Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : ELI-002 7P
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Elicio Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Elicio Therapeutics Announces Completion of Merger with Angion Biomedica
Details : The combined company will focus on the advancement of its clinical development program, ELI-002, a therapeutic cancer vaccine designed with Elicio’s proprietary lymph node-targeting AMP technology, being evaluated in patients with mKRAS-driven solid tu...
Product Name : ELI-002 7P
Product Type : Vaccine
Upfront Cash : Undisclosed
January 06, 2023
Lead Product(s) : ELI-002 7P
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Elicio Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : ANG-3070
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ANG-3070, an oral tyrosine kinase inhibitor (TKI), in patients with primary proteinuric kidney diseases, specifically focal segmental glomerulosclerosis (FSGS) and immunoglobulin A nephropathy (IgAN).
Product Name : ANG-3070
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 29, 2022
Lead Product(s) : ANG-3070
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ANG-3070
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Angion Announces Phase 1b Trial of ANG-3070 in Patients with Idiopathic Pulmonary Fibrosis
Details : ANG-3070 is an oral tyrosine kinase inhibitor targeting platelet-derived growth factor receptor alpha and beta and Discoidin Domain Receptors 1 and 2 (DDR1 and DDR2), tyrosine kinase receptors linked to the development of fibrosis in the kidneys and lung...
Product Name : ANG-3070
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 16, 2022
Lead Product(s) : ANG-3070
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : Vifor Pharma
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The overall safety profile of ANG-3777 in this trial was consistent with the overall experience in its clinical development program and consistent with the published literature in this patient population.
Product Name : ANG-3777
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 26, 2021
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : Vifor Pharma
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Terevalefim
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Vifor Pharma
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The results from the Phase 2 GUARD trial of Angion’s ANG-3777 in patients undergoing cardiac surgery involving cardiopulmonary bypass at risk for developing acute kidney injury.
Product Name : ANG-3777
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 12, 2021
Lead Product(s) : Terevalefim
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Vifor Pharma
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ANG-3777 is a small molecule designed to mimic the biological activity of hepatocyte growth factor (HGF), trial did not meet its primary endpoint of percentage increase in serum creatinine based upon the area under the curve (AUC).
Product Name : ANG-3777
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 12, 2021
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ANG-3070
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The presentation describes preclinical data from a study of ANG-3070 in a mouse unilateral ureteral obstruction (UUO) model, a well-established model for obstructive renal disease.
Product Name : ANG-3070
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 11, 2021
Lead Product(s) : ANG-3070
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ANG-3070
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The Phase 1 study was a randomized, double-blind, and placebo-controlled study in healthy volunteers conducted in Australia to assess the safety, tolerability, pharmacokinetics, and food effect of ANG-3070 dosed orally.
Product Name : ANG-3070
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 08, 2021
Lead Product(s) : ANG-3070
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : Phase III
Sponsor : Vifor Pharma
Deal Size : $30.0 million
Deal Type : Licensing Agreement
Vifor Pharma and Angion Sign License Agreement for ANG-3777 in Nephrology Indications
Details : Under the terms of the agreement, Vifor Pharma will receive an exclusive global license, excluding China, Taiwan, Hong Kong and Macau, for all ANG-3777 nephrology indications.
Product Name : ANG-3777
Product Type : Other Small Molecule
Upfront Cash : $30.0 million
September 11, 2020
Lead Product(s) : Terevalefim
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : Phase III
Sponsor : Vifor Pharma
Deal Size : $30.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Terevalefim
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The Phase 2 trial is a multicenter, prospective, randomized, double-blind, placebo-controlled trial to assess safety and efficacy of ANG-3777 in patients hospitalized with confirmed COVID-19 pneumonia.
Product Name : ANG-3777
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 07, 2020
Lead Product(s) : Terevalefim
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable