Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $3,075.0 million
Deal Type : Acquisition
Novartis to Acquire Anthos Therapeutics for USD 925 Million Upfront
Details : Through the acquisition, Novartis will strengthen its cardiovascular portfolio with Anthos' MAA868 (abelacimab), a potential monoclonal antibody for the treatment of atrial fibrillation.
Product Name : MAA868
Product Type : Antibody
Upfront Cash : $925.0 million
February 11, 2025
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $3,075.0 million
Deal Type : Acquisition
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Anthos Highlights Abelacimab’s Bleeding Reduction Over Rivaroxaban in AZALEA-TIMI 71
Details : MAA868 (abelacimab) is a highly selective, mAb designed to induce hemostasis-sparing anticoagulation through Factor XI inhibition, in patients with Atrial Fibrillation with high risk of stroke.
Product Name : MAA868
Product Type : Large molecule
Upfront Cash : Not Applicable
November 16, 2024
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Anthos Therapeutics Shares New Data on Abelacimab's Low Bleeding Risk
Details : MAA868 (abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition.
Product Name : MAA868
Product Type : Large molecule
Upfront Cash : Not Applicable
September 02, 2024
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Anthos Announces 84% Transition to Abelacimab in AZALEA-TIMI 71 Study for AFib at a Stroke
Details : MAA868 (abelacimab) is a highly selective, monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition, in patients with Atrial Fibrillation.
Product Name : MAA868
Product Type : Large molecule
Upfront Cash : Not Applicable
June 06, 2024
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MAA868 (abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition.
Product Name : MAA868
Product Type : Large molecule
Upfront Cash : Not Applicable
November 13, 2023
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Memphis Seniors with a History of Atrial Fibrillation Joining New Research Study
Details : MAA868 (abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition.
Product Name : MAA868
Product Type : Large molecule
Upfront Cash : Not Applicable
September 20, 2023
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MAA868 (abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition, which is investigated for patients with atrial fibrillation at moderate-to-high risk ...
Product Name : MAA868
Product Type : Large molecule
Upfront Cash : Not Applicable
September 18, 2023
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : Itreas
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MAA868 (abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition.
Product Name : MAA868
Product Type : Large molecule
Upfront Cash : Not Applicable
June 08, 2023
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : Itreas
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MAA868 (Abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition. It has received FDA Fast-Track Designations for the prevention systemic embolism with...
Product Name : MAA868
Product Type : Large molecule
Upfront Cash : Not Applicable
January 03, 2023
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : MAA868 (abelacimab) is dual-acting fully human monoclonal antibody targeting both Factor XI and Factor XIa with high affinity and selectivity, targets active domain of Factor XI, demonstrating dual inhibitory activity against both Factor XI and its activ...
Product Name : MAA868
Product Type : Large molecule
Upfront Cash : Not Applicable
August 25, 2022
Lead Product(s) : Abelacimab
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable