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Find Clinical Drug Pipeline Developments & Deals for Alvocidib

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01

ICHH-25
Not Confirmed
ICHH-25
Not Confirmed

Details : Zella 201 is a biomarker-driven study of alvocidib followed by cytarabine and mitoxantrone in patients with relapsed/refractory MCL-1 dependent acute myeloid leukemia. Data presented will include findings from an exploratory cohort of newly diagnosed, hi...

Product Name : Flavopiridol

Product Type : Small molecule

Upfront Cash : Not Applicable

November 06, 2020

Lead Product(s) : Alvocidib,Mitoxantrone,Cytarabine

Therapeutic Area : Oncology

Highest Development Status : Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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02

ICHH-25
Not Confirmed
ICHH-25
Not Confirmed

Details : Updated findings from the Phase 1, dose-escalation, safety and biomarker study of alvocidib followed by cytarabine and daunorubicin (7+3) induction therapy showed encouraging clinical activity and a tolerable safety profile in adults with newly diagnosed...

Product Name : Undisclosed

Product Type : Small molecule

Upfront Cash : Not Applicable

June 12, 2020

Lead Product(s) : Alvocidib,Cytarabine

Therapeutic Area : Oncology

Highest Development Status : Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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03

ICHH-25
Not Confirmed
ICHH-25
Not Confirmed

Details : First patient has been dosed with a one-hour dosing schedule for investigational agent alvocidib, a potent CDK9 inhibitor, administered in sequence after azacitidine, in the expansion of the Phase 1b/2 Zella 102 study in patients with myelodysplastic syn...

Product Name : Undisclosed

Product Type : Small molecule

Upfront Cash : Not Applicable

May 14, 2020

Lead Product(s) : Alvocidib,Decitabine

Therapeutic Area : Oncology

Highest Development Status : Phase I/ Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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04

ICHH-25
Not Confirmed
ICHH-25
Not Confirmed

Details : The open-label, randomized study has two parts and will evaluate the safety and efficacy of alvocidib in monotherapy or in combination with low-dose cytarabine.

Product Name : Undisclosed

Product Type : Small molecule

Upfront Cash : Not Applicable

January 15, 2020

Lead Product(s) : Alvocidib,Cytarabine

Therapeutic Area : Oncology

Highest Development Status : Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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