Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Trastuzumab Deruxtecan
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Daiichi Sankyo
Deal Size : $300.0 million
Deal Type : Licensing Agreement
Alteogen Signs Deal to Enable Subcutaneous ENHERTU® via Hybrozyme™ Tech
Details : Daiichi will acquire worldwide rights to use ALT-B4, Alteogen's novel hyaluronidase, to develop and commercialize a subcutaneous version of Enhertu (trastuzumab deruxtecan), a HER2 directed ADC.
Brand Name : Enhertu
Molecule Type : Large molecule
Upfront Cash : $20.0 million
November 10, 2024
Lead Product(s) : Trastuzumab Deruxtecan
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Daiichi Sankyo
Deal Size : $300.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Aflibercept
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Altos Biologics Files for Approval of Aflibercept Biosimilar
Details : ALT-L9 (aflibercept), biosimilar of Eylea, is a recombinant fusion protein which inhibits VEGF A. It is being evaluated in phase 3 clinical studies for the treatment of Neovascular (Wet) AMD.
Brand Name : ALT-L9
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 01, 2024
Lead Product(s) : Aflibercept
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aflibercept
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ALT-L9 (aflibercept) is a vascular endothelial growth factor (VEGF) inhibitor used to treat Neovascular (Wet) Age-Related Macular Degeneration (AMD), various types of macular edema and diabetic retinopathy.
Brand Name : ALT-L9
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 22, 2023
Lead Product(s) : Aflibercept
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery Platform
Sponsor : Sandoz B2B
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : ALT-B4 is Alteogen’s proprietary human recombinant human hyaluronidase enzyme developed utilizing the Hybrozyme™ technology. ALT-B4 can enable the large volume subcutaneous administration of drugs that are typically administered as an IV infusion.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
January 02, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery Platform
Sponsor : Sandoz B2B
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : ALT-B4,Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : Intas Pharmaceuticals
Deal Size : $109.0 million
Deal Type : Collaboration
Details : Under the terms of the agreement, Alteogen has granted worldwide rights, except for a few Asian countries, for Intas to develop two products in combination with ALT-B4.
Brand Name : ALT-B4
Molecule Type : Large molecule
Upfront Cash : $6.0 million
January 07, 2021
Lead Product(s) : ALT-B4,Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : Intas Pharmaceuticals
Deal Size : $109.0 million
Deal Type : Collaboration
Lead Product(s) : ALT-B4
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : Undisclosed
Deal Size : $3,881.0 million
Deal Type : Licensing Agreement
Alteogen Enters into a Global License Agreement with a Top Ten Pharma
Details : Under the terms of the agreement, Alteogen has granted worldwide rights for TTPC to develop multiple products in combination with ALT-B4.
Brand Name : ALT-B4
Molecule Type : Large molecule
Upfront Cash : $16.0 million
June 24, 2020
Lead Product(s) : ALT-B4
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : Undisclosed
Deal Size : $3,881.0 million
Deal Type : Licensing Agreement
Details : This is a FIH clinical trial of ALT-P7, a HER2-targeting ADC, and is a single-group, dose-escalation study designed to determine the maximum tolerated dose (MTD) and evaluate the safety of ALT-P7.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 29, 2020
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