonist, is indicated for the treatment of adult patients with primary biliary cholangitis (PBC). OCALIVA is contraindicated in PBC patients with decompensated cirrhosis.

                            Brand Name : Ocaliva

                            Molecule Type : Small molecule

                            Upfront Cash : $405.0 million

                            July 01, 2022

                            Lead Product(s) : Obeticholic Acid

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Approved

                            Recipient : Intercept Pharmaceuticals

                            Deal Size : $450.0 million

                            Deal Type : Divestment

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                            10

                            Advanz Pharma

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                            Lead Product(s) : Obeticholic Acid,Ursodeoxycholic Acid

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Approved

                            Recipient : Intercept Pharmaceuticals

                            Deal Size : $450.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Intercept Announces Advanz Pharma to Acquire Ocaliva in PBC in Markets Outside the U.S. for up to $450MM, incl...

                            Details : Agreement includes rights for Advanz to commercialize orphan drug Ocaliva® (Obeticholic Acid) for PBC outside the U.S., as well as the transition to Advanz of the international commercial and medical infrastructure of Intercept.

                            Brand Name : Ocaliva

                            Molecule Type : Small molecule

                            Upfront Cash : $405.0 million

                            May 05, 2022

                            Lead Product(s) : Obeticholic Acid,Ursodeoxycholic Acid

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Approved

                            Recipient : Intercept Pharmaceuticals

                            Deal Size : $450.0 million

                            Deal Type : Acquisition

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