Lead Product(s) : Aldoxorubicin
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : ImmunityBio
Deal Size : $356.0 million
Deal Type : Termination
LadRx and ImmunityBio Mutually Agree to Terminate Aldoxorubicin License
Details : With the termination, LadRx regains control of INNO-206 (aldoxorubicin), a rationally-engineered cytotoxic which delivers well-established anti-cancer agent, doxorubicin, into the tumor.
Brand Name : INNO-206
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 03, 2024
Lead Product(s) : Aldoxorubicin
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : ImmunityBio
Deal Size : $356.0 million
Deal Type : Termination
Lead Product(s) : Aldoxorubicin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
LadRx Highlights Patent Issued for Its LADR Technology
Details : INNO-206 (aldoxorubicin) is a prodrug of doxorubicin that binds endogenous albumin after administration. The bound doxorubicin is released in the acidic environment of the tumor cell through cleavage of an acid sensitive linker and expresses antitumor ef...
Brand Name : INNO-206
Molecule Type :
Upfront Cash : Not Applicable
March 27, 2023
Lead Product(s) : Aldoxorubicin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aldoxorubicin
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
CytRx Partners with Oncology Development Expert to Advance LADR Platform
Details : Aldoxorubicin, a rationally-engineered cytotoxic delivers well-established anti-cancer agent, doxorubicin, into tumor, utilizes an acid-sensitive linker that selectively binds to albumin, which may allow cytotoxic payload to preferentially accumulate in ...
Brand Name : INNO-206
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 20, 2022
Lead Product(s) : Aldoxorubicin
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aldoxorubicin
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : CytRx Corporation
Deal Size : Undisclosed
Deal Type : Merger
Details : Through the merger with Centurion, the next-generation LADR drugs including INNO-206, are now within CytRx and poised for the last steps required for first-in-human studies, an achievement that could be expected to generate significant value for sharehol...
Brand Name : INNO-206
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 09, 2022
Lead Product(s) : Aldoxorubicin
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : CytRx Corporation
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Aldoxorubicin,Paclitaxel,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
CytRx Corporation Highlights Latest Positive Event From its Licensed Drug Aldoxorubicin
Details : CytRx partner immunitybio announces the initiation of a Phase 2 registrational-intent study of its immunotherapy including aldoxorubicin in metastatic pancreatic cancer.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 21, 2020
Lead Product(s) : Aldoxorubicin,Paclitaxel,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aldoxorubicin
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : ImmunityBio
Deal Size : $343.0 million
Deal Type : Agreement
CytRx Corporation Highlights Significant Positive Events From its Licensed Drug Aldoxorubicin
Details : CytRx out-licensed global development, manufacturing, and commercialization rights for aldoxorubicin to ImmunityBio Inc. in July 2017.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 29, 2020
Lead Product(s) : Aldoxorubicin
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : ImmunityBio
Deal Size : $343.0 million
Deal Type : Agreement
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