[{"orgOrder":0,"company":"Biopeutics Co. Ltd","sponsor":"Medical Center of Vienna","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"UNITED KINGDOM","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Alprostadil","moa":"EP1 receptor","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Biopeutics Co. Ltd","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Biopeutics Co. Ltd \/ Medical Center of Vienna","highestDevelopmentStatusID":"10","companyTruncated":"Biopeutics Co. Ltd \/ Medical Center of Vienna"},{"orgOrder":0,"company":"UCB Pharma S.A","sponsor":"Advanz Pharma","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"BELGIUM","productType":"Other Small Molecule","year":"2020","type":"Agreement","leadProduct":"Alprostadil","moa":"EP1 receptor","graph1":"Endocrinology","graph2":"Approved FDF","graph3":"UCB Pharma S.A","amount2":0.10000000000000001,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Endocrinology","amount2New":0.10000000000000001,"dosageForm":"Intravenous Infusion","sponsorNew":"UCB Pharma S.A \/ Advanz Pharma","highestDevelopmentStatusID":"15","companyTruncated":"UCB Pharma S.A \/ Advanz Pharma"},{"orgOrder":0,"company":"UCB Pharma S.A","sponsor":"Advanz Pharma","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"BELGIUM","productType":"Other Small Molecule","year":"2020","type":"Acquisition","leadProduct":"Alprostadil","moa":"EP1 receptor","graph1":"Endocrinology","graph2":"Approved FDF","graph3":"UCB Pharma S.A","amount2":0.10000000000000001,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Endocrinology","amount2New":0.10000000000000001,"dosageForm":"Intravenous Infusion","sponsorNew":"UCB Pharma S.A \/ Advanz Pharma","highestDevelopmentStatusID":"15","companyTruncated":"UCB Pharma S.A \/ Advanz Pharma"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Biopeutics Co. Ltd

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                          ELCC
                          Not Confirmed

                          Biopeutics Co. Ltd

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                          ELCC
                          Not Confirmed

                          Details : Eubeatline (alprostadil), is a Prostaglandin E1 agonist, which is being evaluated for the treatment of severe heart failure in adults.

                          Product Name : Eubeatline

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 18, 2023

                          Lead Product(s) : Alprostadil

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Sponsor : Medical Center of Vienna

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          ELCC
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                          ELCC
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                          Details : Advanz get the rights to a portfolio of alprostadil products including, Prostavasin, Viridal, Vasaprostan and Edex, which consists of injectable Prostaglandin E1 formulations for the treatment of erectile disfunction and peripheral arterial occlusive dis...

                          Product Name : Prostavasin

                          Product Type : Other Small Molecule

                          Upfront Cash : $96.0 million

                          April 01, 2020

                          Lead Product(s) : Alprostadil

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Approved FDF

                          Sponsor : Advanz Pharma

                          Deal Size : $96.0 million

                          Deal Type : Acquisition

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                          03

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : The alprostadil product portfolio consists of two established, niche, injectable Prostaglandin E1 formulations for the treatment of erectile disfunction and peripheral arterial occlusive disease.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : $84.0 million

                          March 06, 2020

                          Lead Product(s) : Alprostadil

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Approved FDF

                          Sponsor : Advanz Pharma

                          Deal Size : $98.0 million

                          Deal Type : Agreement

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