[{"orgOrder":0,"company":"AnGes","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2020","type":"Not Applicable","leadProduct":"DNA vaccine","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Undisclosed","graph3":"AnGes","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"","sponsorNew":"AnGes \/ Not Applicable","highestDevelopmentStatusID":"1","companyTruncated":"AnGes \/ Not Applicable"},{"orgOrder":0,"company":"AnGes","sponsor":"Emendo Biotherapeutics","pharmaFlowCategory":"D","therapeuticArea":"Rare Diseases and Disorders","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Series B Financing","leadProduct":"OMNI nuclease","moa":"","graph1":"Rare Diseases and Disorders","graph2":"Undisclosed","graph3":"AnGes","amount2":0.059999999999999998,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Rare Diseases","amount2New":0.059999999999999998,"dosageForm":"","sponsorNew":"AnGes \/ AnGes","highestDevelopmentStatusID":"1","companyTruncated":"AnGes \/ AnGes"},{"orgOrder":0,"company":"AnGes","sponsor":"Fresh Tracks Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2020","type":"Collaboration","leadProduct":"AG0302-COVID19","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase I\/ Phase II","graph3":"AnGes","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"","sponsorNew":"AnGes \/ Brickell Biotech","highestDevelopmentStatusID":"7","companyTruncated":"AnGes \/ Brickell Biotech"},{"orgOrder":0,"company":"AnGes","sponsor":"Er-Kim","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Licensing Agreement","leadProduct":"Beperminogene Perplasmid","moa":"","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved","graph3":"AnGes","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"","sponsorNew":"AnGes \/ Er-Kim","highestDevelopmentStatusID":"12","companyTruncated":"AnGes \/ Er-Kim"},{"orgOrder":0,"company":"AnGes","sponsor":"Emendo Biotherapeutics","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Acquisition","leadProduct":"EMD-101","moa":"","graph1":"Genetic Disease","graph2":"Preclinical","graph3":"AnGes","amount2":0.25,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0.25,"dosageForm":"","sponsorNew":"AnGes \/ AnGes","highestDevelopmentStatusID":"4","companyTruncated":"AnGes \/ AnGes"},{"orgOrder":0,"company":"AnGes","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2020","type":"Not Applicable","leadProduct":"AG0302-COVID19","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase II\/ Phase III","graph3":"AnGes","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"AnGes \/ Not Applicable","highestDevelopmentStatusID":"9","companyTruncated":"AnGes \/ Not Applicable"},{"orgOrder":0,"company":"AnGes","sponsor":"Eiger BioPharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Partnership","leadProduct":"Lonafarnib","moa":"","graph1":"Genetic Disease","graph2":"Approved","graph3":"AnGes","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Inhalation","sponsorNew":"AnGes \/ AnGes","highestDevelopmentStatusID":"12","companyTruncated":"AnGes \/ AnGes"},{"orgOrder":0,"company":"AnGes","sponsor":"Eiger BioPharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Lonafarnib","moa":"","graph1":"Genetic Disease","graph2":"Approved","graph3":"AnGes","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Capsule","sponsorNew":"AnGes \/ AnGes","highestDevelopmentStatusID":"12","companyTruncated":"AnGes \/ AnGes"}]

Find Clinical Drug Pipeline Developments & Deals by AnGes

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          BIO Partnering at JPM
                          Not Confirmed
                          BIO Partnering at JPM
                          Not Confirmed

                          Details : Zokinvy (lonafarnib) is a first-in-class farnesyltransferase inhibitor. It is approved for Hutchinson- Gilford Progeria Syndrome and Processing-Deficient Progeroid Laminopathies.

                          Brand Name : Zokinvy

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          January 18, 2024

                          Lead Product(s) : Lonafarnib

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved

                          Recipient : Eiger BioPharmaceuticals

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          BIO Partnering at JPM
                          Not Confirmed
                          BIO Partnering at JPM
                          Not Confirmed

                          Details : Under the terms of the agreement, AnGes is responsible for obtaining and maintaining regulatory approval for Zokinvy (lonafarnib) in Japan and will be the exclusive partner for distribution and commercialization.

                          Brand Name : Zokinvy

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          May 10, 2022

                          Lead Product(s) : Lonafarnib

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Approved

                          Recipient : Eiger BioPharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          03

                          BIO Partnering at JPM
                          Not Confirmed
                          BIO Partnering at JPM
                          Not Confirmed

                          Details : EmendoBio to operate as an independent subsidiary of AnGes with full access to AnGes’ global development resources to accelerate development and manufacturing capabilities for EmendoBio’s dual OMNI™ genome editing technology platforms.

                          Brand Name : EMD-101

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          December 15, 2020

                          Lead Product(s) : EMD-101

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Recipient : Emendo Biotherapeutics

                          Deal Size : $250.0 million

                          Deal Type : Acquisition

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                          04

                          BIO Partnering at JPM
                          Not Confirmed
                          BIO Partnering at JPM
                          Not Confirmed

                          Details : The trials involve 500 people. A group of 250 people will be vaccinated twice with AG0302-COVID19, in an interval of two weeks; the second group of 250 people twice with an interval of four weeks.

                          Brand Name : AG0302-COVID19

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          December 08, 2020

                          Lead Product(s) : AG0302-COVID19

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          BIO Partnering at JPM
                          Not Confirmed
                          BIO Partnering at JPM
                          Not Confirmed

                          Details : Under the terms of the agreement, Er-Kim will have the exclusive rights to commercialize Collategene® in Turkey after obtaining the necessary regulatory approvals.

                          Brand Name : Collategene

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          October 08, 2020

                          Lead Product(s) : Beperminogene Perplasmid

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved

                          Sponsor : Er-Kim

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          06

                          BIO Partnering at JPM
                          Not Confirmed
                          BIO Partnering at JPM
                          Not Confirmed

                          Details : AnGes is currently conducting Phase 1/2 clinical studies with its vaccine candidate in Japan, and the results from these studies will guide AnGes’ and Brickell’s global development efforts of this novel vaccine candidate.

                          Brand Name : AG0302-COVID19

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          September 08, 2020

                          Lead Product(s) : AG0302-COVID19

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Fresh Tracks Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          07

                          BIO Partnering at JPM
                          Not Confirmed
                          BIO Partnering at JPM
                          Not Confirmed

                          Details : The company is working on the developement of a prophylactic DNA vaccine for COVID-19 using plasmid DNA production technology.

                          Brand Name : Undisclosed

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          March 05, 2020

                          Lead Product(s) : DNA vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Undisclosed

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          BIO Partnering at JPM
                          Not Confirmed
                          BIO Partnering at JPM
                          Not Confirmed

                          Details : The funding will accelerate novel OMNI gene editing platform into a broad therapeutic product pipeline.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          January 15, 2020

                          Lead Product(s) : OMNI nuclease

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Undisclosed

                          Recipient : Emendo Biotherapeutics

                          Deal Size : $61.0 million

                          Deal Type : Series B Financing

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