Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Arachis Hypogaea
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Allergy Partners
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Palforzia (arachis hypogaea) is an oral immunotherapy (OIT) for the mitigation of allergic reactions, including anaphylaxis, that may occur with accidental exposure to peanut in patients aged 4 through 17 years with a confirmed diagnosis of peanut allerg...
Brand Name : Palforzia
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 13, 2022
Lead Product(s) : Arachis Hypogaea
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Allergy Partners
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Arachis Hypogaea
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Aimmune Tx to Present New Data for PALFORZIA at the EAACI
Details : Self-and caregiver proxy-reported total scores on the FAQLQ for PALFORZIA (arachis hypogaea allergen powder-dnfp)-treated participants generally improved at trial exit from baseline; change in total scores on the FAIM improved throughout all trials.
Brand Name : Palforzia
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 30, 2022
Lead Product(s) : Arachis Hypogaea
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Arachis Hypogaea Allergen Powder-dnfp
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Data presented at the meeting suggest that continued long-term treatment with PALFORZIA induced long-term immunomodulation, indicating a continued shift away from pretreatment sensitivity to peanut.
Brand Name : Palforzia
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 12, 2021
Lead Product(s) : Arachis Hypogaea Allergen Powder-dnfp
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Arachis Hypogaea Allergen Powder-dnfp
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PALFORZIA can be readily implemented in clinical settings for the treatment of PA. Results show that PALFORZIA treatment was successfully incorporated in practice by health care providers without prior OIT experience.
Brand Name : Palforzia
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 05, 2021
Lead Product(s) : Arachis Hypogaea Allergen Powder-dnfp
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Arachis Hypogaea Allergen Powder-dnfp
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The analysis showed that peanut-allergic patients ages 4 through 17 who continued daily maintenance with PALFORZIA for up to two years were able to tolerate higher doses of peanut during the food exit challenge.
Brand Name : Palforzia
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 04, 2021
Lead Product(s) : Arachis Hypogaea Allergen Powder-dnfp
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Arachis Hypogaea Allergen Powder-dnfp
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Aimmune to Present New Two-Year Treatment Satisfaction Data
Details : Patient-reported treatment satisfaction was evaluated over two years following daily treatment with PALFORZIA in a clinical trial setting using the Treatment Satisfaction Questionnaire for Medication (TSQM-9).
Brand Name : Palforzia
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 09, 2021
Lead Product(s) : Arachis Hypogaea Allergen Powder-dnfp
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Arachis hypogaea allergen powder-dnfp
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : In patients with peanut allergy who continued daily treatment with PALFORZIA for up to 3.5 years reported adverse events were mostly mild, occurred early on in treatment, and declined over the course of treatment.
Brand Name : Palforzia
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 25, 2021
Lead Product(s) : Arachis hypogaea allergen powder-dnfp
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Peanut Allergen Powder-dnfp
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The approval was based on a package of data, including from two phase 3 clinical trials PALISADE and ARTEMIS. In both studies, PALFORZIA treatment resulted in a significant increase in the amount of peanut protein tolerated, compared to placebo.
Brand Name : Palforzia
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 21, 2020
Lead Product(s) : Peanut Allergen Powder-dnfp
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Peanut Allergen Powder-dnfp
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ARTEMIS met all primary, secondary and safety endpoints, and demonstrated that patients treated with PALFORZIA experienced a high degree of desensitization to peanut with an anticipated and manageable safety profile.
Brand Name : Palforzia
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 16, 2020
Lead Product(s) : Peanut Allergen Powder-dnfp
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Peanut Allergen Powder-dnfp
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Nestle Health Sciences SA
Deal Size : $1,930.0 million
Deal Type : Acquisition
Nestlé to Acquire Aimmune Therapeutics
Details : Aimmune's recently approved therapy Palforzia® would expand Nestlé Health Science portfolio with first and only FDA-approved treatment to help reduce the frequency and severity of allergic reactions to peanuts in children.
Brand Name : Palforzia
Molecule Type : Large molecule
Upfront Cash : $1,930.0 million
August 31, 2020
Lead Product(s) : Peanut Allergen Powder-dnfp
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Nestle Health Sciences SA
Deal Size : $1,930.0 million
Deal Type : Acquisition
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