Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Nitroxoline
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Centers For Disease Control
Deal Size : Undisclosed
Deal Type : Agreement
Asieris, CDC Sign Agreement for APL-1202 Under Expanded Access Program
Details : Asieris has entered into an agreement to collaborate with the CDC in the US on APL-1202 (nitroxoline), It is being investigated for the treatment of FLA infections.
Product Name : APL-1202
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
January 06, 2025
Lead Product(s) : Nitroxoline
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Centers For Disease Control
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Aminolevulinic Acid Hexylester
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Asieris Announces NDA Acceptance for Regulatory Review of Cevira in China
Details : APL-1702 (cevira) is a photodynamic drug-device combination product in development for the non-surgical treatment of high-grade squamous intraepithelial lesions, licensed to Asieris by Photocure.
Product Name : Cevira
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 05, 2024
Lead Product(s) : Aminolevulinic Acid Hexylester
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : APL-2301
Therapeutic Area : Infections and Infectious Diseases
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Asieris Pharma has announced that its product, APL-2301, has been approved for Phase I clinical trials in Australia. It is intended for treating Acinetobacter baumannii infections.
Product Name : APL-2301
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 24, 2023
Lead Product(s) : APL-2301
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Aminolevulinic Acid Hexylester
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Photocure
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Cevira (APL-1702) is a photodynamic drug-device combination product in development for the non-surgical treatment of high-grade squamous intraepithelial lesions (HSIL), licensed to Asieris by Photocure.
Product Name : Cevira
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 20, 2023
Lead Product(s) : Aminolevulinic Acid Hexylester
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Photocure
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : APL-1401
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : APL-1401 is an oral drug got IND approval from NMPA for treatment of moderately-to-severely active ulcerative colitis, The IND application had previously been approved by the U.S. Food and Drug Administration.
Product Name : APL-1401
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 30, 2023
Lead Product(s) : APL-1401
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : APL-1202,Tislelizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : APL-1202 is an orally available reversible MetAP2 Inhibitor with anti-angiogenic, anti-tumor activities and can also modulate tumor immune microenvironment. It is currently in registration clinical trials in China.
Product Name : Vesique
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 12, 2022
Lead Product(s) : APL-1202,Tislelizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : APL-1401
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The study is a randomized, double-blind Phase Ib study evaluating the safety, tolerability, pharmacokinetics, and preliminary efficacy of APL-1401 in patients with moderate to severely active UC.
Product Name : APL-1401
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 11, 2022
Lead Product(s) : APL-1401
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Aminolevulinic Acid Hexylester
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : APL-1702 (trade name: Cevira®), a drug-device combination photodynamic therapy product for non-surgical treatment of cervical high-grade squamous intraepithelial lesions (HSIL) caused by any HPV subtypes.
Product Name : Cevira
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 25, 2022
Lead Product(s) : Aminolevulinic Acid Hexylester
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : APL-1202,Tislelizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Vesique (APL-1202) is a reversible and orally available MetAP2 inhibitor with anti-angiogenic and anti-tumor activities. Synergistic effects of APL-1202 and tislelizumab have been shown in various model systems of cancer including bladder cancer.
Product Name : Vesique
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 27, 2022
Lead Product(s) : APL-1202,Tislelizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : APL-1202,Tislelizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : BeiGene
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : APL-1202 is an orally available reversible MetAP2 Inhibitor with anti-angiogenic, anti-tumor activities and can also modulate tumor immune microenvironment. It is currently in Phase III/pivotal clinical trials in China, either as single agent as first-li...
Product Name : Vesique
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 13, 2021
Lead Product(s) : APL-1202,Tislelizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : BeiGene
Deal Size : Inapplicable
Deal Type : Inapplicable