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    [{"orgOrder":0,"company":"Anthos Therapeutics","sponsor":"Lonza Group","pharmaFlowCategory":"D","therapeuticArea":"Hematology","country":"SWITZERLAND","productType":"Large molecule","year":"2020","type":"Partnership","leadProduct":"Abelacimab","moa":"Factor XI","graph1":"Hematology","graph2":"Undisclosed","graph3":"Anthos Therapeutics","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"","sponsorNew":"Anthos Therapeutics \/ Anthos Therapeutics","highestDevelopmentStatusID":"1","companyTruncated":"Anthos Therapeutics \/ Anthos Therapeutics"},{"orgOrder":0,"company":"Anthos Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"Abelacimab","moa":"Factor XI","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Anthos 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\/ Not Applicable"},{"orgOrder":0,"company":"Anthos Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Abelacimab","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Anthos Therapeutics","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Anthos Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Anthos Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Anthos Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Abelacimab","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Anthos 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    Find Clinical Drug Pipeline Developments & Deals by Anthos Therapeutics

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                            01

                            Anthos Therapeutics

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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Anthos Highlights Abelacimab’s Bleeding Reduction Over Rivaroxaban in AZALEA-TIMI 71

                            Details : MAA868 (abelacimab) is a highly selective, mAb designed to induce hemostasis-sparing anticoagulation through Factor XI inhibition, in patients with Atrial Fibrillation with high risk of stroke.

                            Brand Name : MAA868

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            November 16, 2024

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Anthos Therapeutics

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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Anthos Therapeutics Shares New Data on Abelacimab's Low Bleeding Risk

                            Details : MAA868 (abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition.

                            Brand Name : MAA868

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 02, 2024

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Anthos Therapeutics

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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Anthos Announces 84% Transition to Abelacimab in AZALEA-TIMI 71 Study for AFib at a Stroke

                            Details : MAA868 (abelacimab) is a highly selective, monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition, in patients with Atrial Fibrillation.

                            Brand Name : MAA868

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 06, 2024

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Anthos Therapeutics

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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Anthos Therapeutics' Novel Dual-Acting Factor XI/XIa Inhibitor, Abelacimab 150 mg, Demonstrated a 67% Reductio...

                            Details : MAA868 (abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition.

                            Brand Name : MAA868

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            November 13, 2023

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Anthos Therapeutics

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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Memphis Seniors with a History of Atrial Fibrillation Joining New Research Study

                            Details : MAA868 (abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition.

                            Brand Name : MAA868

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 20, 2023

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Anthos Therapeutics

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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Atrial Fibrillation Study with Abelacimab Stopped Early by the Data Monitoring Committee Due to an Overwhelmin...

                            Details : MAA868 (abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition, which is investigated for patients with atrial fibrillation at moderate-to-high risk ...

                            Brand Name : MAA868

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 18, 2023

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Anthos Therapeutics

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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Itreas

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Regulatory Authorities in China and Japan Approve Clinical Trials for Anthos Therapeutics' Dual-Acting Factor ...

                            Details : MAA868 (abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition.

                            Brand Name : MAA868

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 08, 2023

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Itreas

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Anthos Therapeutics

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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            First Patient Enrolled in Phase 3 Trial Evaluating Abelacimab in High-Risk Patients with Atrial Fibrillation D...

                            Details : MAA868 (Abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition. It has received FDA Fast-Track Designations for the prevention systemic embolism with...

                            Brand Name : MAA868

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            January 03, 2023

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Anthos Therapeutics

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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Anthos Therapeutics Launches Second Phase 3 Clinical Trial of Its Dual-acting Factor XI Inhibitor, Abelacimab

                            Details : MAA868 (abelacimab) is dual-acting fully human monoclonal antibody targeting both Factor XI and Factor XIa with high affinity and selectivity, targets active domain of Factor XI, demonstrating dual inhibitory activity against both Factor XI and its activ...

                            Brand Name : MAA868

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            August 25, 2022

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Anthos Therapeutics

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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Four New Sets of Pre-Clinical Data Further Expands the Evidence Supporting Abelacimab

                            Details : Abelacimab is a novel, highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            July 13, 2022

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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