Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Gersizangitide
Therapeutic Area : Ophthalmology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
AsclepiX Completes Enrollment in DISCOVER Trial for Neovascular AMD
Details : AXT107 (gersizangitide) is a peptide molecule that inhibits pro-angiogenic VEGFR2 and activates the Tie2 receptor, being investigated for treating retinal vascular diseases like Wet-AMD.
Brand Name : AXT107
Molecule Type : Peptide
Upfront Cash : Not Applicable
May 06, 2024
Lead Product(s) : Gersizangitide
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Gersizangitide
Therapeutic Area : Ophthalmology
Study Phase : Phase I/ Phase II
Sponsor : Perceptive Advisors
Deal Size : $10.0 million
Deal Type : Series A Financing
AsclepiX Therapeutics Raises $10 Million to Advance Phase 1/2a Clinical Study of AXT107
Details : The net proceeds will advance phase 1/2a clinical study of AXT107 (gersizangitide), which inhibits pro-angiogenic VEGFR2 and activates the vessel stabilizing receptor tyrosine kinase (Tie2), the two validated pathways for the treatment of retinal vascula...
Brand Name : AXT107
Molecule Type : Peptide
Upfront Cash : Undisclosed
July 26, 2023
Lead Product(s) : Gersizangitide
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I/ Phase II
Sponsor : Perceptive Advisors
Deal Size : $10.0 million
Deal Type : Series A Financing
Lead Product(s) : Gersizangitide
Therapeutic Area : Ophthalmology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AXT107 is an investigational drug candidate that inhibits VEGF-A and VEGF-C and activates Tie2. With its novel mechanisms of action, AXT107 has the potential to be a standard of care monotherapy.
Brand Name : AXT107
Molecule Type : Peptide
Upfront Cash : Not Applicable
January 05, 2021
Lead Product(s) : Gersizangitide
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Gersizangitide
Therapeutic Area : Ophthalmology
Study Phase : Preclinical
Sponsor : Perceptive Xontogeny Venture Fund
Deal Size : Undisclosed
Deal Type : Series A Financing
AsclepiX Therapeutics Announces $35 Million Series A Financing
Details : Proceeds will be used to fund development of AXT107 for treatment of retinal diseases through Phase 1/2a clinical trials.
Brand Name : AXT107
Molecule Type : Peptide
Upfront Cash : $35.0 million
June 24, 2020
Lead Product(s) : Gersizangitide
Therapeutic Area : Ophthalmology
Highest Development Status : Preclinical
Sponsor : Perceptive Xontogeny Venture Fund
Deal Size : Undisclosed
Deal Type : Series A Financing
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