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    [{"orgOrder":0,"company":"Chugai Pharmaceutical","sponsor":"Genentech","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Alectinib Hydrochloride","moa":"","graph1":"Oncology","graph2":"Approved","graph3":"Chugai Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Chugai Pharmaceutical \/ Genentech","highestDevelopmentStatusID":"12","companyTruncated":"Chugai Pharmaceutical \/ Genentech"},{"orgOrder":0,"company":"F. Hoffmann-La Roche","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Alectinib Hydrochloride","moa":"","graph1":"Oncology","graph2":"Approved","graph3":"F. 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                            01

                            F. Hoffmann-La Roche

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                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Roche’s Alecensa Receives NICE Recommendation to Treat ALK-Positive Lung Cancer

                            Details : Alecensa (alectinib) is an ALK tyrosine kinase receptor inhibitor, approved by NICE authority for treating patients with ALK-positive early-stage NSCLC.

                            Brand Name : Alecensa

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 21, 2024

                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Chugai Pharmaceutical

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                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Chugai's Alecensa Approved in Japan for Adjuvant Treatment in Early-Stage ALK+ NSCLC

                            Details : Alecensa (alectinib) is an ALK tyrosine kinase receptor inhibitor, approved y MHLW authority for treating patients with ALK-positive early-stage NSCLC.

                            Brand Name : Alecensa

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 29, 2024

                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Chugai Pharmaceutical

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                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Taiwan FDA approves Chugai’s Alecensa for the treatment of early stage ALK-positive NSCLC

                            Details : Alecensa (alectinib) is a tyrosine kinase inhibitor that targets ALK and RET. It is used as adjuvant treatment after surgery in patients with early-stage ALK-positive non–small cell lung cancer.

                            Brand Name : Alecensa

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 03, 2024

                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            F. Hoffmann-La Roche

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                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            EC Approves Roche’s Alecensa as First Adjuvant Treatment for ALK-Positive Lung Cancer

                            Details : Alecensa (alectinib) is an ALK tyrosine kinase receptor inhibitor, which is now approved in EU for postoperative adjuvant therapy for ALK fusion gene-positive non-small cell lung cancer.

                            Brand Name : Alecensa

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 10, 2024

                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

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                            05

                            F. Hoffmann-La Roche

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                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            CHMP Recommends EU Approval Of Alecensa As Adjuvant Treatment For ALK-Positive Lung Cancer

                            Details : Alecensa (alectinib) is an ALK tyrosine kinase receptor inhibitor, which is under phase 3 clinical trials for postoperative adjuvant therapy for ALK fusion gene-positive non-small cell lung cancer.

                            Brand Name : Alecensa

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 30, 2024

                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Genentech

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                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            FDA Approves Genentech's Alecensa as First Adjuvant Treatment for ALK-Positive Lung Cancer

                            Details : Alecensa (alectinib) is an ALK tyrosine kinase receptor inhibitor, which is now approved & indicated for postoperative adjuvant therapy for ALK fusion gene-positive non-small cell lung cancer.

                            Brand Name : Alecensa

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 18, 2024

                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            F. Hoffmann-La Roche

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                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Alectinib Deemed “Highly Promising” for Pediatric ALK Fusion-Positive Cancers

                            Details : Alecensa (alectinib) is an ALK tyrosine kinase receptor inhibitor, which is currentlt being evaluated in pediatric patients with ALK fusion-positive cancers.

                            Brand Name : Alecensa

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 11, 2024

                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Nuvectis Pharma

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                            Lead Product(s) : NXP900,Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Nuvectis' NXP900 Shows Strong Activity in Non-Small Lung Cancer Cells

                            Details : NXP900 is an oral small molecule inhibitor of the SRC Family of Kinases is being evaluated in early-stage clinical trial in combination with Alectinib for the treatment of non-small cell lung cancer.

                            Brand Name : NXP900

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 08, 2024

                            Lead Product(s) : NXP900,Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            F. Hoffmann-La Roche

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                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            FDA Grants Priority Review to Adjuvant Alectinib for Early-Stage ALK+ NSCLC

                            Details : Alecensa (alectinib) is a tyrosine kinase inhibitor that targets ALK and RET. It is use as adjuvant treatment after surgery in patients with early-stage ALK-positive non–small cell lung cancer.

                            Brand Name : Alecensa

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 31, 2024

                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Chugai Pharmaceutical

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                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Chugai Files for Additional Indication of Alecensa for Postoperative Adjuvant Therapy for ALK Fusion Gene-Posi...

                            Details : Alecensa (alectinib) is an ALK tyrosine kinase receptor inhibitor, which is under phase 3 clinical trials for postoperative adjuvant therapy for ALK fusion gene-positive non-small cell lung cancer.

                            Brand Name : Alecensa

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 15, 2023

                            Lead Product(s) : Alectinib Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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