Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Study Phase : Phase II/ Phase III
Sponsor : AstraZeneca
Deal Size : $1,050.0 million
Deal Type : Acquisition
AstraZeneca Closes Acquisition of Amolyt Pharma
Details : Through the acquisition, AstraZeneca leverages the AZP-3601 (neboparatide), peptide agonist of the PTH1 receptor. Currently, being evaluated for the treatment of Chronic Hypoparathyroidism.
Product Name : AZP-3601
Product Type : Peptide
Upfront Cash : $800.0 million
July 15, 2024
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Highest Development Status : Phase II/ Phase III
Sponsor : AstraZeneca
Deal Size : $1,050.0 million
Deal Type : Acquisition
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Study Phase : Phase III
Sponsor : AstraZeneca
Deal Size : $1,050.0 million
Deal Type : Acquisition
Amolyt Pharma Enters into Definitive Agreement to be Acquired by AstraZeneca
Details : AstraZeneca leverages AZP-3601 (neboparatide), a peptide agonist of the PTH1 receptor, currently in Phase III for treating chronic hypoparathyroidism and related endocrine diseases.
Product Name : AZP-3601
Product Type : Peptide
Upfront Cash : $800.0 million
March 14, 2024
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Highest Development Status : Phase III
Sponsor : AstraZeneca
Deal Size : $1,050.0 million
Deal Type : Acquisition
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Amolyt Pharma Granted FDA Fast Track for Eneboparatide in Hypoparathyroidism
Details : AZP-3601 (neboparatide) is a peptide agonist of the PTH1 receptor. Currently, being evaluated in the Phase III for Chronic Hypoparathyroidism, Endocrine System Diseases, and Parathyroid Diseases.
Product Name : AZP-3601
Product Type : Peptide
Upfront Cash : Inapplicable
February 05, 2024
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : Sofinnova Partners
Deal Size : $138.0 million
Deal Type : Series C Financing
Details : Amolyt plans to use the proceeds to advance its pipeline of therapeutics for rare endocrine and related disorders, including AZP-3601, now known as eneboparatide, for the treatment of hypoparathyroidism, and AZP-3813 for the treatment of acromegaly.
Product Name : AZP-3601
Product Type : Peptide
Upfront Cash : Undisclosed
June 01, 2023
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : Sofinnova Partners
Deal Size : $138.0 million
Deal Type : Series C Financing
Lead Product(s) : AZP-3813
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : PeptiDream
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AZP-3813, a peptide GHR antagonist, is being developed as a potential treatment for acromegaly to be used in combination with somatostatin analogues (SSAs) for patients who do not adequately respond to SSAs alone.
Product Name : AZP-3813
Product Type : Peptide
Upfront Cash : Inapplicable
May 06, 2023
Lead Product(s) : AZP-3813
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : PeptiDream
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AZP-3601 (eneboparatide) targets PTH receptor to safely produce sustained blood levels of calcium and thereby manage the symptoms of hypoparathyroidism, and to limit urine calcium excretion by restoring calcium reabsorption by the kidney, preventing chro...
Product Name : AZP-3601
Product Type : Peptide
Upfront Cash : Inapplicable
February 05, 2023
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AZP-3601 is an investigational therapeutic peptide designed to target a specific conformation of the parathyroid hormone (PTH) receptor to safely produce sustained and stable levels of calcium in the blood and thereby manage the symptoms of hypoparathyro...
Product Name : AZP-3601
Product Type : Peptide
Upfront Cash : Inapplicable
December 10, 2022
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Amolyt Pharma to Present Full Phase 2a Data on AZP-3601 at Upcoming Conferences
Details : AZP-3601 is an investigational therapeutic peptide designed to target a specific conformation of the parathyroid hormone (PTH) receptor to safely produce sustained and stable levels of calcium in the blood and thereby manage the symptoms of hypoparathyro...
Product Name : AZP-3601
Product Type : Peptide
Upfront Cash : Inapplicable
December 10, 2022
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AZP-3601 is an investigational therapeutic peptide designed to target a specific conformation of the parathyroid hormone (PTH) receptor to safely produce sustained and stable levels of calcium in the blood and thereby manage the symptoms of hypoparathyro...
Product Name : AZP-3601
Product Type : Peptide
Upfront Cash : Inapplicable
December 09, 2022
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AZP-3601, a long-acting PTH analog as a potential treatment for hypoparathyroidism, and AZP-3813, a peptide growth hormone receptor antagonist for the potential treatment of acromegaly.
Product Name : AZP-3601
Product Type : Peptide
Upfront Cash : Inapplicable
July 09, 2022
Lead Product(s) : Eneboparatide
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable