Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery
Recipient : ReviR Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
ReviR Therapeutics Reaches Milestone in Splicing Therapy Development with Asieris
Details : Asieris will be utilizing ReviR's innovative RNA modulation Platform Technologies, named BindeR and SpliceR, to identify and develop new therapeutics that target RNA to treat cancer.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 17, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery
Recipient : ReviR Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Aminolevulinic Acid Hexylester
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Asieris Announces NDA Acceptance for Regulatory Review of Cevira in China
Details : APL-1702 (cevira) is a photodynamic drug-device combination product in development for the non-surgical treatment of high-grade squamous intraepithelial lesions, licensed to Asieris by Photocure.
Brand Name : Cevira
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 12, 2024
Lead Product(s) : Aminolevulinic Acid Hexylester
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : APL-2301
Therapeutic Area : Infections and Infectious Diseases
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Asieris Pharma has announced that its product, APL-2301, has been approved for Phase I clinical trials in Australia. It is intended for treating Acinetobacter baumannii infections.
Brand Name : APL-2301
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 24, 2023
Lead Product(s) : APL-2301
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : APL-1702
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Study Phase : Phase III
Sponsor : Photocure
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Cevira (APL-1702) is a photodynamic drug-device combination product in development for the non-surgical treatment of high-grade squamous intraepithelial lesions (HSIL), licensed to Asieris by Photocure.
Brand Name : Cevira
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 20, 2023
Lead Product(s) : APL-1702
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Highest Development Status : Phase III
Sponsor : Photocure
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : APL-1401
Therapeutic Area : Gastroenterology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : APL-1401 is an oral drug got IND approval from NMPA for treatment of moderately-to-severely active ulcerative colitis, The IND application had previously been approved by the U.S. Food and Drug Administration.
Brand Name : APL-1401
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 30, 2023
Lead Product(s) : APL-1401
Therapeutic Area : Gastroenterology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery
Recipient : ReviR Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : In the agreement, Asieris will be utilizing ReviR's innovative RNA modulation Platform Technologies, named BindeR and SpliceR, to identify and develop new therapeutics (SMALL MOLECULES) that target RNA to treat cancer.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 07, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery
Recipient : ReviR Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : APL-1202,Tislelizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : APL-1202 is an orally available reversible MetAP2 Inhibitor with anti-angiogenic, anti-tumor activities and can also modulate tumor immune microenvironment. It is currently in registration clinical trials in China.
Brand Name : Vesique
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 12, 2022
Lead Product(s) : APL-1202,Tislelizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : APL-1401
Therapeutic Area : Gastroenterology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The study is a randomized, double-blind Phase Ib study evaluating the safety, tolerability, pharmacokinetics, and preliminary efficacy of APL-1401 in patients with moderate to severely active UC.
Brand Name : APL-1401
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 10, 2022
Lead Product(s) : APL-1401
Therapeutic Area : Gastroenterology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Nepicastat
Therapeutic Area : Neurology
Study Phase : Preclinical
Recipient : Acorda Therapeutics
Deal Size : $7.5 million
Deal Type : Licensing Agreement
Acorda Therapeutics Enters into License Agreement with Asieris Pharmaceuticals
Details : SYN117 (nepicastat), is a small molecule drug and the license agreement provides for its development for all non-psychiatric indications and therapeutic uses. The asset has been held by Acorda’s U.S. subsidiary, Biotie Therapies, Inc.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : $0.5 million
August 29, 2022
Lead Product(s) : Nepicastat
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Recipient : Acorda Therapeutics
Deal Size : $7.5 million
Deal Type : Licensing Agreement
Lead Product(s) : APL-1702
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : APL-1702 (trade name: Cevira®), a drug-device combination photodynamic therapy product for non-surgical treatment of cervical high-grade squamous intraepithelial lesions (HSIL) caused by any HPV subtypes.
Brand Name : Cevira
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 25, 2022
Lead Product(s) : APL-1702
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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