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    [{"orgOrder":0,"company":"GSK","sponsor":"Xiamen Innovax Biotech","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Small molecule","year":"2020","type":"Agreement","leadProduct":"AS03","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Undisclosed","graph3":"GSK","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"","sponsorNew":"GSK \/ Xiamen Innovax Biotech ","highestDevelopmentStatusID":"1","companyTruncated":"GSK \/ Xiamen Innovax Biotech "},{"orgOrder":0,"company":"Medicago","sponsor":"GSK","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Vaccine","year":"2020","type":"Not Applicable","leadProduct":"AS03","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Medicago","amount2":0,"highestDevelopmentShortName":"Ph 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Infectious Diseases","country":"","productType":"Vaccine","year":"2021","type":"Not Applicable","leadProduct":"AS03","moa":"SARS-CoV-2 spike protein","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Medicago","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Medicago \/ Glaxosmith Kline","highestDevelopmentStatusID":"10","companyTruncated":"Medicago \/ Glaxosmith Kline"},{"orgOrder":0,"company":"Sanofi","sponsor":"GSK","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Vaccine","year":"2022","type":"Not Applicable","leadProduct":"AS03","moa":"SARS-CoV-2 spike protein","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Sanofi","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"Sanofi \/ GSK","highestDevelopmentStatusID":"10","companyTruncated":"Sanofi \/ GSK"},{"orgOrder":0,"company":"SK Chemicals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Vaccine","year":"2023","type":"Not Applicable","leadProduct":"AS03","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"SK Chemicals","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"SK Chemicals \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"SK Chemicals \/ Not Applicable"}]

    Find Clinical Drug Pipeline Developments & Deals for AS03

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    AS03

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                            01

                            Sanofi

                            France
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                            Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

                            Lead Product(s) : SARS-CoV-2 Recombinant Protein Vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Sanofi and GSK to Seek Regulatory Authorization for Covid19 Vaccine

                            Details : Data from Phase 3 VAT08 and VAT02 efficacy study showed that two doses of Sanofi-GSK booster vaccine SP0253 or GSK4353001A (SARS-CoV-2 recombinant protein vaccine) generated an efficacy of 100%, 75%, 57.9% against severe COVID-19 disease.

                            Brand Name : SP0253

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            February 23, 2022

                            Lead Product(s) : SARS-CoV-2 Recombinant Protein Vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            SK Chemicals

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                            SK Chemicals

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                            Lead Product(s) : Recombinant Adjuvanted Covid-19 Vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Regulatory Approval of COVID-19 Vaccine SKYCovion

                            Details : SKYCovion contains nanoparticles of recombinant Receptor Binding Domain (RBD) of SARS-CoV-2 Spike (S) protein from the parental D614G strain and an adjuvant system (AS03) and got approval by MHRA for treating COVID-19 infection.

                            Brand Name : SKYCovion

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            May 26, 2023

                            Lead Product(s) : Recombinant Adjuvanted Covid-19 Vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Medicago

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                            Fi Europe 2024
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                            Medicago

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                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Medicago Submits Phase 3 Data to Health Canada for Its Plant-Based COVID-19 Vaccine Candidate

                            Details : Apart from Canada regulatory filing has also been initiated for USFDA and MHRA for CoVLP (Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine), the first-ever plant-based vaccine, final portion of data submitted as part of New Drug Submission CO...

                            Brand Name : CoVLP

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            December 16, 2021

                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Medicago

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                            Fi Europe 2024
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                            Medicago

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                            Lead Product(s) : CoVLP Adjuvanted Vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Medicago and GSK Announce Positive Phase 3 Efficacy and Safety Results for Adjuvanted Plant-Based COVID-19 Vac...

                            Details : Covid19 Vaccine candidate demonstrated efficacy against all variants seen in the study, including 75.3% efficacy against COVID-19 of any severity caused by the globally dominant Delta variant.

                            Brand Name : Undisclosed

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            December 07, 2021

                            Lead Product(s) : CoVLP Adjuvanted Vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Medicago

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                            Fi Europe 2024
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                            Medicago

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                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Medicago and GSK Announce Positive Interim Phase 2 Results for Adjuvanted Covid-19 Vaccine Candidate

                            Details : The Phase 3 portion is an event-driven, randomized, observer-blinded, crossover placebo-controlled design that will evaluate the efficacy and safety of the CoVLP formulation, compared to placebo, in up to 30,000 subjects.

                            Brand Name : CoVLP

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            May 18, 2021

                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Medicago

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                            Medicago

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                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Health Canada to Start Real-Time Review of Medicago COVID-19 Vaccine

                            Details : Medicago’s plant-derived vaccine candidate against COVID-19 uses Coronavirus-Like-Particle (CoVLP) technology with the vaccine composed of recombinant spike (S) glycoprotein expressed as virus-like-particles (VLPs) co-administered with GSK’s pandemic...

                            Brand Name : CoVLP

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            April 23, 2021

                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Medicago

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                            Medicago

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                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Brazilian Health Regulator Anvisa Authorizes Trials for GSK-Medicago COVID Vaccine

                            Details : Anvisa said the companies were authorized to conduct phase 3 trials in the country. The companies are planning to test the new vaccines in around 30,000 people, in the U.S., Canada, Europe and Latin America. Brazil may have around 3,500 volunteers for th...

                            Brand Name : Undisclosed

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            April 08, 2021

                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Medicago

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                            Medicago

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                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II/ Phase III

                            Sponsor : National Institutes of Health

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Medicago and GSK Start Phase 3 Trial of Adjuvanted Covid-19 Vaccine Candidate

                            Details : Medicago's plant-derived vaccine candidate against COVID-19 uses Coronavirus-Like-Particle (CoVLP) technology with the vaccine composed of recombinant spike (S) glycoprotein expressed as virus-like-particles (VLPs) co-administered with GSK's pandemic adj...

                            Brand Name : Undisclosed

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            March 16, 2021

                            Lead Product(s) : Recombinant Coronavirus Virus-Like Particle COVID-19 vaccine,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : National Institutes of Health

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Icahn School of Medicine

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                            Fi Europe 2024
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                            Icahn School of Medicine

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                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : CH8/1N1 LAIV,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Mount Sinai Researchers Advance a Universal Influenza Virus Vaccine

                            Details : CH8/1N1 LAIV produced a strong, functional immune response with cross-reactive antibodies targeting the hemagglutinin stalk domain, which were detectable for at least 18 months following vaccination in 65 healthy, 18 to 39-year-old US participants.

                            Brand Name : CH8/1N1 LAIV

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            December 07, 2020

                            Lead Product(s) : CH8/1N1 LAIV,AS03

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Clover Biopharmaceuticals

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                            Fi Europe 2024
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                            Clover Biopharmaceuticals

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                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Adjuvanted COVID-19 S-Trimer vaccine,AS03,CpG-1018

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II/ Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Clover Biopharmaceuticals Announces Positive Phase 1 Data for its Adjuvanted S-Trimer COVID-19 Vaccine Candida...

                            Details : Clover’s protein-based COVID-19 vaccine candidates adjuvanted with either GSK’s pandemic adjuvant system or Dynavax’s CpG 1018 plus alum induced strong neutralizing immune responses in 150 adult and elderly subjects from the Phase 1 clinical study.

                            Brand Name : SCB-2019

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            December 04, 2020

                            Lead Product(s) : Adjuvanted COVID-19 S-Trimer vaccine,AS03,CpG-1018

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : GSK

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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