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    [{"orgOrder":0,"company":"Akston Biosciences","sponsor":"University Medical Center Groningen","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2021","type":"Not Applicable","leadProduct":"AKS-452","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase II\/ Phase III","graph3":"Akston Biosciences","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Akston Biosciences \/ University Medical Center Groningen","highestDevelopmentStatusID":"9","companyTruncated":"Akston Biosciences \/ University Medical Center Groningen"},{"orgOrder":0,"company":"Akston Biosciences","sponsor":"Seppic","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"FRANCE","productType":"Vaccine","year":"2021","type":"Agreement","leadProduct":"Engineered 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    Find Clinical Drug Pipeline Developments & Deals by Akston Biosciences

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                            01

                            Akston Biosciences

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                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Stelis Biopharma

                            Deal Size : Undisclosed

                            Deal Type : Termination

                            DEALS_DEV arrow-down

                            Akston Biosciences Ends Vaccine Partnership with Stelis, Continues to Advance COVID Universal Booster EUA

                            Details : Akston has reclaimed all rights to AKS-452, a room temperature stable, low-cost, protein subunit COVID-19 vaccine. Akston is continuing its progress to secure Emergency Use Authorization (EUA) in India and has begun working with a new CDMO to produce AKS...

                            Brand Name : AKS-452

                            Molecule Type : Vaccine

                            Upfront Cash : Undisclosed

                            March 07, 2023

                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Stelis Biopharma

                            Deal Size : Undisclosed

                            Deal Type : Termination

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                            02

                            Akston Biosciences

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                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Akston Biosciences Announces Positive Interim Phase II Results from COVID “Universal” Booster Vaccine Tria...

                            Details : AKS-452 is a second-generation vaccine based on Akston’s novel Fc-fusion platform. Its composition provides direct presentation to the immune system and robust protection against virus variants.

                            Brand Name : AKS-452

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            November 01, 2022

                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II/ Phase III

                            Sponsor : Biolexis

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Biolexis and Akston Biosciences Announce Encouraging Top-Line Results from Phase II/III Trial of their Thermos...

                            Details : Results of 100 subjects bridging study and 1,500 subjects placebo-controlled trial of Akston’s AKS-452 announced. Interim analysis shows a 91% seroconversion rate.

                            Brand Name : AKS-452

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            June 24, 2022

                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Biolexis

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Akston Biosciences

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                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Akston Biosciences Doses First Participants in Phase II Clinical Trial for Shelf-Stable COVID-19 Booster

                            Details : Up to 600 volunteers will participate in an AKS-452 COVID booster study in the Netherlands to investigate boosting the immune response of those previously vaccinated with EMA-registered vaccines.

                            Brand Name : AKS-452

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            May 12, 2022

                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Akston Biosciences

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                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II/ Phase III

                            Sponsor : University Medical Centre Groningen

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Akston Biosciences Doses First Volunteers in Phase II/III Clinical Trial of Low Cost, Shelf Stable COVID-19 Va...

                            Details : AKS-452 or AmbiVax-CTM is a first-of-its-kind thermostable COVID-19 vaccine developed for all parts of the world. AmbiVax-CTM is a SARS-CoV-2 protein subunit vaccine designed to induce a Th1/Th2 mixed immune response in patients against the Receptor Bind...

                            Brand Name : AmbiVax-C

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            April 07, 2022

                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : University Medical Centre Groningen

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Akston Biosciences Receives Regulatory Approval for Phase II Clinical Trial for Shelf-Stable COVID-19 Vaccine ...

                            Details : AKS-452 is a protein sub-unit vaccine, a type of vaccine used safely and widely for decades. AKS-452 does not contain mRNA technology, viral vectors, or a weakened SARS-CoV-2 virus.

                            Brand Name : AKS-452

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            March 31, 2022

                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Akston Biosciences

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                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Recipient : Biolexis

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Akston Biosciences and Biolexis Collaborate to Launch a Room Temperature Stable 2nd Generation COVID-19 Vaccin...

                            Details : Under the agreement, Biolexis gains the right to manufacture and commercialize AKS-452 (branded as AmbiVax-CTM) in India and over 130 countries in Asia, Latin America, and Africa largely covering the low-and-middle-income countries (LMICs).

                            Brand Name : AmbiVax-C

                            Molecule Type : Vaccine

                            Upfront Cash : Undisclosed

                            March 17, 2022

                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Recipient : Biolexis

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            08

                            Akston Biosciences

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                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Akston Biosciences Doses First Subjects in Phase II Clinical Trial in India of Second-Generation COVID-19 Vacc...

                            Details : AKS-452 is a SARS-CoV-2 vaccine candidate designed to induce a Th1/Th2 mixed immune response in patients against the Receptor Binding Domain of the novel coronavirus spike protein.

                            Brand Name : AKS-452

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            November 20, 2021

                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Akston Biosciences

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                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Akston Biosciences Doses First Subjects in Phase II Clinical Trial of Second-Generation Protein Subunit COVID-...

                            Details : The Phase I trial showed AKS-452 to be safe and well-tolerated. Most importantly, AKS-452 produced a 100% seroconversion rate in the 90 microgram single-dose regimen, as well as in the 45 microgram two-dose regimen.

                            Brand Name : AKS-452

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            August 05, 2021

                            Lead Product(s) : AKS-452

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Akston Biosciences

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                            Lead Product(s) : Engineered SARS-CoV-2-RBD-Fc Fusion Protein Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I/ Phase II

                            Recipient : Seppic

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Akston Biosciences Announces Commercial Supply Agreement of Seppic’s Adjuvant to Formulate Akston COVID-19 V...

                            Details : AKS-452 is a protein subunit vaccine that is in Phase II testing at the University Medical Center Groningen (UMCG), one of the largest hospitals in the Netherlands.

                            Brand Name : AKS-452

                            Molecule Type : Vaccine

                            Upfront Cash : Undisclosed

                            July 21, 2021

                            Lead Product(s) : Engineered SARS-CoV-2-RBD-Fc Fusion Protein Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Seppic

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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