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                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : ALG-000184 is a potent potential best/first-in-class oral small molecule capsid assembly modulator (CAM-E) being developed for chronic hepatitis B.

                          Brand Name : ALG-000184

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 22, 2024

                          Lead Product(s) : ALG-000184,Carbamazepine,Itraconazole

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : ALG-055009 appears to be a best-in-class thyroid hormone receptor beta (THR-ß) agonist, which is being evaluated for the treatment of metabolic dysfunction-associated steatohepatitis.

                          Brand Name : ALG-055009

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 19, 2024

                          Lead Product(s) : ALG-055009

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : ALG-055009 appears to be a best-in-class thyroid hormone receptor beta (THR-ß) agonist, which is being evaluated for the treatment of metabolic dysfunction-associated steatohepatitis.

                          Brand Name : ALG-055009

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 19, 2024

                          Lead Product(s) : ALG-055009

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : ALG-055009 appears to be a best-in-class thyroid hormone receptor beta (THR-ß) agonist, which is being evaluated for the treatment of metabolic dysfunction-associated steatohepatitis.

                          Brand Name : ALG-055009

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 18, 2024

                          Lead Product(s) : ALG-055009

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Amoytop will sponsor a Phase 1b exploratory study evaluating the efficacy and safety of ALG-000184 in combination with PEGBING (Mipeginterferon alfa-2b) in chronic hepatitis B patients in China.

                          Brand Name : ALG-000184

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          July 22, 2024

                          Lead Product(s) : ALG-000184,Mipeginterferon Alfa-2b

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : Xiamen Amoytop Biotech

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          06

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : ALG-055009 appears to be a best-in-class thyroid hormone receptor beta (THR-ß) agonist discovered by Aligos for the treatment of metabolic dysfunction-associated steatohepatitis (MASH).

                          Brand Name : ALG-055009

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          May 21, 2024

                          Lead Product(s) : ALG-055009

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : ALG-055009 appears to be a best-in-class thyroid hormone receptor beta (THR-ß) agonist, which is being evaluated for the treatment of metabolic dysfunction-associated steatohepatitis.

                          Brand Name : ALG-055009

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 03, 2024

                          Lead Product(s) : ALG-055009

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : ALG-055009 appears to be a best-in-class thyroid hormone receptor beta (THR-ß) agonist, which is being evaluated for the treatment of metabolic dysfunction-associated steatohepatitis (MASH).

                          Brand Name : ALG-055009

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 18, 2024

                          Lead Product(s) : ALG-055009

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Aligos expects to use the net proceeds to fund the advancement of its Phase 2a NASH, ALG-055009 study evaluating its thyroid hormone receptor beta agonist, its CAM-E candidate, ALG-000184, as well as to fund discovery and research to broaden its pipeline...

                          Brand Name : ALG-055009

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 23, 2023

                          Lead Product(s) : ALG-055009

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase I

                          Sponsor : Armistice Capital

                          Deal Size : $92.0 million

                          Deal Type : Private Placement

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                          10

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The funding will be used to conduct nonclinical and clinical studies to advance its pan-coronavirus protease inhibitor ALG-097558, a potent, pan-coronavirus small molecule inhibitor of the viral 3CL protease, into future Phase 2/3 studies.

                          Brand Name : ALG-097558

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 03, 2023

                          Lead Product(s) : ALG-097558

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : National Institute of Allergy and Infectious Diseases

                          Deal Size : $8.5 million

                          Deal Type : Funding

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