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Find Clinical Drug Pipeline Developments & Deals by Aimmune Therapeutics

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : Palforzia (arachis hypogaea) is an oral immunotherapy (OIT) for the mitigation of allergic reactions, including anaphylaxis, that may occur with accidental exposure to peanut in patients aged 4 through 17 years with a confirmed diagnosis of peanut allerg...

                          Product Name : Palforzia

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Undisclosed

                          October 13, 2022

                          Lead Product(s) : Arachis Hypogaea Allergen

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved FDF

                          Sponsor : Allergy Partners

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          02

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : Self-and caregiver proxy-reported total scores on the FAQLQ for PALFORZIA (arachis hypogaea allergen powder-dnfp)-treated participants generally improved at trial exit from baseline; change in total scores on the FAIM improved throughout all trials.

                          Product Name : Palforzia

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          June 30, 2022

                          Lead Product(s) : Arachis Hypogaea Allergen

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : Data presented at the meeting suggest that continued long-term treatment with PALFORZIA induced long-term immunomodulation, indicating a continued shift away from pretreatment sensitivity to peanut.

                          Product Name : Palforzia

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          December 11, 2021

                          Lead Product(s) : Arachis Hypogaea Allergen

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : Patient-reported treatment satisfaction was evaluated over two years following daily treatment with PALFORZIA in a clinical trial setting using the Treatment Satisfaction Questionnaire for Medication (TSQM-9).

                          Product Name : Palforzia

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          September 07, 2021

                          Lead Product(s) : Arachis Hypogaea Allergen

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : PALFORZIA can be readily implemented in clinical settings for the treatment of PA. Results show that PALFORZIA treatment was successfully incorporated in practice by health care providers without prior OIT experience.

                          Product Name : Palforzia

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          May 11, 2021

                          Lead Product(s) : Arachis Hypogaea Allergen

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : The analysis showed that peanut-allergic patients ages 4 through 17 who continued daily maintenance with PALFORZIA for up to two years were able to tolerate higher doses of peanut during the food exit challenge.

                          Product Name : Palforzia

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          April 08, 2021

                          Lead Product(s) : Arachis Hypogaea Allergen

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : In patients with peanut allergy who continued daily treatment with PALFORZIA for up to 3.5 years reported adverse events were mostly mild, occurred early on in treatment, and declined over the course of treatment.

                          Product Name : Palforzia

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          February 25, 2021

                          Lead Product(s) : Arachis Hypogaea Allergen

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : The approval was based on a package of data, including from two phase 3 clinical trials PALISADE and ARTEMIS. In both studies, PALFORZIA treatment resulted in a significant increase in the amount of peanut protein tolerated, compared to placebo.

                          Product Name : Palforzia

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          December 21, 2020

                          Lead Product(s) : Arachis Hypogaea Allergen

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : ARTEMIS met all primary, secondary and safety endpoints, and demonstrated that patients treated with PALFORZIA experienced a high degree of desensitization to peanut with an anticipated and manageable safety profile.

                          Product Name : Palforzia

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          October 16, 2020

                          Lead Product(s) : Arachis Hypogaea Allergen

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          10

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : Aimmune's recently approved therapy Palforzia® would expand Nestlé Health Science portfolio with first and only FDA-approved treatment to help reduce the frequency and severity of allergic reactions to peanuts in children.

                          Product Name : Palforzia

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : $1,930.0 million

                          August 31, 2020

                          Lead Product(s) : Arachis Hypogaea Allergen

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved FDF

                          Sponsor : Nestle Health Sciences SA

                          Deal Size : $1,930.0 million

                          Deal Type : Acquisition

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