Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : B244
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Maruho
Deal Size : Undisclosed
Deal Type : Licensing Agreement
AOB Pharma Enters License Agreement for Topical Biologic B244 in Japan
Details : The agreement aims to develop AOB's topical biologic B244, preparing for global Phase 3 trials, a therapeutic for dermatological conditions like Atopic Dermatitis and pruritus.
Brand Name : B244
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 05, 2024
Lead Product(s) : B244
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Maruho
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : B244
Therapeutic Area : Dermatology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
AOBiome Therapeutics Granted Composition of Matter Patent for its Clinical Candidate B244
Details : B244 platform is a patented, proprietary, topical formulation. Once deployed, B244 produces nitric oxide, a signaling molecule known to regulate inflammation and vasodilation. It has shown clinical significance for atopic dermatitis and associated prurit...
Brand Name : B244
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 06, 2023
Lead Product(s) : B244
Therapeutic Area : Dermatology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : B244
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Company’s lead product candidate, B244, a live topical biotherapeutic, subject Phase 2b trial for Treatment of Pruritus associated with Atopic Dermatitis successfully completes its recruitment goal.
Brand Name : B244
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 16, 2021
Lead Product(s) : B244
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ammonia Oxidizing Bacteria
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : A total of 30 subjects used a cream containing metabolically inactive AOB twice a day for 2 weeks. Continuing the historically strong safety profile of applied AOB, the cream formulation was well-tolerated by the subjects.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 17, 2021
Lead Product(s) : Ammonia Oxidizing Bacteria
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : B244
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
AOBiome Reports Successful Clinical Trials in Pruritus Associated with Atopic Dermatitis
Details : The adult trial was a double blind, placebo controlled, multicenter, Phase 2a study of B244, a first-in-class, topical formulation of beneficial ammonia oxidizing bacteria, delivered as a topical spray twice daily for 28 days.
Brand Name : B244
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 30, 2020
Lead Product(s) : B244
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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