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Find Clinical Drug Pipeline Developments & Deals by AffyImmune Therapeutics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : AIC100, an ICAM-1 targeting and affinity-tuned LFA-1 binder CAR T-cell therapy. Currently, it is being evaluated for the treatment of patients with recurrent anaplastic thyroid cancer.

                          Brand Name : AIC100

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          July 23, 2024

                          Lead Product(s) : AIC100

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : The funding will be used to advance the Phase 1 study of AffyImmune’s lead asset, AIC100, for the treatment of anaplastic thyroid cancer and refractory poorly differentiated thyroid cancer.

                          Brand Name : AIC100

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          October 07, 2021

                          Lead Product(s) : AIC100

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : ORI Capital

                          Deal Size : $30.0 million

                          Deal Type : Series A Financing

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                          03

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : The FDA's Fast Track designation is designed for AIC100 facilitate development and expedite review of drug candidates to treat serious conditions and address an unmet medical need.

                          Brand Name : AIC100

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          May 17, 2021

                          Lead Product(s) : AIC100

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Weill Cornell Medicine

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          CPhI India 2024
                          Not Confirmed
                          CPhI India 2024
                          Not Confirmed

                          Details : The study is being conducted at Weill Cornell Medicine. Unlike most CAR-T cell products, AIC100 was designed to specifically target tumor cells overexpressing the target (ICAM-1) while avoiding normal cells expressing lower levels.

                          Brand Name : AIC100

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          October 29, 2020

                          Lead Product(s) : AIC100

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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