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Find Clinical Drug Pipeline Developments & Deals by AsclepiX Therapeutics

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                          Top Deals by Deal Size (USD bn)

                          01

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : AXT107 (gersizangitide) is a peptide molecule that inhibits pro-angiogenic VEGFR2 and activates the Tie2 receptor, being investigated for treating retinal vascular diseases like Wet-AMD.

                          Brand Name : AXT107

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          May 06, 2024

                          Lead Product(s) : Gersizangitide

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The net proceeds will advance phase 1/2a clinical study of AXT107 (gersizangitide), which inhibits pro-angiogenic VEGFR2 and activates the vessel stabilizing receptor tyrosine kinase (Tie2), the two validated pathways for the treatment of retinal vascula...

                          Brand Name : AXT107

                          Molecule Type : Peptide

                          Upfront Cash : Undisclosed

                          July 26, 2023

                          Lead Product(s) : Gersizangitide

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Perceptive Advisors

                          Deal Size : $10.0 million

                          Deal Type : Series A Financing

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                          03

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : AXT107 is an investigational drug candidate that inhibits VEGF-A and VEGF-C and activates Tie2. With its novel mechanisms of action, AXT107 has the potential to be a standard of care monotherapy.

                          Brand Name : AXT107

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          January 05, 2021

                          Lead Product(s) : Gersizangitide

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Proceeds will be used to fund development of AXT107 for treatment of retinal diseases through Phase 1/2a clinical trials.

                          Brand Name : AXT107

                          Molecule Type : Peptide

                          Upfront Cash : $35.0 million

                          June 24, 2020

                          Lead Product(s) : Gersizangitide

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Preclinical

                          Sponsor : Perceptive Xontogeny Venture Fund

                          Deal Size : Undisclosed

                          Deal Type : Series A Financing

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