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    [{"orgOrder":0,"company":"AgomAb Therapeutics N.V","sponsor":"Redmile Group","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"","productType":"Large molecule","year":"2021","type":"Series B Financing","leadProduct":"AGMB-101","moa":"MET","graph1":"Immunology","graph2":"IND Enabling","graph3":"AgomAb Therapeutics N.V","amount2":0.070000000000000007,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0.070000000000000007,"dosageForm":"","sponsorNew":"AgomAb Therapeutics N.V \/ Redmile Group","highestDevelopmentStatusID":"5","companyTruncated":"AgomAb Therapeutics N.V \/ Redmile Group"},{"orgOrder":0,"company":"AgomAb Therapeutics N.V","sponsor":"Origo Biopharma","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"","productType":"Small molecule","year":"2021","type":"Acquisition","leadProduct":"ORG-129","moa":"TGF-beta","graph1":"Gastroenterology","graph2":"Phase I","graph3":"AgomAb Therapeutics 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    Find Clinical Drug Pipeline Developments & Deals by AgomAb Therapeutics N.V

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                            01

                            AgomAb Therapeutics N.V

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                            AgomAb Therapeutics N.V

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                            Lead Product(s) : AGMB-129

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Sanofi

                            Deal Size : $89.0 million

                            Deal Type : Series D Financing

                            DEALS_DEV arrow-down

                            Agomab Announces $89 Million Series D Financing to Support Broad Fibrosis-Focused Pipeline

                            Details : The proceeds from the financing will be used to further advance the ongoing clinical development of Agomab’s lead candidate, AGMB-129 in patients with fibrostenosing Crohn’s disease (FSCD).

                            Brand Name : AGMB-129

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 25, 2024

                            Lead Product(s) : AGMB-129

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Sanofi

                            Deal Size : $89.0 million

                            Deal Type : Series D Financing

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                            02

                            AgomAb Therapeutics N.V

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                            AgomAb Therapeutics N.V

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                            Lead Product(s) : AGMB-447

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Agomab Receives FDA Orphan Drug Designation for AGMB-447 in Idiopathic Pulmonary Fibrosis

                            Details : AGMB-447 is an inhaled lung-restricted small molecule inhibitor of ALK5 (TGFβRI or ALK5). It is under clinical development for the treatment of patients with idiopathic pulmonary fibrosis (IPF).

                            Brand Name : AGMB-447

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 06, 2024

                            Lead Product(s) : AGMB-447

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            AgomAb Therapeutics N.V

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                            Lead Product(s) : AGMB-447

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Agomab Starts Phase 1 Clinical Study for AGMB-447 in Healthy Subjects and Patients with Idiopathic Pulmonary F...

                            Details : AGMB-447 is an inhaled lung-restricted small molecule inhibitor of ALK5 (TGFβRI or ALK5). It is under phase 1 clinical development for the treatment of patients with idiopathic pulmonary fibrosis (IPF).

                            Brand Name : AGMB-447

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 14, 2023

                            Lead Product(s) : AGMB-447

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            AgomAb Therapeutics N.V

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                            AgomAb Therapeutics N.V

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                            Lead Product(s) : ORG-129

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase I

                            Sponsor : EQT Life Sciences

                            Deal Size : $100.0 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            Agomab Raises $100 Million Series C to Advance Fibrosis-focused Pipeline

                            Details : Proceeds will support Phase 2 candidate AGMB-129/ORG-129 for Fibrostenosing Crohn’s Disease and development of a highly innovative pipeline of anti-fibrotic and regenerative therapies, including AGMB-447 for idiopathic pulmonary fibrosis.

                            Brand Name : AGMB-129

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 11, 2023

                            Lead Product(s) : ORG-129

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase I

                            Sponsor : EQT Life Sciences

                            Deal Size : $100.0 million

                            Deal Type : Series C Financing

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                            05

                            AgomAb Therapeutics N.V

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                            AgomAb Therapeutics N.V

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                            Lead Product(s) : AGMB-129

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Agomab Receives FDA Fast Track Designation for AGMB-129 in Fibrostenosing Crohn’s Disease and Starts STENOVA...

                            Details : AGMB-129 (ORG-129) is an oral, small molecule GI-restricted inhibitor of ALK-5 (or TGFbR1) for the treatment of Fibrostenosing Crohn’s Disease. TGFb is a known master regulator of fibrosis and preliminary clinical data supports targeting the pathway in...

                            Brand Name : AGMB-129

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 05, 2023

                            Lead Product(s) : AGMB-129

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            AgomAb Therapeutics N.V

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                            Lead Product(s) : ORG-129

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Agomab Reports Positive Phase 1 Results with AGMB-129, a GI-restricted ALK5 Inhibitor for Fibrostenosing Crohn...

                            Details : AGMB-129 (ORG-129) is an oral, small molecule GI-restricted inhibitor of ALK-5 (or TGFbR1) for the treatment of Fibrostenosing Crohn’s Disease. TGFb is a known master regulator of fibrosis and preliminary clinical data supports targeting the pathway in...

                            Brand Name : AGMB-129

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            February 02, 2023

                            Lead Product(s) : ORG-129

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            AgomAb Therapeutics N.V

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                            AgomAb Therapeutics N.V

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                            Lead Product(s) : ORG-129

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase I

                            Sponsor : Pfizer Inc

                            Deal Size : $114.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Agomab Raises Additional $40.5 Million Through Series B Extension Bringing Total Amount to $114 Million

                            Details : Agomab’s pipeline consists of its lead candidate AGMB-129, a gastrointestinal tract restricted ALK-5 inhibitor for the treatment of fibrostenotic Crohn’s disease that is currently being investigated in a Phase 1 clinical trial in healthy volunteers.

                            Brand Name : AGMB-129

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            July 13, 2022

                            Lead Product(s) : ORG-129

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase I

                            Sponsor : Pfizer Inc

                            Deal Size : $114.0 million

                            Deal Type : Series B Financing

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                            08

                            AgomAb Therapeutics N.V

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                            Lead Product(s) : ORG-129

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase I

                            Recipient : Origo Biopharma

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Agomab Therapeutics to Acquire Origo Biopharma

                            Details : The combined organization will focus on translating growth factor signaling pathways into innovative therapies including lead program, ORG-129, a gastrointestinal tract restricted ALK-5 inhibitor currently in a Phase 1 clinical trial.

                            Brand Name : ORG-129

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 28, 2021

                            Lead Product(s) : ORG-129

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase I

                            Recipient : Origo Biopharma

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            09

                            AgomAb Therapeutics N.V

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                            AgomAb Therapeutics N.V

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                            Lead Product(s) : AGMB-101

                            Therapeutic Area : Immunology

                            Study Phase : IND Enabling

                            Sponsor : Redmile Group

                            Deal Size : $74.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            AgomAb Therapeutics Raises $74 Million Series B to Advance Regenerative Pathway Modulators

                            Details : Proceeds to further advance lead compound AGMB-101 and expand pipeline in inflammatory, metabolic and fibrotic diseases.

                            Brand Name : AGMB-101

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            March 10, 2021

                            Lead Product(s) : AGMB-101

                            Therapeutic Area : Immunology

                            Highest Development Status : IND Enabling

                            Sponsor : Redmile Group

                            Deal Size : $74.0 million

                            Deal Type : Series B Financing

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