Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : AFX3772
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : GSK
Deal Size : $3,300.0 million
Deal Type : Acquisition
GSK Completes Acquisition of Affinivax, Inc.
Details : The acquisition of Affinivax with GSK’s strategy of building a portfolio of specialty medicines and vaccines. It includes a next-generation 24-valent pneumococcal vaccine ASP3772 (AFX3772), which is based on the innovative Multiple Antigen Presenting S...
Brand Name : ASP3772
Molecule Type : Vaccine
Upfront Cash : $2,100.0 million
August 16, 2022
Lead Product(s) : AFX3772
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : GSK
Deal Size : $3,300.0 million
Deal Type : Acquisition
Lead Product(s) : AFX3772
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Affinivax’s lead MAPS pneumococcal vaccine candidate is AFX3772, which has successfully completed a Phase 2 study in older adults, with a current clinical study in toddlers and planned study in infants.
Brand Name : ASP3772
Molecule Type : Vaccine
Upfront Cash : Not Applicable
June 21, 2022
Lead Product(s) : AFX3772
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : 24-Valent Pneumococcal Vaccine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : CEPI
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AFX3772, lead vaccine candidate targeting Streptococcus pneumoniae, developed using Affinivax’s proprietary MAPS™ (Multiple Antigen-Presenting System) technology platform, is designed to elicit both B-cell and T-cell immune protection.
Brand Name : AFX3772
Molecule Type : Vaccine
Upfront Cash : Not Applicable
May 02, 2022
Lead Product(s) : 24-Valent Pneumococcal Vaccine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : CEPI
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : 24-valent Streptococcus Pneumoniae Vaccine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Recipient : Astellas Pharma
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the terms of the parties’ new agreement, the clinical development and commercialization of ASP3772, as well as royalties tied to the commercialization of Affinivax’s next generation pneumococcal vaccine products designed to treat Streptococcus ...
Brand Name : ASP3772
Molecule Type : Vaccine
Upfront Cash : $65.0 million
February 28, 2022
Lead Product(s) : 24-valent Streptococcus Pneumoniae Vaccine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Recipient : Astellas Pharma
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Covid-19 Vaccine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Discovery
Sponsor : CEPI
Deal Size : $4.5 million
Deal Type : Partnership
CEPI Partners with Affinivax to Develop a Novel COVID-19 Vaccine to Target Variants
Details : The collaborative program aims to establish preclinical proof of concept for a novel vaccine candidate designed to protect against new COVID-19 variants and that is also suitable for use in low- and middle-income countries.
Brand Name : Undisclosed
Molecule Type : Vaccine
Upfront Cash : Undisclosed
December 13, 2021
Lead Product(s) : Covid-19 Vaccine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Discovery
Sponsor : CEPI
Deal Size : $4.5 million
Deal Type : Partnership
Lead Product(s) : ASP3772
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : Astellas Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Affinivax and Astellas Present Safety and Immunogenicity Data from Phase 2 Study of ASP3772
Details : The results from the Phase 2 clinical trial demonstrated that ASP3772 was well tolerated. ASP3772 also exhibited an antibody response to each of the 24 polysaccharides, as well as an additional antibody response to the conserved pneumococcal proteins.
Brand Name : ASP3772
Molecule Type : Vaccine
Upfront Cash : Not Applicable
July 12, 2021
Lead Product(s) : ASP3772
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : Astellas Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Staphylococcus aureus vaccine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : CARB-X
Deal Size : $22.0 million
Deal Type : Funding
Details : Affinivax’s novel vaccine is being developed for the prevention of S. aureus infections, the most common form of staph infections, in high risk adult populations using the company’s Multiple Antigen Presenting System (MAPS™) vaccine technology plat...
Brand Name : Undisclosed
Molecule Type : Vaccine
Upfront Cash : Undisclosed
March 09, 2021
Lead Product(s) : Staphylococcus aureus vaccine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : CARB-X
Deal Size : $22.0 million
Deal Type : Funding
Lead Product(s) : ASP3772
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : Rock Springs Capital
Deal Size : $226.0 million
Deal Type : Series C Financing
Details : Affinivax’s novel and proprietary MAPS technology platform is designed to enable the development of a new class of vaccines that induce a broad and robust protective immune response to two key immunogenic components.
Brand Name : ASP3772
Molecule Type : Vaccine
Upfront Cash : Undisclosed
January 08, 2021
Lead Product(s) : ASP3772
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : Rock Springs Capital
Deal Size : $226.0 million
Deal Type : Series C Financing
Lead Product(s) : ASP3772
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : Astellas Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ASP3772 was observed to be safe and well tolerated in adults 18 to 64 years of age. ASP3772 exhibited robust immunogenicity to the 13 pneumococcal serotypes it shares in common with Prevnar13® as well as to an additional 11 serotypes included in ASP3772...
Brand Name : ASP3772
Molecule Type : Vaccine
Upfront Cash : Not Applicable
October 21, 2020
Lead Product(s) : ASP3772
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : Astellas Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : MAPS Pneumococcal vaccine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Viking Global Investors
Deal Size : $120.0 million
Deal Type : Series B Financing
Details : Proceeds from the Series B financing will be used to continue advancing the company’s MAPS pneumococcal vaccine program and to advance several additional vaccine candidates.
Brand Name : Undisclosed
Molecule Type : Vaccine
Upfront Cash : Undisclosed
April 23, 2020
Lead Product(s) : MAPS Pneumococcal vaccine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Viking Global Investors
Deal Size : $120.0 million
Deal Type : Series B Financing
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