Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : TCR-engineered T Cell Therapy
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : ElevateBio
Deal Size : Undisclosed
Deal Type : Partnership
Details : Affini-T will leverage ElevateBio BaseCamp’s LentiPeak™ lentiviral vector technology platform and cell therapy production capabilities to advance its investigational oncogenic driver programs into clinical development.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
November 15, 2022
Lead Product(s) : TCR-engineered T Cell Therapy
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : ElevateBio
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : AFNT-111
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AFNT-111, a preclinically safe and effective TCR-engineered T cell therapy targeting the oncogenic driver KRAS G12V mutation, candidates that support further clinical translation and development.
Brand Name : AFNT-111
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 07, 2022
Lead Product(s) : AFNT-111
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : AFNT-111
Therapeutic Area : Oncology
Study Phase : IND Enabling
Recipient : Metagenomi
Deal Size : Undisclosed
Deal Type : Partnership
Details : The partnership will leverage Metagenomi’s proprietary gene editing systems to complement Affini-T’s state-of-the-art TCR discovery and synthetic biology platforms to generate groundbreaking cell therapy products including AFNT-111.
Brand Name : AFNT-111
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
June 15, 2022
Lead Product(s) : AFNT-111
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Recipient : Metagenomi
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : TCR T-cell Therapy
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Vida Ventures
Deal Size : $175.0 million
Deal Type : Financing
Details : With proceeds from this financing, the company will operationalize its platform discovery engine and seek to drive multiple oncogene driver programs into the clinic while pursuing complementary technology licenses to bolster its cell therapy platform.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
March 22, 2022
Lead Product(s) : TCR T-cell Therapy
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Vida Ventures
Deal Size : $175.0 million
Deal Type : Financing
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