Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Risuteganib
Therapeutic Area : Ophthalmology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Luminate® (risuteganib) is a novel anti-integrin peptide that targets the multiple integrin heterodimers involved in the pathophysiology of dry AMD, it is being investigated for the treatment of intermediate, non-exudative age-related macular degenerati...
Product Name : Luminate
Product Type : Peptide
Upfront Cash : Inapplicable
December 04, 2023
Lead Product(s) : Risuteganib
Therapeutic Area : Ophthalmology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Risuteganib
Therapeutic Area : Ophthalmology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Pre-clinical data suggest that Luminate (risuteganib), Allegro’s lead investigational compound in retina, may simultaneously act on the angiogenic, inflammatory and mitochondrial metabolic pathways implicated in diseases, such as dry AMD.
Product Name : Luminate
Product Type : Peptide
Upfront Cash : Inapplicable
October 02, 2023
Lead Product(s) : Risuteganib
Therapeutic Area : Ophthalmology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Risuteganib
Therapeutic Area : Ophthalmology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : These clinical data suggest that risuteganib can reverse vision loss and restore functional vision in patients with intermediate dry AMD with treatment at a 12-week interval.
Product Name : Luminate
Product Type : Peptide
Upfront Cash : Inapplicable
March 08, 2021
Lead Product(s) : Risuteganib
Therapeutic Area : Ophthalmology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Risuteganib
Therapeutic Area : Ophthalmology
Study Phase : Phase II
Sponsor : Bausch Health
Deal Size : $50.0 million
Deal Type : Acquisition
Bausch Health To Acquire Option To Purchase All Ophthalmology Assets Of Allegro Ophthalmics
Details : Bausch Health, has entered into an agreement to acquire an option to purchase all ophthalmology assets of Allegro, including global rights for risuteganib (Luminate). Allegro include ALG-1007, a topical integrin regulator under investigation for treatmen...
Product Name : Luminate
Product Type : Peptide
Upfront Cash : Undisclosed
September 21, 2020
Lead Product(s) : Risuteganib
Therapeutic Area : Ophthalmology
Highest Development Status : Phase II
Sponsor : Bausch Health
Deal Size : $50.0 million
Deal Type : Acquisition
Lead Product(s) : Risuteganib
Therapeutic Area : Ophthalmology
Study Phase : Phase II
Sponsor : Bausch Health
Deal Size : $50.0 million
Deal Type : Acquisition
Bausch Health To Acquire Option To Purchase All Ophthalmology Assets Of Allegro Ophthalmics
Details : The agreement provides Bausch with global rights for risuteganib, Allegro's lead investigational compound in retina, including Other ophthalmology assets such as Allegro's ALG-1007, a topical integrin regulator under investigation for the treatment of dr...
Product Name : Luminate
Product Type : Peptide
Upfront Cash : $10.0 million
September 21, 2020
Lead Product(s) : Risuteganib
Therapeutic Area : Ophthalmology
Highest Development Status : Phase II
Sponsor : Bausch Health
Deal Size : $50.0 million
Deal Type : Acquisition