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    [{"orgOrder":0,"company":"Regeneron Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"FDA Approves Add-on Therapy for Patients with Genetic form of Severely High Cholesterol","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Approved","country":"U.S.A","productType":"Large molecule","productStatus":"Approved","date":"April 2021","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Approved"},{"orgOrder":0,"company":"Regeneron Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Praluent\u00ae (alirocumab) Injection Receives FDA Approval to Treat Children with Genetic Form of High Cholesterol","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Approved","country":"U.S.A","productType":"Large molecule","productStatus":"Approved","date":"March 2024","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Approved"}]

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              Regeneron Pharmaceuticals

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              Praluent® (alirocumab) Injection Receives FDA Approval to Treat Children with Genetic Form of High Cholesterol

              Details:

              Praluent (alirocumab) inhibits the binding of PCSK9 to the LDL receptor. It is now approved for the treatment of pediatric patients aged 8 and older with heterozygous familial hypercholesterolemia.

              Lead Product(s): Alirocumab

              Therapeutic Area: Genetic Disease Product Name: Praluent

              Highest Development Status: Approved Product Type: Large molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable March 11, 2024

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              Regeneron Pharmaceuticals

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              FDA Approves Add-on Therapy for Patients with Genetic form of Severely High Cholesterol

              Details:

              The effectiveness and safety of Praluent were evaluated in a 12-week, double-blind, randomized trial among adult patients with HoFH. In the trial, 45 patients received 150 mg of Praluent every two weeks and 24 patients received a placebo.

              Lead Product(s): Alirocumab

              Therapeutic Area: Genetic Disease Product Name: Praluent

              Highest Development Status: Approved Product Type: Large molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable April 01, 2021

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