Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : AX-158
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Eli Lilly
Deal Size : $8.0 million
Deal Type : Financing
Artax Biopharma Raises $8 Million Ahead of Phase 2a Data Expected in Q4-2024
Details : The financing aims to fund the Artax's lead asset, AX-158, is the first in a new class of Nck blockers, which is being evaluated in the mid-stage clinical trial studies for the treatment of psoriasis.
Brand Name : AX-158
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 06, 2024
Lead Product(s) : AX-158
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Eli Lilly
Deal Size : $8.0 million
Deal Type : Financing
Lead Product(s) : AX-158
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Artax Announces First Patient Dosed in Phase 2a Psoriasis Trial Evaluating AX-158
Details : AX-158 is a first in class oral Nck blocker, which is being evaluated in phase 2 clinical trials for the treatment of mild to moderate plaque psoriasis.
Brand Name : AX-158
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 13, 2024
Lead Product(s) : AX-158
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : AX-158
Therapeutic Area : Dermatology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Artax Granted Clinical Trial Authorization for AX-158 Phase 2a Psoriasis Study
Details : AX-158 is a first-in-class, oral small molecule for the treatment of autoimmune diseases and selectively modulates, or adjusts, T Cell responses that play a critical role in immune system function. By selectively inhibiting Nck, a protein.
Brand Name : AX-158
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 09, 2023
Lead Product(s) : AX-158
Therapeutic Area : Dermatology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : AX-158
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AX-158 is a first-in-class, oral small molecule for the treatment of autoimmune diseases and selectively modulates, or adjusts, T Cell responses that play a critical role in immune system function. By selectively inhibiting Nck, a protein.
Brand Name : AX-158
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 01, 2023
Lead Product(s) : AX-158
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : AX-158
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Eli Lilly
Deal Size : $26.0 million
Deal Type : Financing
Details : Artax will use these funds to support the clinical development of AX-158 in autoimmune diseases, including the addition of key clinical development personnel. AX-158 has the potential to treat T Cell-mediated diseases without the risk of immunosuppressio...
Brand Name : AX-158
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 11, 2022
Lead Product(s) : AX-158
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Eli Lilly
Deal Size : $26.0 million
Deal Type : Financing
Lead Product(s) : AX-158
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Artax Biopharma Granted MHRA Clinical Trial Authorization for AX-158
Details : In preclinical studies, AX-158 decreased key cytokines including INFγ, TNFα and IL-2. Based on this activity, Artax is planning future clinical development in autoimmune diseases, T cell malignancies and other related T cell pathologies.
Brand Name : AX-158
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 13, 2021
Lead Product(s) : AX-158
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : AX-158
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : U.S. Patent covers AX-158, certain additional backup compounds, and pharmaceutical compositions thereof, and is expected to expire no earlier than 2039 in the United States.
Brand Name : AX-158
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 17, 2020
Lead Product(s) : AX-158
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : AX-158
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Artax Biopharma is poised to enter clinical trials with the small molecule AX- 158, a novel approach to treat multiple autoimmune diseases without causing the immunosuppression commonly associated with current autoimmune disease therapies.
Brand Name : AX-158
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 24, 2020
Lead Product(s) : AX-158
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : AX-158
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : Columbus Venture Partners
Deal Size : Undisclosed
Deal Type : Series B Financing
Details : Proceeds from the financing will be used to support activities for a planned Q4 2020 filing of a Clinical Trial Application (CTA) with the United Kingdom’s Medicines and Healthcare Products Regulatory Agency (MHRA) for AX-158.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 04, 2020
Lead Product(s) : AX-158
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : Columbus Venture Partners
Deal Size : Undisclosed
Deal Type : Series B Financing
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