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Find Clinical Drug Pipeline Developments & Deals by AFYX Therapeutics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Rivelin-CLO is the first biodegradable oral adhesive patch designed for local delivery of clobetasol to treat symptomatic Oral Lichen Planus (OLP) lesions. First study to show the successful transmucosal delivery of a corticosteroid using electrospun pat...

                          Product Name : Rivelin-CLO

                          Product Type : Steroid

                          Upfront Cash : Inapplicable

                          November 03, 2021

                          Lead Product(s) : Clobetasol Propionate

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : The study showed that a) Rivelin patch was formulated with therapeutic anti-TNFα antibody fragments, b) those fragments were successfully delivered directly to inflamed mucosal tissue, and c) that the antibodies maintained a neutralizing effect on infla...

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          July 09, 2021

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Dental and Oral Health

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : In this Phase 2 study investigating Rivelin-CLO across more than 20 clinical trial sites, a 20-µg dose resulted in a clinically significant reduction in OLP ulcer size, improvements in symptoms and quality of life, and a favorable safety profile compare...

                          Product Name : Rivelin-CLO

                          Product Type : Steroid

                          Upfront Cash : Inapplicable

                          April 15, 2021

                          Lead Product(s) : Clobetasol Propionate

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Study conducted in OLP patients with the 20?g dose of Rivelin-CLO demonstrated a statistically significant improvement in ulcer area, and continued to show improvement through the end of 4 weeks.

                          Product Name : Rivelin-CLO

                          Product Type : Steroid

                          Upfront Cash : Inapplicable

                          April 22, 2020

                          Lead Product(s) : Clobetasol Propionate

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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