Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : ALTO-100
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Wellcome Trust
Deal Size : $11.7 million
Deal Type : Funding
Alto Neuroscience Gets Trust Funding for ALTO-100 in Bipolar Depression
Details : The fund will used to advance the clinical development of lead candidate ALTO-100 through a Phase 2b study in patients with bipolar depression characterized by a cognitive biomarker.
Brand Name : ALTO-100
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 25, 2024
Lead Product(s) : ALTO-100
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Wellcome Trust
Deal Size : $11.7 million
Deal Type : Funding
Lead Product(s) : ALTO-100
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Alto Neuroscience Completes Enrollment in Phase 2b Study of ALTO-100 for Depression
Details : ALTO-100, targeting brain-derived-neurotrophic-factor (BDNF), which is being developed by Alto Neuroscience for the treatment of major depressive disorder and Post-traumatic stress disorder.
Brand Name : ALTO-100
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 16, 2024
Lead Product(s) : ALTO-100
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ALTO-101
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Alto Neuroscience Reports Positive Phase 1 Results for ALTO-101, a Novel PDE4 Inhibitor
Details : ALTO-101 is a novel PDE4 inhibitor, small molecule drug candidate, which is being evaluated for the treatment of cognitive impairment associated with schizophrenia.
Brand Name : ALTO-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 23, 2024
Lead Product(s) : ALTO-101
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ALTO-203
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Alto Neuroscience Begins Phase 2 Study of ALTO-203 for Major Depressive Disorder
Details : ALTO-203 is a novel small molecule histamine H3 receptor inverse agonist, which is being developed for the treatment of patients with MDD and elevated anhedonia.
Brand Name : ALTO-203
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 03, 2024
Lead Product(s) : ALTO-203
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ALTO-100
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Jefferies
Deal Size : $147.9 million
Deal Type : Public Offering
Alto Neuroscience Closes Upsized IPO with Underwriters’ Option Exercise
Details : Net proceeds will advance ALTO-100, targeting brain-derived neurotrophic factor (BDNF) for treating major depressive disorder and PTSD, developed by Alto Neuroscience.
Brand Name : ALTO-100
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 06, 2024
Lead Product(s) : ALTO-100
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Jefferies
Deal Size : $147.9 million
Deal Type : Public Offering
Lead Product(s) : ALTO-100
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Jefferies
Deal Size : $128.6 million
Deal Type : Public Offering
Alto Neuroscience Announces Pricing of Upsized Initial Public Offering
Details : Net proceeds will advance ALTO-100, targeting brain-derived neurotrophic factor (BDNF) for treating major depressive disorder and PTSD, developed by Alto Neuroscience.
Brand Name : ALTO-100
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 01, 2024
Lead Product(s) : ALTO-100
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Jefferies
Deal Size : $128.6 million
Deal Type : Public Offering
Lead Product(s) : ALTO-100
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Jefferies
Deal Size : Undisclosed
Deal Type : Public Offering
Alto Neuroscience preps IPO to Push CNS Therapies Through Clinic
Details : The net proceeds will advance clinical development of ALTO-100, targeting BDNF for treating major depressive disorder and post-traumatic stress disorder by Alto Neuroscience.
Brand Name : ALTO-100
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 16, 2024
Lead Product(s) : ALTO-100
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Jefferies
Deal Size : Undisclosed
Deal Type : Public Offering
Lead Product(s) : ALTO-300
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ALTO-300 is an investigational small molecule drug candidate, which is a melatonin receptor agonist. currently, it is being evaluated under clinical development with patients suffering related to major depressive disorder.
Brand Name : ALTO-300
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 04, 2023
Lead Product(s) : ALTO-300
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ALTO-100
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : InVivium Capital
Deal Size : $45.0 million
Deal Type : Series C Financing
Alto Neuroscience Closes $45 Million in Oversubscribed Series C Financing
Details : The funds will be used to support ongoing and planned clinical development of the Company's late-stage CNS product candidates, including ALTO-100 currently in Phase II for Major Depressive Disorder.
Brand Name : ALTO-100
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 21, 2023
Lead Product(s) : ALTO-100
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : InVivium Capital
Deal Size : $45.0 million
Deal Type : Series C Financing
Lead Product(s) : ALTO-100
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The Phase 2 study leveraged Alto’s Precision Psychiatry Platform™ to identify likely drug responders based on an understanding of biological heterogeneity in depression and ALTO-100’s novel mechanism.
Brand Name : ALTO-100
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 26, 2023
Lead Product(s) : ALTO-100
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
LOOKING FOR A SUPPLIER?