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Find Clinical Drug Pipeline Developments & Deals by Affinivax

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The acquisition of Affinivax with GSK’s strategy of building a portfolio of specialty medicines and vaccines. It includes a next-generation 24-valent pneumococcal vaccine ASP3772 (AFX3772), which is based on the innovative Multiple Antigen Presenting S...

                          Brand Name : ASP3772

                          Molecule Type : Vaccine

                          Upfront Cash : $2,100.0 million

                          August 16, 2022

                          Lead Product(s) : AFX3772

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : GSK

                          Deal Size : $3,300.0 million

                          Deal Type : Acquisition

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                          02

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Affinivax’s lead MAPS pneumococcal vaccine candidate is AFX3772, which has successfully completed a Phase 2 study in older adults, with a current clinical study in toddlers and planned study in infants.

                          Brand Name : ASP3772

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          June 21, 2022

                          Lead Product(s) : AFX3772

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : AFX3772, lead vaccine candidate targeting Streptococcus pneumoniae, developed using Affinivax’s proprietary MAPS™ (Multiple Antigen-Presenting System) technology platform, is designed to elicit both B-cell and T-cell immune protection.

                          Brand Name : AFX3772

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          May 02, 2022

                          Lead Product(s) : 24-Valent Pneumococcal Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : CEPI

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Under the terms of the parties’ new agreement, the clinical development and commercialization of ASP3772, as well as royalties tied to the commercialization of Affinivax’s next generation pneumococcal vaccine products designed to treat Streptococcus ...

                          Brand Name : ASP3772

                          Molecule Type : Vaccine

                          Upfront Cash : $65.0 million

                          February 28, 2022

                          Lead Product(s) : 24-valent Streptococcus Pneumoniae Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Astellas Pharma

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          05

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The collaborative program aims to establish preclinical proof of concept for a novel vaccine candidate designed to protect against new COVID-19 variants and that is also suitable for use in low- and middle-income countries.

                          Brand Name : Undisclosed

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          December 13, 2021

                          Lead Product(s) : Covid-19 Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Discovery

                          Sponsor : CEPI

                          Deal Size : $4.5 million

                          Deal Type : Partnership

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                          06

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The results from the Phase 2 clinical trial demonstrated that ASP3772 was well tolerated. ASP3772 also exhibited an antibody response to each of the 24 polysaccharides, as well as an additional antibody response to the conserved pneumococcal proteins.

                          Brand Name : ASP3772

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          July 12, 2021

                          Lead Product(s) : ASP3772

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Astellas Pharma

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Affinivax’s novel vaccine is being developed for the prevention of S. aureus infections, the most common form of staph infections, in high risk adult populations using the company’s Multiple Antigen Presenting System (MAPS™) vaccine technology plat...

                          Brand Name : Undisclosed

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          March 09, 2021

                          Lead Product(s) : Staphylococcus aureus vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : CARB-X

                          Deal Size : $22.0 million

                          Deal Type : Funding

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                          08

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Affinivax’s novel and proprietary MAPS technology platform is designed to enable the development of a new class of vaccines that induce a broad and robust protective immune response to two key immunogenic components.

                          Brand Name : ASP3772

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          January 08, 2021

                          Lead Product(s) : ASP3772

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Rock Springs Capital

                          Deal Size : $226.0 million

                          Deal Type : Series C Financing

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                          09

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : ASP3772 was observed to be safe and well tolerated in adults 18 to 64 years of age. ASP3772 exhibited robust immunogenicity to the 13 pneumococcal serotypes it shares in common with Prevnar13® as well as to an additional 11 serotypes included in ASP3772...

                          Brand Name : ASP3772

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          October 21, 2020

                          Lead Product(s) : ASP3772

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Astellas Pharma

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Proceeds from the Series B financing will be used to continue advancing the company’s MAPS pneumococcal vaccine program and to advance several additional vaccine candidates.

                          Brand Name : Undisclosed

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          April 23, 2020

                          Lead Product(s) : MAPS Pneumococcal vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Viking Global Investors

                          Deal Size : $120.0 million

                          Deal Type : Series B Financing

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