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    [{"orgOrder":0,"company":"Artiva Biotherapeutics","sponsor":"5AM Ventures","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Series A Financing","leadProduct":"AB-101","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Artiva Biotherapeutics","amount2":0.080000000000000002,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0.080000000000000002,"dosageForm":"","sponsorNew":"Artiva Biotherapeutics \/ 5AM Ventures","highestDevelopmentStatusID":"7","companyTruncated":"Artiva Biotherapeutics \/ 5AM Ventures"},{"orgOrder":0,"company":"Artiva Biotherapeutics","sponsor":"Merck & Co","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Collaboration","leadProduct":"AB-MK-001","moa":"","graph1":"Oncology","graph2":"Discovery Platform","graph3":"Artiva 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Capital"},{"orgOrder":0,"company":"Artiva Biotherapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Not Applicable","leadProduct":"CAR-NK Cell Therapy","moa":"CD16","graph1":"Oncology","graph2":"IND Enabling","graph3":"Artiva Biotherapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Artiva Biotherapeutics \/ Not Applicable","highestDevelopmentStatusID":"5","companyTruncated":"Artiva Biotherapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Artiva Biotherapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Not Applicable","leadProduct":"AB-101","moa":"ADCC","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Artiva Biotherapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Artiva Biotherapeutics \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Artiva Biotherapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Artiva Biotherapeutics","sponsor":"Affimed","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Large molecule","year":"2022","type":"Partnership","leadProduct":"AB-101","moa":"CD30","graph1":"Oncology","graph2":"Phase II","graph3":"Artiva Biotherapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Artiva Biotherapeutics \/ Artiva Biotherapeutics","highestDevelopmentStatusID":"8","companyTruncated":"Artiva Biotherapeutics \/ Artiva Biotherapeutics"},{"orgOrder":0,"company":"Artiva Biotherapeutics","sponsor":"Affimed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"GERMANY","productType":"Large molecule","year":"2023","type":"Not Applicable","leadProduct":"AB-101","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"Artiva Biotherapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Artiva Biotherapeutics \/ Artiva Biotherapeutics","highestDevelopmentStatusID":"8","companyTruncated":"Artiva Biotherapeutics \/ Artiva Biotherapeutics"},{"orgOrder":0,"company":"Artiva Biotherapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Not Applicable","leadProduct":"AB-101","moa":"","graph1":"Immunology","graph2":"IND Enabling","graph3":"Artiva Biotherapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"","sponsorNew":"Artiva Biotherapeutics \/ Not Applicable","highestDevelopmentStatusID":"5","companyTruncated":"Artiva Biotherapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Artiva Biotherapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Not Applicable","leadProduct":"AB-101","moa":"","graph1":"Nephrology","graph2":"Phase I","graph3":"Artiva Biotherapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Artiva Biotherapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Artiva Biotherapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Artiva Biotherapeutics","sponsor":"Jefferies","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Public Offering","leadProduct":"AB-101","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"Artiva Biotherapeutics","amount2":0.17000000000000001,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0.17000000000000001,"dosageForm":"","sponsorNew":"Artiva Biotherapeutics \/ Jefferies","highestDevelopmentStatusID":"8","companyTruncated":"Artiva Biotherapeutics \/ Jefferies"}]

    Find Clinical Drug Pipeline Developments & Deals by Artiva Biotherapeutics

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                            01

                            Artiva Biotherapeutics

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                            Lead Product(s) : AB-101,Acimtamig,Cyclophosphamide

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Jefferies

                            Deal Size : $167.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Artiva upsizes IPO to $167 million as NK cell therapy biotech heads to Nasdaq

                            Details : The net proceeds will be used to fund the clinical development of the company's lead product AlloNK (AB-101), which is being evaluated for the treatment of r/r Hodgkin Lymphoma.

                            Brand Name : AlloNK

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            July 18, 2024

                            Lead Product(s) : AB-101,Acimtamig,Cyclophosphamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Jefferies

                            Deal Size : $167.0 million

                            Deal Type : Public Offering

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                            02

                            Artiva Biotherapeutics

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                            Lead Product(s) : AB-101,Rituximab,Cyclophosphamide

                            Therapeutic Area : Nephrology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Artiva Biotherapeutics Receives FDA Fast Track Designation for AlloNK® in Lupus Nephritis

                            Details : AlloNK (AB-101) is an allogeneic NK cell therapy designed to enhance antibody-dependent cellular cytotoxicity in combination with rituximab or obinutuzumab for treating lupus nephritis.

                            Brand Name : AlloNK

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            February 22, 2024

                            Lead Product(s) : AB-101,Rituximab,Cyclophosphamide

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

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                            Lead Product(s) : AB-101,Rituximab

                            Therapeutic Area : Immunology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Artiva Biotherapeutics Announces FDA Clearance of IND for AlloNK® Cell Therapy Candidate in Combination with ...

                            Details : AlloNK (AB-101) is a non-genetically modified, cord blood-derived, allogeneic, cryopreserved, ADCC-enhancing NK cell therapy candidate for use in combination with Combination with Rituximab in Lupus Nephritis.

                            Brand Name : AlloNK

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            August 16, 2023

                            Lead Product(s) : AB-101,Rituximab

                            Therapeutic Area : Immunology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Artiva Biotherapeutics

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                            Lead Product(s) : AFM13,AB-101

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Recipient : Affimed

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Affimed Announces IND Clearance for a Phase 2 Clinical Trial Investigating AFM13 and AB-101 Combination Therap...

                            Details : AFM13 is a first-in-class innate cell engager (ICE®) that uniquely leverags the power of the innate immune system by engaging and activating natural killer (NK) cells and macrophages to destroy CD30-positive hematologic tumors.

                            Brand Name : AFM13

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            May 23, 2023

                            Lead Product(s) : AFM13,AB-101

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Recipient : Affimed

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Artiva Biotherapeutics

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                            Lead Product(s) : AFM13,AB-101

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : Affimed

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Affimed and Artiva Biotherapeutics Announce Partnership to Advance Combination Therapy of Innate Cell Engager ...

                            Details : Under the terms of the agreement, Affimed and Artiva will pursue the development of the AFM13/AB-101 combination treatment in the United States on a co-exclusive basis. Affimed will lead regulatory activities through Phase 2 and any confirmatory studies.

                            Brand Name : AFM13

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            November 03, 2022

                            Lead Product(s) : AFM13,AB-101

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : Affimed

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            Lead Product(s) : AB-101,Rituximab,Interleukin 2

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Artiva Announces AB-101 Abstract Accepted for Presentation at Society for Immunotherapy of Cancer (SITC) 2022 ...

                            Details : AB-101, an ADCC enhancer NK-cell therapy candidate for use in combination with monoclonal antibodies or innate-cell engagers. Artiva is currently advancing a Phase 1/2 of AB-101 in combination with rituximab for the treatment of relapsed or refractory B-...

                            Brand Name : AB-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            October 05, 2022

                            Lead Product(s) : AB-101,Rituximab,Interleukin 2

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : CAR-NK Cell Therapy

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Artiva Biotherapeutics Announces FDA Allowance of IND for AB-201, a HER2-Targeted CAR-NK for the Treatment of ...

                            Details : AB-201 is an allogeneic HER2-targeted CAR-NK cell therapy for the treatment of solid tumors in the outpatient setting with the option for repeat dosing. AB-201 has demonstrated potent anti-tumor activity in multiple preclinical HER2-positive tumor model ...

                            Brand Name : AB-201

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            September 20, 2022

                            Lead Product(s) : CAR-NK Cell Therapy

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : AB-101,Rituximab,Interleukin 2

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Venrock Healthcare Capital

                            Deal Size : $120.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Artiva Raises $120M in Series B Financing to Advance Pipeline of Allogeneic NK Cell Therapies

                            Details : Artiva’s pipeline includes AB-101, an ADCC enhancer NK-cell therapy which is currently under Phase 1/2 clinical trial in combination with rituximab for the treatment of relapsed or refractory B-cell lymphomas.

                            Brand Name : AB-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            February 26, 2021

                            Lead Product(s) : AB-101,Rituximab,Interleukin 2

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Venrock Healthcare Capital

                            Deal Size : $120.0 million

                            Deal Type : Series B Financing

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                            Lead Product(s) : AB-MK-001

                            Therapeutic Area : Oncology

                            Study Phase : Discovery Platform

                            Sponsor : Merck & Co

                            Deal Size : $1,866.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Artiva Biotherapeutics Announces Exclusive Worldwide Collaboration with Merck to Develop Candidate CAR-NK Cell...

                            Details : The collaboration initially includes two CAR-NK programs (AB-MK-001 and AB-MK-002) with an option for a third, none of which are in Artiva’s current or planned pipeline.

                            Brand Name : AB-MK-001

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : $30.0 million

                            January 28, 2021

                            Lead Product(s) : AB-MK-001

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery Platform

                            Sponsor : Merck & Co

                            Deal Size : $1,866.0 million

                            Deal Type : Collaboration

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                            Lead Product(s) : AB-101,Anti-CD20 monoclonal antibody

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : 5AM Ventures

                            Deal Size : $78.0 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            Artiva Biotherapeutics Launches with $78 Million Series A Financing to Advance NK Cell Therapies

                            Details : The company plans to enter the clinic this year with AB-101 in combination with an anti-CD20 monoclonal antibody for the treatment of relapsed refractory B-cell lymphoma.

                            Brand Name : AB-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            June 26, 2020

                            Lead Product(s) : AB-101,Anti-CD20 monoclonal antibody

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : 5AM Ventures

                            Deal Size : $78.0 million

                            Deal Type : Series A Financing

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