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            Details:

            Affini-T will leverage ElevateBio BaseCamp’s LentiPeak™ lentiviral vector technology platform and cell therapy production capabilities to advance its investigational oncogenic driver programs into clinical development.

            Lead Product(s): TCR-engineered T Cell Therapy

            Therapeutic Area: Oncology Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: ElevateBio

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Partnership November 15, 2022

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            AFNT-111, a preclinically safe and effective TCR-engineered T cell therapy targeting the oncogenic driver KRAS G12V mutation, candidates that support further clinical translation and development.

            Lead Product(s): AFNT-111

            Therapeutic Area: Oncology Product Name: AFNT-111

            Highest Development Status: IND Enabling Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable November 07, 2022

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            The partnership will leverage Metagenomi’s proprietary gene editing systems to complement Affini-T’s state-of-the-art TCR discovery and synthetic biology platforms to generate groundbreaking cell therapy products including AFNT-111.

            Lead Product(s): AFNT-111

            Therapeutic Area: Oncology Product Name: AFNT-111

            Highest Development Status: IND Enabling Product Type: Cell and Gene therapy

            Recipient: Metagenomi

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Partnership June 15, 2022

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            With proceeds from this financing, the company will operationalize its platform discovery engine and seek to drive multiple oncogene driver programs into the clinic while pursuing complementary technology licenses to bolster its cell therapy platform.

            Lead Product(s): TCR T-cell Therapy

            Therapeutic Area: Oncology Product Name: Undisclosed

            Highest Development Status: IND Enabling Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Vida Ventures

            Deal Size: $175.0 million Upfront Cash: Undisclosed

            Deal Type: Financing March 22, 2022

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