Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Alisertib,Anastrozole
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Puma Starts ALISCA™-Breast1 Trial for Alisertib in HR+, HER2- Breast Cancer
Details : MLN8237 (alisertib) is a high affinity, selective, orally bioavailable inhibitors of Aurora A. It is being developed for the treatment of HER2-negative, HR-positive metastatic breast cancer.
Product Name : MLN8237
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 20, 2024
Lead Product(s) : Alisertib,Anastrozole
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Alisertib,Anastrozole
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Puma Biotechnology Allowed to Proceed Under IND for Alisertib in Metastatic Breast Cancer
Details : MLN8237 (alisertib) is a high affinity, selective, orally bioavailable inhibitors of Aurora A. It is being developed for the treatment of HER2-negative, HR-positive metastatic breast cancer.
Product Name : MLN8237
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 20, 2024
Lead Product(s) : Alisertib,Anastrozole
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Alisertib,Anastrozole
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : MLN8237 (alisertib) is a high affinity, selective, orally bioavailable inhibitors of Aurora A. It is being developed for the treatment of HER2-negative, HR-positive metastatic breast cancer.
Product Name : MLN8237
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 12, 2023
Lead Product(s) : Alisertib,Anastrozole
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Onapristone,Anastrozole
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ONA-XR (onapristone) is a selective progesterone receptor (PR) antagonist designed to block both ligand dependent and ligand-independent activity of PR which downregulates cancer stem cellmobilization, and blocking immune evasion.
Product Name : ONA-XR
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 02, 2023
Lead Product(s) : Onapristone,Anastrozole
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Abemaciclib,Anastrozole
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Verzenio (abemaciclib) is a small molecule CDK4/CD6 inhibitor which is under phase 3 clinical development in combination with anastrozole for the treatment of post-menopausal patients with HR+/HER2-, advanced or metastatic breast cancer.
Product Name : Verzenio
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 12, 2023
Lead Product(s) : Abemaciclib,Anastrozole
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ribociclib,Anastrozole
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details :
Product Name : Kisqali
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 27, 2023
Lead Product(s) : Ribociclib,Anastrozole
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Testosterone Undecanoate,Anastrozole
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CLAR-121 is combination of testosterone undecanoate (natural ligand for the androgen receptor and anastrozole delivered by a subcutaneous implant for treatment of AR-mediated inflammatory breast disease that predominantly affects women.
Product Name : Jatenzo
Product Type : Hormone
Upfront Cash : Inapplicable
October 05, 2022
Lead Product(s) : Testosterone Undecanoate,Anastrozole
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ribociclib,Anastrozole
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Kisqali (ribociclib) is the only CDK4/6 inhibitor with proven overall survival benefit across all three pivotal Phase III advanced breast cancer trials and is recognized as the only CDK4/6i with overall survival benefit in first-line HR+/HER2- advanced b...
Product Name : Kisqali
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 12, 2022
Lead Product(s) : Ribociclib,Anastrozole
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Onapristone,Anastrozole
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Context Therapeutics Announces Poster Presentation at the Upcoming 2022 ASCO Annual Meeting
Details : Lead clinical-stage oral progesterone receptor (PR) antagonist ONA-XR (onapristone extended release) demonstrates monotherapy clinical activity in advanced granulosa cell tumor of the ovary.
Product Name : ONA-XR
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 05, 2022
Lead Product(s) : Onapristone,Anastrozole
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Testosterone,Anastrozole
Therapeutic Area : Immunology
Study Phase : Undisclosed
Sponsor : Clarus Therapeutics
Deal Size : $11.2 million
Deal Type : Licensing Agreement
Clarus Therapeutics and HavaH Therapeutics Announce Licensing Agreement
Details :
Product Name : CLAR-121
Product Type : Hormone
Upfront Cash : $0.5 million
May 25, 2021
Lead Product(s) : Testosterone,Anastrozole
Therapeutic Area : Immunology
Highest Development Status : Undisclosed
Sponsor : Clarus Therapeutics
Deal Size : $11.2 million
Deal Type : Licensing Agreement