Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Apollomics Announces Positive Data for Vebreltinib in MET Fusion Tumors in Phase 2
Details : APL-101 (vebreltinib) is a small-molecule inhibitor that targets MET tyrosine kinase activity. It is being developed for the treatment of MET Exon 14 skip non-small cell lung cancer.
Brand Name : APL-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 13, 2024
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Canaccord Genuity
Deal Size : $6.0 million
Deal Type : Private Placement
Apollomics Announces Private Placement Financing and Addition to Board of Directors
Details : Apollomics plans to use proceeds to fund pipeline programs including APL-101, a selective c-Met inhibitor, for treating non-small cell lung cancer and tumors with c-Met alterations.
Brand Name : APL-101
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 08, 2024
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Canaccord Genuity
Deal Size : $6.0 million
Deal Type : Private Placement
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Study Phase : Phase II
Recipient : Predicine
Deal Size : Undisclosed
Deal Type : Collaboration
Predicine Collaborates with Apollomics for Lung Cancer Companion Diagnostic
Details : The collaboration seeks to develop PredicineCARE, a blood cfDNA NGS assay to identify NSCLC patients who may benefit from therapy with APL-101 (vebreltinib), a small molecule c-Met inhibitor.
Brand Name : APL-101
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 05, 2024
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : Predicine
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Uproleselan,Mitoxantrone,Etoposide
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Apollomics Completes Enrollment in Phase 3 Study Of Uproleselan
Details : APL-106 (uproleselan), an E-selectin antagonist, is in Phase 3 trials for relapsed/refractory acute myeloid leukemia (AML).
Brand Name : APL-106
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 03, 2024
Lead Product(s) : Uproleselan,Mitoxantrone,Etoposide
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : APL-101 (vebreltinib) is a small-molecule inhibitor that targets MET tyrosine kinase activity. It is being developed for the treatment of MET Exon 14 skip non-small cell lung cancer.
Brand Name : APL-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 16, 2023
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : APL-101 (vebreltinib) is a highly specific cMet inhibitor which is under phase 2 clinical development in non-small cell lung cancer and other solid tumors with MET dysregulations.
Brand Name : APL-101
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 31, 2023
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Maxpro Capital Acquisition Corp.
Deal Size : $23.6 million
Deal Type : Private Placement
Details : Apollomics will use the financing to advance APL-101 (vebreltinib), a highly specific cMet inhibitor, in non-small cell lung cancer and other solid tumors with cMet dysregulation.
Brand Name : APL-101
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 30, 2023
Lead Product(s) : Vebreltinib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Maxpro Capital Acquisition Corp.
Deal Size : $23.6 million
Deal Type : Private Placement
Lead Product(s) : Uproleselan,Mitoxantrone,Etoposide
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The primary endpoint of APL-106 is overall survival and Secondary outcome measures the rate and duration of remission, and whether APL-106 can reduce the rate of oral mucositis, a chemotherapy-related side effect.
Brand Name : APL-106
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 22, 2021
Lead Product(s) : Uproleselan,Mitoxantrone,Etoposide
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Uproleselan
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : APL-106 (uproleselan injection) is an innovative drug discovered and developed by GlycoMimetics. Apollomics licensed uproleselan from GlycoMimetics, and Apollomics has the rights to clinical development, production and commercial sales in the Greater Chi...
Brand Name : APL-106
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 22, 2021
Lead Product(s) : Uproleselan
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Apollomics, Inc. Doses First Patient in A Phase I Clinical Trial of APL-102
Details : APL-102 has also shown favorable preclinical pharmacokinetic (PK) and safety profiles with no serious off-target activity observed. APL-102 has the potential to be used as a single agent or in combination with other oncology agents.
Brand Name : APL-102
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 10, 2021
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