Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Allergy Partners
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Palforzia (arachis hypogaea) is an oral immunotherapy (OIT) for the mitigation of allergic reactions, including anaphylaxis, that may occur with accidental exposure to peanut in patients aged 4 through 17 years with a confirmed diagnosis of peanut allerg...
Product Name : Palforzia
Product Type : Plant Extract/Herbal
Upfront Cash : Undisclosed
October 13, 2022
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Allergy Partners
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Aimmune Tx to Present New Data for PALFORZIA at the EAACI
Details : Self-and caregiver proxy-reported total scores on the FAQLQ for PALFORZIA (arachis hypogaea allergen powder-dnfp)-treated participants generally improved at trial exit from baseline; change in total scores on the FAIM improved throughout all trials.
Product Name : Palforzia
Product Type : Plant Extract/Herbal
Upfront Cash : Inapplicable
June 30, 2022
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Data presented at the meeting suggest that continued long-term treatment with PALFORZIA induced long-term immunomodulation, indicating a continued shift away from pretreatment sensitivity to peanut.
Product Name : Palforzia
Product Type : Plant Extract/Herbal
Upfront Cash : Inapplicable
December 11, 2021
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Aimmune to Present New Two-Year Treatment Satisfaction Data
Details : Patient-reported treatment satisfaction was evaluated over two years following daily treatment with PALFORZIA in a clinical trial setting using the Treatment Satisfaction Questionnaire for Medication (TSQM-9).
Product Name : Palforzia
Product Type : Plant Extract/Herbal
Upfront Cash : Inapplicable
September 07, 2021
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : PALFORZIA can be readily implemented in clinical settings for the treatment of PA. Results show that PALFORZIA treatment was successfully incorporated in practice by health care providers without prior OIT experience.
Product Name : Palforzia
Product Type : Plant Extract/Herbal
Upfront Cash : Inapplicable
May 11, 2021
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The analysis showed that peanut-allergic patients ages 4 through 17 who continued daily maintenance with PALFORZIA for up to two years were able to tolerate higher doses of peanut during the food exit challenge.
Product Name : Palforzia
Product Type : Plant Extract/Herbal
Upfront Cash : Inapplicable
April 08, 2021
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : In patients with peanut allergy who continued daily treatment with PALFORZIA for up to 3.5 years reported adverse events were mostly mild, occurred early on in treatment, and declined over the course of treatment.
Product Name : Palforzia
Product Type : Plant Extract/Herbal
Upfront Cash : Inapplicable
February 25, 2021
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The approval was based on a package of data, including from two phase 3 clinical trials PALISADE and ARTEMIS. In both studies, PALFORZIA treatment resulted in a significant increase in the amount of peanut protein tolerated, compared to placebo.
Product Name : Palforzia
Product Type : Plant Extract/Herbal
Upfront Cash : Inapplicable
December 21, 2020
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ARTEMIS met all primary, secondary and safety endpoints, and demonstrated that patients treated with PALFORZIA experienced a high degree of desensitization to peanut with an anticipated and manageable safety profile.
Product Name : Palforzia
Product Type : Plant Extract/Herbal
Upfront Cash : Inapplicable
October 16, 2020
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Nestle Health Sciences SA
Deal Size : $1,930.0 million
Deal Type : Acquisition
Nestlé to Acquire Aimmune Therapeutics
Details : Aimmune's recently approved therapy Palforzia® would expand Nestlé Health Science portfolio with first and only FDA-approved treatment to help reduce the frequency and severity of allergic reactions to peanuts in children.
Product Name : Palforzia
Product Type : Plant Extract/Herbal
Upfront Cash : $1,930.0 million
August 31, 2020
Lead Product(s) : Arachis Hypogaea Allergen
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Nestle Health Sciences SA
Deal Size : $1,930.0 million
Deal Type : Acquisition