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    [{"orgOrder":0,"company":"Aridis Pharmaceuticals","sponsor":"Cystic Fibrosis Foundation","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Funding","leadProduct":"Gallium Citrate","moa":"Bacterial growth","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Aridis Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Nasal Aerosol","sponsorNew":"Aridis Pharmaceuticals \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"8","companyTruncated":"Aridis Pharmaceuticals \/ Cystic Fibrosis Foundation"},{"orgOrder":0,"company":"Aridis Pharmaceuticals","sponsor":"AstraZeneca","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Antibody","year":"2023","type":"Termination","leadProduct":"Suvratoxumab","moa":"Staphylococcus aureus alpha toxin 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Diseases","graph2":"Phase III","graph3":"Aridis Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Aridis Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Aridis Pharmaceuticals \/ Inapplicable"}]

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                            01

                            Aridis Pharmaceuticals

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                            Lead Product(s) : Tosatoxumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aridis AR-301 Monoclonal Antibody is Among the First Biologics to Receive FDAs Qualified Infectious Diseases P...

                            Details : AR-301 (tosatoxumab), a fully human IgG1 monoclonal antibody that specifically targets S. aureus alpha-toxin, an important virulence factor that is secreted by both methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus, is being de...

                            Product Name : Salvecin

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            December 07, 2023

                            Lead Product(s) : Tosatoxumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Aridis Pharmaceuticals

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                            Aridis Pharmaceuticals

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                            Lead Product(s) : Tosatoxumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aridis Receives Agreement from the European Medicines Agency (EMA) on the Clinical Study Design and a Single C...

                            Details : AR-301 (tosatoxumab) is a fully human IgG1 monoclonal antibody that specifically targets S. aureus alpha-toxin, an important virulence factor that is secreted by both methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus being deve...

                            Product Name : Salvecin

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            July 17, 2023

                            Lead Product(s) : Tosatoxumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

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                            Lead Product(s) : Tosatoxumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aridis Pharmaceuticals' AR-301 Eligible for Consideration Under FDA's Limited Population Pathway for Antibacte...

                            Details : AR-301 (tosatoxumab) is a fully human IgG1 monoclonal antibody that specifically targets S. aureus alpha-toxin, an important virulence factor that is secreted by both methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus being deve...

                            Product Name : Salvecin

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            June 20, 2023

                            Lead Product(s) : Tosatoxumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Aridis Pharmaceuticals

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                            Lead Product(s) : Tosatoxumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aridis Receives Agreement from the FDA on a Single Confirmatory Phase 3 Study of AR-301 and the Clinical Study...

                            Details : AR-301 (tosatoxumab) is a fully human IgG1 monoclonal antibody that specifically targets S. aureus alpha-toxin, an important virulence factor that is secreted by both methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus being deve...

                            Product Name : Salvecin

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            May 31, 2023

                            Lead Product(s) : Tosatoxumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Aridis Pharmaceuticals

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                            Aridis Pharmaceuticals

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                            Lead Product(s) : Suvratoxumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : AstraZeneca

                            Deal Size : $126.0 million

                            Deal Type : Termination

                            DEALS_DEV arrow-down

                            AstraZeneca Pulls Pneumonia Collab With Aridis Over Allegations Of A Missed Payment

                            Details : AstraZeneca terminated the collaboration with Aridis for the licensing of the AR-320 (suvratoxumab), a fully human, half-life extended IgG1 monoclonal antibody targeting S. aureus alpha toxin.

                            Product Name : AR-320

                            Product Type : Antibody

                            Upfront Cash : $11.0 million

                            March 31, 2023

                            Lead Product(s) : Suvratoxumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : AstraZeneca

                            Deal Size : $126.0 million

                            Deal Type : Termination

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                            06

                            Aridis Pharmaceuticals

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                            Lead Product(s) : Gallium Citrate

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aridis Meets Primary and Secondary Endpoints in Phase 2a Study of AR-501 in Cystic Fibrosis Patients

                            Details : AR-501 is a novel inhaled formulation of gallium citrate with broad-spectrum anti-infective activity involving iron acquisition and metabolism, is being developed to treat chronic lung infections in cystic fibrosis (CF) patients.

                            Product Name : AR-501

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 13, 2023

                            Lead Product(s) : Gallium Citrate

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Aridis Pharmaceuticals

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                            Aridis Pharmaceuticals

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                            Lead Product(s) : Tosatoxumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Aridis Reports Top-Line Results of the Phase 3 Double-Blinded, Superiority Trial of AR-301 For the Treatment o...

                            Details : AR-301 is a fully human IgG1 monoclonal antibody that targets S. aureus alpha-toxin (virulence factor that is secreted by both MRSA and MSSA). It is designed to protect against alpha-toxin mediated destruction of host cells, preserving a functional host ...

                            Product Name : Salvecin

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            January 25, 2023

                            Lead Product(s) : Tosatoxumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Aridis Pharmaceuticals

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                            Lead Product(s) : Gallium Citrate

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            New Approaches to Treating Infections in Cystic Fibrosis Patients - AR 501 Phase 2 Trial Update

                            Details : AR-501 is a novel inhaled formulation of gallium citrate with broad-spectrum anti-infective activity involving iron acquisition and metabolism, is being developed to treat chronic lung infections in cystic fibrosis (CF) patients.

                            Product Name : AR-501

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 17, 2023

                            Lead Product(s) : Gallium Citrate

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Aridis Pharmaceuticals

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                            Lead Product(s) : Gallium Citrate

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Cystic Fibrosis Foundation

                            Deal Size : $12.5 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            CF Foundation Invests Up to $4.85 Million in Aridis Pharmaceuticals for Testing of Anti-Infective

                            Details : AR-501 is a novel, small molecule and an inhalable form of gallium citrate, which acts as an iron analog to starve bacteria of iron. Gallium is believed to inhibit multiple iron-dependent synthetic and metabolic pathways required for pathogenicity.

                            Product Name : AR-501

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            December 12, 2022

                            Lead Product(s) : Gallium Citrate

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Cystic Fibrosis Foundation

                            Deal Size : $12.5 million

                            Deal Type : Funding

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                            10

                            Aridis Pharmaceuticals

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                            Lead Product(s) : Gallium Citrate

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Aridis Announces a Key Milestone of Closing of Patient Enrollment in the Phase 2a Study of AR-501 in Cystic Fi...

                            Details : AR-501 (gallium citrate) is an inhalable broad-spectrum anti-infective currently under development for controlling debilitating chronic lung infections in cystic fibrosis (CF) patients.

                            Product Name : AR-501

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 30, 2022

                            Lead Product(s) : Gallium Citrate

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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