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Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"Carboplatin","moa":"||PD-1\/VEGF","graph1":"Oncology","graph2":"Approved FDF","graph3":"Summit Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Summit Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Summit Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Summit Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2024","type":"Private Placement","leadProduct":"Carboplatin","moa":"||PD-1\/VEGF","graph1":"Oncology","graph2":"Approved FDF","graph3":"Summit Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Summit Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"Summit Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Summit Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2024","type":"Financing","leadProduct":"Carboplatin","moa":"||PD-1\/VEGF","graph1":"Oncology","graph2":"Approved FDF","graph3":"Summit Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Summit Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"15","companyTruncated":"Summit Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Innovent Biologics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody","year":"2023","type":"Inapplicable","leadProduct":"Sintilimab","moa":"||PD-L1","graph1":"Oncology","graph2":"Approved FDF","graph3":"Innovent Biologics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Innovent Biologics \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Innovent Biologics \/ Inapplicable"},{"orgOrder":0,"company":"Eli Lilly","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2022","type":"Inapplicable","leadProduct":"Sintilimab","moa":"||PD-L1","graph1":"Oncology","graph2":"Phase III","graph3":"Eli Lilly","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Eli Lilly \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Eli Lilly \/ Inapplicable"},{"orgOrder":0,"company":"Waverley Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CANADA","productType":"Cytotoxic Drug","year":"2020","type":"Inapplicable","leadProduct":"Pemetrexed","moa":"TS\/DHFR\/GARFT","graph1":"Oncology","graph2":"Approved FDF","graph3":"Waverley Pharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Waverley Pharma \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Waverley Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Targovax","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"NORWAY","productType":"Microorganism","year":"2021","type":"Inapplicable","leadProduct":"Cisplatin","moa":"||GM-CSF","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Targovax","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Targovax \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Targovax \/ Inapplicable"},{"orgOrder":0,"company":"Targovax","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"NORWAY","productType":"Microorganism","year":"2020","type":"Inapplicable","leadProduct":"Cisplatin","moa":"||GM-CSF","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Targovax","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Targovax \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Targovax \/ Inapplicable"},{"orgOrder":0,"company":"Targovax","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"NORWAY","productType":"Microorganism","year":"2020","type":"Inapplicable","leadProduct":"Cisplatin","moa":"||GM-CSF","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Targovax","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Targovax \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Targovax \/ Inapplicable"},{"orgOrder":0,"company":"Polaris Group","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Large Molecule","year":"2023","type":"Inapplicable","leadProduct":"Cisplatin","moa":"||Arginine","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"Polaris Group","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Polaris Group \/ Inapplicable","highestDevelopmentStatusID":"9","companyTruncated":"Polaris Group \/ Inapplicable"},{"orgOrder":0,"company":"Ionctura","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Roginolisib","moa":"||PI3K delta","graph1":"Oncology","graph2":"Phase I","graph3":"Ionctura","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Ionctura \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Ionctura \/ Inapplicable"},{"orgOrder":0,"company":"Ionctura","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Other Small 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Molecule","year":"2024","type":"Inapplicable","leadProduct":"Bemcentinib","moa":"||AXL receptor","graph1":"Oncology","graph2":"Phase II","graph3":"BerGenBio ASA","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"BerGenBio ASA \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"BerGenBio ASA \/ Inapplicable"},{"orgOrder":0,"company":"Erkim","sponsor":"Polaris Group","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"TURKEY","productType":"Enzyme","year":"2025","type":"Agreement","leadProduct":"Pegargiminase","moa":"||Arginine","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"Erkim","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Erkim \/ Polaris Group","highestDevelopmentStatusID":"9","companyTruncated":"Erkim \/ Polaris Group"}]

Find Clinical Drug Pipeline Developments & Deals for ALIMTA

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Pemetrexed

                          Therapeutic Area : Oncology

                          Study Phase : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : The launch of Pemetrexed for Injection, 100 mg and 500 mg Single-Dose Vials, which is the generic equivalent of ALIMTA® (pemetrexed for injection) in the U.S. Market approved by the U.S. Food and Drug Administration (USFDA).

                          Product Name : Pemetrexed-Generic

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Inapplicable

                          May 27, 2022

                          Lead Product(s) : Pemetrexed

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Dr Reddy Company Banner

                          02

                          Lead Product(s) : Pemetrexed

                          Therapeutic Area : Oncology

                          Study Phase : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : EVER Pharma has received EU-wide marketing authorization of Pemetrexed EVER Pharma for the treatment of patients with malignant pleural mesothelioma and non-small cell lung cancer.

                          Product Name : Pemetrexed EVER Pharma

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Inapplicable

                          December 15, 2020

                          Lead Product(s) : Pemetrexed

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Ever Pharma CB

                          03

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Under the agreement, Polaris will holds the rights for commercialization of ADI-PEG 20 (pegargiminase). It is being evaluated in late-satge for the treatment of malignant pleural mesothelioma

                          Product Name : ADI-PEG 20

                          Product Type : Enzyme

                          Upfront Cash : Undisclosed

                          April 15, 2025

                          Lead Product(s) : Pegargiminase,Cisplatin,Pemetrexed

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Polaris Group

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          04

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : IMM2510/SYN-2510 is a PD-L1xVEGF bispecific antibody, being investigated in combination with chemotherapy in patients with advanced non-small cell lung cancer.

                          Product Name : IMM2510

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          January 14, 2025

                          Lead Product(s) : IMM2510,Cisplatin,Pemetrexed

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Dimesna (LP-300) is a cancer causing TK’s proteins and receptors inactivator, is being investigated in non-small cell lung cancer (NSCLC) in never-smokers in Taiwan.

                          Product Name : Dimesna

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 09, 2024

                          Lead Product(s) : LP-300,Carboplatin,Pemetrexed

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Summit intends to use the net proceeds to advance, in part, the clinical development of SMT112 (ivonescimab) for the treatment of EFGR-mutated non-small cell lung cancer.

                          Product Name : SMT112

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          December 09, 2024

                          Lead Product(s) : Ivonescimab,Carboplatin,Pemetrexed

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : $235.0 million

                          Deal Type : Private Placement

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                          07

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : MK-3475A (pembrolizumab, PD-1 inhibitor with berahyaluronidase alfa) in combination with chemotherapy is being investigated for adult patients with metastatic non-small cell lung cancer.

                          Product Name : Keytruda

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          November 19, 2024

                          Lead Product(s) : Pembrolizumab,Berahyaluronidase Alpha,Pemetrexed

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Dimesna (LP-300) is a cancer causing TK’s proteins and receptors inactivator, is being investigated in non-small cell lung cancer (NSCLC) in never-smokers in both Japan.

                          Product Name : Dimesna

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 19, 2024

                          Lead Product(s) : LP-300,Carboplatin,Pemetrexed

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          09

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : FDA has already approved Keytruda (Pembrolizumab) in combination with pemetrexed and platinum chemotherapy, for the first-line treatment of adult patients with unresectable advanced or metastatic MPM.

                          Product Name : Keytruda

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          November 15, 2024

                          Lead Product(s) : Pembrolizumab,Pemetrexed

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Cejemly (sugemalimab) is an anti-PD-L1 monoclonal antibody, which is indicated in combination with platinum-based chemotherapy as the first-line treatment for non-small cell lung cancer in adults.

                          Product Name : Cejemly

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          October 31, 2024

                          Lead Product(s) : Sugemalimab,Carboplatin,Pemetrexed

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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