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    [{"orgOrder":0,"company":"Arbor Biotechnologies, Inc","sponsor":"Vor Biopharma","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Collaboration","leadProduct":"Engineered hematopoietic stem cell","moa":"CD33","graph1":"Oncology","graph2":"Preclinical","graph3":"Arbor Biotechnologies, Inc","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Arbor Biotechnologies, Inc \/ Vor Biopharma","highestDevelopmentStatusID":"4","companyTruncated":"Arbor Biotechnologies, Inc \/ Vor Biopharma"},{"orgOrder":0,"company":"Arbor Biotechnologies, Inc","sponsor":"Vertex Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Collaboration","leadProduct":"Ex-vivo Engineered Cell 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    Find Clinical Drug Pipeline Developments & Deals by Arbor Biotechnologies, Inc

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                            01

                            Arbor Biotechnologies, Inc

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                            Arbor Biotechnologies, Inc

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                            Lead Product(s) : ABO-101

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Arbor Biotechnologies Presents ABO-101 Data at ASGCT Annual Meeting

                            Details : ABO-101, a novel gene editing therapeutic, is currently being evaluated in phase 1 clinical trials. It is designed to treat patients suffering from primary hyperoxaluria type 1.

                            Brand Name : ABO-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            May 09, 2024

                            Lead Product(s) : ABO-101

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Arbor Biotechnologies, Inc

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                            Arbor Biotechnologies, Inc

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                            Lead Product(s) : ALLO-329

                            Therapeutic Area : Immunology

                            Study Phase : IND Enabling

                            Sponsor : Allogene Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Allogene and Arbor Announce Agreement for Gene Editing in CAR T Platform

                            Details : Under the agreement, Allogene will use Arbor’s proprietary CRISPR gene-editing technology in its next generation AlloCAR T platform, ALLO-329, for the treatment of autoimmune disease (AID).

                            Brand Name : ALLO-329

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            March 12, 2024

                            Lead Product(s) : ALLO-329

                            Therapeutic Area : Immunology

                            Highest Development Status : IND Enabling

                            Sponsor : Allogene Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            03

                            Arbor Biotechnologies, Inc

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Recipient : 4D Molecular Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            4DMT And Arbor Partner To Co-Develop Next-Gen Genetic Medicines For CNS Diseases

                            Details : 4DMT and Arbor will co-develop and co-commercialize up to six AAV-delivered CRISPR/Cas-based therapeutic candidates for central nervous system diseases, including amyotrophic lateral sclerosis.

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            January 03, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Recipient : 4D Molecular Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            04

                            Arbor Biotechnologies, Inc

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                            Arbor Biotechnologies, Inc

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Endocrinology

                            Study Phase : Discovery

                            Sponsor : Vertex Pharmaceuticals

                            Deal Size : $1,200.0 million

                            Deal Type : Expanded Collaboration

                            DEALS_DEV arrow-down

                            Arbor Biotechnologies Announces Expanded Strategic Partnership with Vertex, Now Extending to Precision Gene Ed...

                            Details : Under the terms of the agreement, Vertex Pharmaceuticals incorporated will receive rights to Arbor’s novel precision editing technology for up to three diseases.

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            January 11, 2023

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Discovery

                            Sponsor : Vertex Pharmaceuticals

                            Deal Size : $1,200.0 million

                            Deal Type : Expanded Collaboration

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                            05

                            Arbor Biotechnologies, Inc

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                            Arbor Biotechnologies, Inc

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                            Lead Product(s) : LNP-based Gene Therapy

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Undisclosed

                            Sponsor : Acuitas

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Arbor Biotechnologies Enters into Agreement with Acuitas Therapeutics for Lipid Nanoparticle Delivery System f...

                            Details : As part of the agreement, the companies will combine the optimized delivery of Acuitas' highly validated LNP technology with Arbor’s differentiated, proprietary CRISPR gene editing technology designed for use in vivo in patients with rare liver disease...

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            August 25, 2022

                            Lead Product(s) : LNP-based Gene Therapy

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Undisclosed

                            Sponsor : Acuitas

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            06

                            Arbor Biotechnologies, Inc

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                            Lead Product(s) : Gavocabtagene autoleucel,Fludarabine Phosphate,Cyclophosphamide

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : TCR2 Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            TCR² Therapeutics and Arbor Biotechnologies Establish Collaboration to Advance Allogeneic TRuC-T Cell Therapi...

                            Details : The collaboration leverages Arbor’s proprietary CRISPR gene-editing technology and TCR 2’s’ TRuC platform, which has demonstrated clinical activity in multiple treatment-refractory mesothelin-expressing solid tumor indications with its lead autolog...

                            Brand Name : Gavo-cel

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            January 04, 2022

                            Lead Product(s) : Gavocabtagene autoleucel,Fludarabine Phosphate,Cyclophosphamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : TCR2 Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            07

                            Arbor Biotechnologies, Inc

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                            Arbor Biotechnologies, Inc

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                            Lead Product(s) : Nuclease Therapies

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Discovery

                            Sponsor : Temasek Life Sciences Laboratory

                            Deal Size : $215.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Arbor Biotechnologies Closes $215 Million Oversubscribed Series B Financing to Advance Next-Generation Precisi...

                            Details : Arbor plans to use the proceeds to advance its lead programs in liver and CNS disease into the clinic and progress a pipeline of precision editing therapeutics, while continuing to invest in its novel discovery engine to develop the next generation of ge...

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            November 09, 2021

                            Lead Product(s) : Nuclease Therapies

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Discovery

                            Sponsor : Temasek Life Sciences Laboratory

                            Deal Size : $215.0 million

                            Deal Type : Series B Financing

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                            08

                            Arbor Biotechnologies, Inc

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                            Arbor Biotechnologies, Inc

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                            Lead Product(s) : Ex-vivo Engineered Cell Therapies

                            Therapeutic Area : Endocrinology

                            Study Phase : Discovery Platform

                            Sponsor : Vertex Pharmaceuticals

                            Deal Size : $1,200.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Vertex and Arbor Biotechnologies Establish New Partnership to Develop Novel Ex Vivo Engineered Cell Therapies

                            Details : Under this new partnership, Vertex will receive rights to use Arbor’s technology to research and develop ex vivo engineered cell therapies towards Vertex’s goal of generating fully differentiated, insulin-producing hypoimmune islet cells for the trea...

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            August 24, 2021

                            Lead Product(s) : Ex-vivo Engineered Cell Therapies

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Discovery Platform

                            Sponsor : Vertex Pharmaceuticals

                            Deal Size : $1,200.0 million

                            Deal Type : Collaboration

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                            09

                            Arbor Biotechnologies, Inc

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                            Arbor Biotechnologies, Inc

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                            Lead Product(s) : Engineered hematopoietic stem cell

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Vor Biopharma

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Vor Biopharma and Arbor Biotechnologies to Collaborate on Engineered Hematopoietic Stem-Cell Therapies

                            Details : The agreement aims to utilize Arbor’s gene editing technologies to engineer hematopoietic stem cells, towards the goal of developing therapies for the treatment of blood cancers, such as acute myeloid leukemia.

                            Brand Name : VOR33

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            September 29, 2020

                            Lead Product(s) : Engineered hematopoietic stem cell

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Vor Biopharma

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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