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Find Clinical Drug Pipeline Developments & Deals by Allegro Ophthalmics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : Luminate® (risuteganib) is a novel anti-integrin peptide that targets the multiple integrin heterodimers involved in the pathophysiology of dry AMD, it is being investigated for the treatment of intermediate, non-exudative age-related macular degenerati...

                          Product Name : Luminate

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          December 04, 2023

                          Lead Product(s) : Risuteganib

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : Pre-clinical data suggest that Luminate (risuteganib), Allegro’s lead investigational compound in retina, may simultaneously act on the angiogenic, inflammatory and mitochondrial metabolic pathways implicated in diseases, such as dry AMD.

                          Product Name : Luminate

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          October 02, 2023

                          Lead Product(s) : Risuteganib

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : These clinical data suggest that risuteganib can reverse vision loss and restore functional vision in patients with intermediate dry AMD with treatment at a 12-week interval.

                          Product Name : Luminate

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          March 08, 2021

                          Lead Product(s) : Risuteganib

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : Bausch Health, has entered into an agreement to acquire an option to purchase all ophthalmology assets of Allegro, including global rights for risuteganib (Luminate). Allegro include ALG-1007, a topical integrin regulator under investigation for treatmen...

                          Product Name : Luminate

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          September 21, 2020

                          Lead Product(s) : Risuteganib

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II

                          Sponsor : Bausch Health

                          Deal Size : $50.0 million

                          Deal Type : Acquisition

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                          05

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : The agreement provides Bausch with global rights for risuteganib, Allegro's lead investigational compound in retina, including Other ophthalmology assets such as Allegro's ALG-1007, a topical integrin regulator under investigation for the treatment of dr...

                          Product Name : Luminate

                          Product Type : Peptide

                          Upfront Cash : $10.0 million

                          September 21, 2020

                          Lead Product(s) : Risuteganib

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II

                          Sponsor : Bausch Health

                          Deal Size : $50.0 million

                          Deal Type : Acquisition

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