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argenx","highestDevelopmentStatusID":"12","companyTruncated":"Argenx \/ argenx"},{"orgOrder":0,"company":"Argenx","sponsor":"Zai Lab","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"NETHERLANDS","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Efgartigimod Alfa","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Argenx","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Argenx \/ Zai Lab","highestDevelopmentStatusID":"12","companyTruncated":"Argenx \/ Zai Lab"},{"orgOrder":0,"company":"Argenx","sponsor":"OncoVerity","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Series A Financing","leadProduct":"Cusatuzumab","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Argenx","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Argenx \/ Argenx","highestDevelopmentStatusID":"12","companyTruncated":"Argenx \/ Argenx"},{"orgOrder":0,"company":"Argenx","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Efgartigimod Alfa","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Argenx","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Argenx \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Argenx \/ Not Applicable"}]

Find Clinical Drug Pipeline Developments & Deals by Argenx

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The proceeds will fund Phase 2 of OV-1001 (cusatuzumab), a novel, first-in-class high-affinity monoclonal anti-CD70 antibody, in combination with venetoclax and azacitidine for newly diagnosed AML.

                          Brand Name : OV-1001

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          November 21, 2024

                          Lead Product(s) : Cusatuzumab,Azacitidine,Venetoclax

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Recipient : OncoVerity

                          Deal Size : Undisclosed

                          Deal Type : Series A Financing

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                          02

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Vyvgart Hytrulo, a subcutaneous combination of efgartigimod alfa, a human IgG1 antibody fragment, and recombinant human hyaluronidase PH20, It is being developed for CIDP.

                          Brand Name : Vyvgart Hytrulo

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 20, 2024

                          Lead Product(s) : Efgartigimod Alfa,Hyaluronidase

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Vyvgart Hytrulo, a subcutaneous combination of efgartigimod alfa, a human IgG1 antibody fragment and recombinant human hyaluronidase PH20, it is indicated for CIPD.

                          Brand Name : Vyvgart Hytrulo

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 11, 2024

                          Lead Product(s) : Efgartigimod Alfa,Hyaluronidase

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Zai Lab

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Argenx gains access to Halozyme's ENHANZE, a proprietary rHuPH20 enzyme for subcutaneous drug delivery, for six targets, including FcRn target, Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase).

                          Brand Name : Vyvgart Hytrulo

                          Molecule Type : Large molecule

                          Upfront Cash : $30.0 million

                          October 03, 2024

                          Lead Product(s) : Efgartigimod Alfa,Hyaluronidase

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved

                          Recipient : Halozyme Therapeutics

                          Deal Size : $370.0 million

                          Deal Type : Collaboration

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                          05

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Vyvgart is a subcutaneous formulation of efgartigimod alfa, a human IgG1 antibody fragment, approved for the treatment of Generalized Myasthenia Gravis.

                          Brand Name : Vyvgart

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          July 16, 2024

                          Lead Product(s) : Efgartigimod

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved

                          Recipient : Zai Lab

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Vyvgart Hytrulo, a subcutaneous combination of efgartigimod alfa, a human IgG1 antibody fragment, and recombinant human hyaluronidase PH20, It is being developed for CIDP.

                          Brand Name : Vyvgart Hytrulo

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 21, 2024

                          Lead Product(s) : Efgartigimod Alfa,Hyaluronidase

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Vyvgart (efgartigimod alfa) is a USFDA approved neonatal Fc receptor blocker, which is being evaluated for the treatment of adult patients with primary sjogren’s disease.

                          Brand Name : Vyvgart

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 27, 2024

                          Lead Product(s) : Efgartigimod Alfa

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : VYVGART (efgartigimod alfa) is a USFDA approved neonatal Fc receptor blocker, which is approved for the treatment of adult patients with primary immune thrombocytopenia.

                          Brand Name : Vyvgart

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 26, 2024

                          Lead Product(s) : Efgartigimod Alfa

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Vyvgart Hytrulo, a combination of efgartigimod alfa, a human IgG1 antibody fragment, & recombinant human hyaluronidase PH20, evaluated for treating chronic inflammatory demyelinating polyneuropathy.

                          Brand Name : Vyvgart Hytrulo

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          February 20, 2024

                          Lead Product(s) : Efgartigimod,rHuPH20

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Vyvdura (efgartigimod alfa and hyaluronidase-qvfc) is a human IgG1 antibody fragment marketed for intravenous use. It is approved for the treatment of Generalized myasthenia gravis (gMG).

                          Brand Name : Vyvdura

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          January 18, 2024

                          Lead Product(s) : Efgartigimod Alfa,Hyaluronidase-qvfc

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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