Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Insulin aspart
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
At278 Insulin Shows Superiority in Phase I Trial for Type 2 Diabetes
Details : AT278 is an ultra-concentrated, ultra-rapid acting, novel formulation of insulin that accelerates the absorption of insulin post injection. It is being evaluated for the treatment of type 2 diabetics.
Brand Name : AT278
Molecule Type : Peptide
Upfront Cash : Not Applicable
May 20, 2024
Lead Product(s) : Insulin aspart
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Insulin
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Sponsor : Medtronic Plc
Deal Size : Undisclosed
Deal Type : Collaboration
Arecor and Medtronic Collaborate to Develop Novel Thermostable Insulin for Pump Delivery
Details : The collaboration aims to develop a novel, high concentration, thermostable insulin for use by Medtronic’s Diabetes business in a next-generation implantable pump.
Brand Name : Undisclosed
Molecule Type : Peptide
Upfront Cash : Undisclosed
May 09, 2024
Lead Product(s) : Insulin
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Sponsor : Medtronic Plc
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Semaglutide
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Sponsor : TRx BIOSCIENCES
Deal Size : Undisclosed
Deal Type : Collaboration
Arecor and TRX Biosciences Establish Collaboration for Oral GLP-1 Development
Details : A collaboration will enhance oral semaglutide's bioavailability using novel lipid technology for diabetes and obesity treatment.
Brand Name : Undisclosed
Molecule Type : Peptide
Upfront Cash : Undisclosed
March 12, 2024
Lead Product(s) : Semaglutide
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Sponsor : TRx BIOSCIENCES
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Glucagon
Therapeutic Area : Endocrinology
Study Phase : Approved
Recipient : Tetris Pharma
Deal Size : Undisclosed
Deal Type : Agreement
Tetris Pharma Signs Service Agreement With Syneos Health
Details : Ogluo® is a ready-to-use, ambiently stored, preparation of glucagon that has been specifically designed for patients living with diabetes with severe hypoglycaemia.
Brand Name : Ogluo
Molecule Type : Peptide
Upfront Cash : Undisclosed
December 12, 2022
Lead Product(s) : Glucagon
Therapeutic Area : Endocrinology
Highest Development Status : Approved
Recipient : Tetris Pharma
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Ultra Rapid Acting Prandial Insulin Aspart
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AT247 (ultra rapid acting prandial insulin aspart) has the potential to significantly improve blood glucose control when delivered via insulin pump and is an important step in enabling the development of a fully closed loop/artificial pancreas system for...
Brand Name : AT247
Molecule Type : Peptide
Upfront Cash : Not Applicable
October 11, 2022
Lead Product(s) : Ultra Rapid Acting Prandial Insulin Aspart
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Adalimumab
Therapeutic Area : Immunology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Humira approved as 50 mg/mL adalimumab product comprising citrate as formulation ingredient. An product was subsequently launched by AbbVie with high adalimumab concentration in absence of citrate, providing greater patient convenience due to the lower i...
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 09, 2022
Lead Product(s) : Adalimumab
Therapeutic Area : Immunology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Glucagon
Therapeutic Area : Endocrinology
Study Phase : Approved
Recipient : Tetris Pharma
Deal Size : Undisclosed
Deal Type : Acquisition
Xeris’ Commercialization Partner for Ogluo, Tetris Pharma Ltd, to Be Acquired by Arecor Therapeutics
Details : Under the terms of the proposed acquisition, Arecor Therapeutics has agreed to acquire Tetris Pharma and will continue to commercialize Ogluo in the UK and EEA. Gvoke® (US) /Ogluo® (EU), the first prescription, ready-to-use, pre-mixed, pre-measured glu...
Brand Name : Ogluo
Molecule Type : Peptide
Upfront Cash : Undisclosed
August 01, 2022
Lead Product(s) : Glucagon
Therapeutic Area : Endocrinology
Highest Development Status : Approved
Recipient : Tetris Pharma
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : Ultra-Concentrated Rapid Acting Insulin Aspart
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Data from Phase I clinical trial of AT278 (Ultra-Concentrated Rapid Acting Insulin Aspart), showed that it exhibited an accelerated PK and PD profile when compared to NovoRapid®, a gold standard prandial insulin treatment, despite a 5-fold increase in c...
Brand Name : AT278
Molecule Type : Peptide
Upfront Cash : Not Applicable
May 18, 2022
Lead Product(s) : Ultra-Concentrated Rapid Acting Insulin Aspart
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ultra-Concentrated Rapid Acting Insulin Aspart
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PK/PD profile for AT278 was accelerated compared with NovoRapid. Following dosing, AT278 showed faster onset of insulin exposure compared with NovoRapid, demonstrated by an earlier onset of appearance, also showed rapid onset of glucose-lowering effect c...
Brand Name : AT278
Molecule Type : Peptide
Upfront Cash : Not Applicable
April 28, 2022
Lead Product(s) : Ultra-Concentrated Rapid Acting Insulin Aspart
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ultra-Concentrated Rapid Acting Insulin Aspart
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AT278, is an ultra-concentrated novel formulation of insulin, that has been designed to significantly accelerate insulin absorption post injection to enable more effective and convenient management of blood glucose levels in people with high daily insuli...
Brand Name : AT278
Molecule Type : Peptide
Upfront Cash : Not Applicable
April 12, 2022
Lead Product(s) : Ultra-Concentrated Rapid Acting Insulin Aspart
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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