Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Triamcinolone Acetonide
Therapeutic Area : Ophthalmology
Study Phase : Approved
Sponsor : Clearside Biomedical
Deal Size : Undisclosed
Deal Type : Collaboration
Clearside & Arctic Vision Partner with Santen for ARVN001 in Uveitic Macular Edema
Details : Under the agreement, Arctic Vision has granted the rights of Arcatus (triamcinolone acetonide injectable suspension) to Santen to commercialize in China for macular edema associated with uveitis.
Brand Name : Arcatus
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 07, 2024
Lead Product(s) : Triamcinolone Acetonide
Therapeutic Area : Ophthalmology
Highest Development Status : Approved
Sponsor : Clearside Biomedical
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Triamcinolone Acetonide
Therapeutic Area : Ophthalmology
Study Phase : Approved
Sponsor : Clearside Biomedical
Deal Size : Not Applicable
Deal Type : Not Applicable
Clearside Biomedical’s Partner Reports Positive Phase 3 Results for ARCATUS® in China
Details : Arcatus is a proprietary suspension of the corticosteroid triamcinolone acetonide for administration to the suprachoroidal space for the treatment of macular edema associated with uveitis.
Brand Name : Arcatus
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 29, 2024
Lead Product(s) : Triamcinolone Acetonide
Therapeutic Area : Ophthalmology
Highest Development Status : Approved
Sponsor : Clearside Biomedical
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Triamcinolone Acetonide
Therapeutic Area : Ophthalmology
Study Phase : Approved
Sponsor : Clearside Biomedical
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Arcatus is a proprietary suspension of the corticosteroid triamcinolone acetonide for administration to the suprachoroidal space for the treatment of macular edema associated with uveitis and is referred as Xipere, approved in United States.
Brand Name : Arcatus
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 10, 2023
Lead Product(s) : Triamcinolone Acetonide
Therapeutic Area : Ophthalmology
Highest Development Status : Approved
Sponsor : Clearside Biomedical
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Pilocarpine Hydrochloride
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Eyenovia
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ARVN003 (pilocarpine microdose ophthalmic solution/Microline), a proprietary formulation based on microdosing platform Optejet® for the pharmacologic treatment for presbyopia.
Brand Name : MicroLine
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 06, 2022
Lead Product(s) : Pilocarpine Hydrochloride
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Eyenovia
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Triamcinolone Acetonide
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Recipient : Clearside Biomedical
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : XIPERE, referred to as ARVN001 by Arctic Vision, is a proprietary suspension of the corticosteroid triamcinolone acetonide formulated for administration to the suprachoroidal space (SCS®) using Clearside’s patented SCS Microinjector®.
Brand Name : Xipere
Molecule Type : Small molecule
Upfront Cash : $3.0 million
September 09, 2021
Lead Product(s) : Triamcinolone Acetonide
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Recipient : Clearside Biomedical
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Pilocarpine Hydrochloride
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Eyenovia
Deal Size : Not Applicable
Deal Type : Not Applicable
China NMPA Clears Arctic Vision’s IND Application for Phase III study of ARVN003 to Treat Presbyopia
Details : ARVN003 is a pharmacologic treatment for presbyopia. The product is developed based on Optejet, a proprietary micro-dosing administration device utilizing MAP technology, and pilocapine, the well-established ophthalmic medicine for temporary improvement ...
Brand Name : MicroLine
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 03, 2021
Lead Product(s) : Pilocarpine Hydrochloride
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Eyenovia
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Triamcinolone Acetonide
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Clearside Biomedical
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : ARVN001 is a proprietary suspension of the corticosteroid triamcinolone acetonide formulated for administration to the suprachoroidal space (SCS®) through Clearside’s patented SCS Microinjector®.
Brand Name : Xipere
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 15, 2021
Lead Product(s) : Triamcinolone Acetonide
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Clearside Biomedical
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : ARVN601
Therapeutic Area : Ophthalmology
Study Phase : Preclinical
Sponsor : University of Hong Kong
Deal Size : Undisclosed
Deal Type : Collaboration
Details : ARVN601 Neuroprotection, in the form of non-IOP-related interventions to prevent or delay glaucomatous neurodegeneration, has been underscored to be an unmet need in the management of glaucoma ever since the 2010 World Glaucoma Association Consensus Meet...
Brand Name : ARVN601
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
July 05, 2021
Lead Product(s) : ARVN601
Therapeutic Area : Ophthalmology
Highest Development Status : Preclinical
Sponsor : University of Hong Kong
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Rho-associated kinase-Human corneal endothelial cells
Therapeutic Area : Ophthalmology
Study Phase : Preclinical
Recipient : ActualEyes
Deal Size : $35.0 million
Deal Type : Licensing Agreement
Details : Arctic Vision will develop and market ActualEyes’ AE-101, for the treatment of corneal endothelial dysfunction in Greater China and South Korea. ARVN901 (AE-101) is a novel cell-injection therapy developed using cultured hCECs combined with a ROCK inhi...
Brand Name : AE101
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
May 14, 2021
Lead Product(s) : Rho-associated kinase-Human corneal endothelial cells
Therapeutic Area : Ophthalmology
Highest Development Status : Preclinical
Recipient : ActualEyes
Deal Size : $35.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Triamcinolone Acetonide
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Loyal Valley Capital
Deal Size : $100.0 million
Deal Type : Series B Financing
Details : Arctic Vision currently has three late-stage in-licensed products: ARVN001 for uveitic macular edema (UME), ARVN002 for pediatric progressive myopia and ARVN003 for presbyopia.
Brand Name : ARVN001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 10, 2021
Lead Product(s) : Triamcinolone Acetonide
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Loyal Valley Capital
Deal Size : $100.0 million
Deal Type : Series B Financing
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