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    [{"orgOrder":0,"company":"Allyx Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"BMS-984923","moa":"","graph1":"Neurology","graph2":"Phase I","graph3":"Allyx Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Allyx Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Allyx Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Allyx Therapeutics","sponsor":"Bristol Myers Squibb","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"ALX-001","moa":"","graph1":"Neurology","graph2":"IND Enabling","graph3":"Allyx Therapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Allyx Therapeutics \/ Bristol Myers Squibb","highestDevelopmentStatusID":"5","companyTruncated":"Allyx Therapeutics \/ Bristol Myers Squibb"},{"orgOrder":0,"company":"Allyx Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"ALX-001","moa":"","graph1":"Neurology","graph2":"Phase I","graph3":"Allyx Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Allyx Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Allyx Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Allyx Therapeutics","sponsor":"Yale University","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"BMS-984923","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Allyx Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Allyx Therapeutics \/ Yale University","highestDevelopmentStatusID":"14","companyTruncated":"Allyx Therapeutics \/ Yale University"},{"orgOrder":0,"company":"Allyx Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"BMS-984923","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Allyx Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Allyx Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"Allyx Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Allyx Therapeutics","sponsor":"National Institutes of Health","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2024","type":"Funding","leadProduct":"ALX-001","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Allyx Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Allyx Therapeutics \/ National Institutes of Health","highestDevelopmentStatusID":"14","companyTruncated":"Allyx Therapeutics \/ National Institutes of Health"}]

    Find Clinical Drug Pipeline Developments & Deals by Allyx Therapeutics

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                            01

                            Allyx Therapeutics

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                            Medlab Asia & Asia Health
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                            Allyx Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : ALX-001

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : National Institutes of Health

                            Deal Size : $3.3 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Allyx Therapeutics Receives $3.3M NIH Grant for ALX-001 Clinical Studies

                            Details : The funding will support Allyx’s ALX-001, a highly-selective, first-in-class, synapse-targeted, disease-modifying oral therapy in development for Alzheimer’s disease and Parkinson’s disease.

                            Brand Name : BMS-9894923

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 15, 2024

                            Lead Product(s) : ALX-001

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : National Institutes of Health

                            Deal Size : $3.3 million

                            Deal Type : Funding

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                            02

                            Allyx Therapeutics

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                            Medlab Asia & Asia Health
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                            Allyx Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : BMS-984923

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Allyx Therapeutics Announces First Parkinson’s Disease Patient Treated with ALX-001

                            Details : ALX-001 (previously BMS-984923) is a oral silent allosteric modulator of mGluR5, which is being evaluated for the treatment of patients with parkinson’s disease.

                            Brand Name : ALX-001

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 04, 2024

                            Lead Product(s) : BMS-984923

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Allyx Therapeutics

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                            Medlab Asia & Asia Health
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                            Allyx Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : BMS-984923

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Yale University

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Allyx Announces First Alzheimer’s Disease Patient Treated with Lead Compound ALX-001

                            Details : ALX-001 (previously BMS-984923) is a oral silent allosteric modulator of mGluR5, which is being evaluated for the treatment of patients with alzheimer’s disease.

                            Brand Name : ALX-001

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 11, 2024

                            Lead Product(s) : BMS-984923

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Yale University

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Allyx Therapeutics

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                            Medlab Asia & Asia Health
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                            Allyx Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : ALX-001

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Allyx Therapeutics Announces Positive Phase 1b Data and Advances ALX-001 to Patients

                            Details : BMS-984923 (ALX-001) is a highly selective, first-in-class, synapse-targeted, disease-modifying oral therapy, which is being evaluated for the treatment of Alzheimer’s and Parkinson’s disease.

                            Brand Name : BMS-984923

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 11, 2024

                            Lead Product(s) : ALX-001

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Allyx Therapeutics

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                            Medlab Asia & Asia Health
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                            Allyx Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : ALX-001

                            Therapeutic Area : Neurology

                            Study Phase : IND Enabling

                            Sponsor : Bristol Myers Squibb

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Allyx Expands into Parkinson's Disease Research with ALX-001 Following IND Acceptance

                            Details : ALX-001 is a highly selective, first-in-class, synapse-targeted, disease-modifying oral therapy for neurodegenerative diseases. It is being evaluated for the treatment of Parkinson’s Disease.

                            Brand Name : ALX-001

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 05, 2024

                            Lead Product(s) : ALX-001

                            Therapeutic Area : Neurology

                            Highest Development Status : IND Enabling

                            Sponsor : Bristol Myers Squibb

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Allyx Therapeutics

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                            Medlab Asia & Asia Health
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                            Allyx Therapeutics

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                            Lead Product(s) : BMS-984923

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Allyx Therapeutics Lead Compound ALX-001 is Safe and Tolerable at Doses, Achieving Full Brain Target Engagemen...

                            Details : ALX-001 (previously BMS-984923) is a oral silent allosteric modulator of mGluR5, and the first-in-class compound that selectively blocks the pathogenic activation of the receptor while preserving normal glutamate signaling, being investigated for neurode...

                            Brand Name : ALX-001

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 30, 2023

                            Lead Product(s) : BMS-984923

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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