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Find Clinical Drug Pipeline Developments & Deals for ANEB 001
ANEB-001, a potent, small molecule cannabinoid receptor antagonist, under development to address the unmet medical need for a specific antidote for acute Cannabinoid Intoxication.
ANEB-001, is an orally bioavailable, readily absorbed a potent, small molecule cannabinoid receptor antagonist, to address the unmet medical need for a specific antidote for Acute Cannabinoid Intoxication.
Treatment of subjects with 10 mg or 30 mg ANEB-001 led to significant and sustained reductions in the visual analog scale (VAS) feeling high score (p < 0.001), improvement in the VAS alertness scale (p < 0.01), and a reduction in THC-induced body sway, compared to placebo.
The data demonstrated a highly statistically significant reduction in key symptoms of ACI, with only 10% of subjects in the 50 mg ANEB-001 group and 30% in the 100 mg group reporting feeling high compared to 75% of subjects in the placebo group (p < 0.001).
ANEB-001 is a potent, small molecule cannabinoid receptor antagonist, to address the unmet medical need for a specific antidote for cannabinoid intoxication.
ANEB-001, is a competitive CB1 antagonist with a high affinity for the human CB1 receptor, is being developed with the intent to quickly and effectively reverse the negative effects of cannabinoid intoxication within one hour of administration.