[{"orgOrder":0,"company":"Aspen Pharmacare Holdings","sponsor":"Sandoz B2B","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Acquisition","leadProduct":"Lidocaine Hydrochloride","moa":"Sodium channel alpha subunits","graph1":"Neurology","graph2":"Approved","graph3":"Aspen Pharmacare Holdings","amount2":0.44,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0.44,"dosageForm":"Intravenous Injection","sponsorNew":"Aspen Pharmacare Holdings \/ Sandoz","highestDevelopmentStatusID":"12","companyTruncated":"Aspen Pharmacare Holdings \/ Sandoz"},{"orgOrder":0,"company":"Aspen Pharmacare Holdings","sponsor":"Viatris","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"","productType":"Small molecule","year":"2020","type":"Acquisition","leadProduct":"Fondaparinux Sodium","moa":"Antithrombin III","graph1":"Cardiology\/Vascular 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Find Clinical Drug Pipeline Developments & Deals by Aspen API

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Details : The agreements aim to support Aspen for commercialization of Sandostatin LAR Depot (octreotide acetate), which is indicated for long-term treatment of acromegaly & severe diarrhea and flushing episodes associated with metastatic carcinoid tumors.

                          Brand Name : Sandostatin LAR Depot

                          Molecule Type : Peptide

                          Upfront Cash : Undisclosed

                          December 04, 2023

                          Lead Product(s) : Octreotide Acetate

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Approved

                          Recipient : Sandoz B2B

                          Deal Size : $99.9 million

                          Deal Type : Agreement

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                          02

                          Details : PNEUMOSIL® (pneumococcal polysaccharide conjugate vaccine – adsorbed, 10 Valent), a well-designed vaccine, provide comparable protection by targeting the most prevalent serotypes of the bacterium causing serious illness in developing countries.

                          Brand Name : Pneumosil

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          December 12, 2022

                          Lead Product(s) : Pneumococcal Polysaccharide Conjugate Vaccine

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Approved

                          Sponsor : Gates Foundation

                          Deal Size : $30.0 million

                          Deal Type : Funding

                          Aspen API Comapny Banner

                          03

                          Details : PNEUMOSIL® (Pneumococcal Conjugate Vaccine – adsorbed, 10 Valent), a well-designed vaccine with relevant serotypes, provide comparable protection by targeting the most prevalent serotypes of the bacterium causing serious illness in developing countrie...

                          Brand Name : Pneumosil

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          August 31, 2022

                          Lead Product(s) : 10 Valent Pneumococcal Polysaccharide Conjugate Vaccine

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Approved

                          Sponsor : Serum Institute of India

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

                          Aspen API Comapny Banner

                          04

                          Details : EIKANCE (atropine sulfate monohydrate eye drops) are available on prescription for children aged 4 to 14 years, as a treatment to slow the progression of myopia and may be initiated in children when myopia progresses by 1 or more diopters per year.

                          Brand Name : Eikance

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 18, 2022

                          Lead Product(s) : Atropine Sulfate

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Aspen API Comapny Banner

                          05

                          Details : Debiopharm to enter into this new alliance with Aspen, a well-established and trusted pharmaceutical partner for the commercialization of Trelstar® in South Africa and recognize the therapeutic benefits that Trelstar® could bring to prostate cancer pat...

                          Brand Name : Trelstar

                          Molecule Type : Peptide

                          Upfront Cash : Undisclosed

                          February 01, 2022

                          Lead Product(s) : Triptorelin Pamoate

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Debiopharm

                          Deal Size : Undisclosed

                          Deal Type : Partnership

                          Aspen API Comapny Banner

                          06

                          Details : The license under discussion would enable Aspen, using COVID-19 vaccine JNJ-78436735, drug substance supplied by Johnson & Johnson, to produce Aspen-branded finished vaccine for sale to public sector markets in Africa.

                          Brand Name : JNJ-78436735

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          November 30, 2021

                          Lead Product(s) : Ad26.COV2.S

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Johnson & Johnson

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          07

                          Details : The transaction includes Trustan, Altosec, Zuvamor, Ciavor, Grantryl and Aspen Granisetron brands. To secure uninterrupted patient access to these medicines, the parties have also signed a manufacturing and supply agreement.

                          Brand Name : Trustan

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 22, 2021

                          Lead Product(s) : Esomeprazole Magnesium

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Approved

                          Sponsor : Acino Pharma

                          Deal Size : $119.4 million

                          Deal Type : Acquisition

                          Aspen API Comapny Banner

                          08

                          Details : Avion Pharmaceuticals gets exclusive rights to relaunch Cenestin® in the USA. Cenestin® is the only plant-derived mixture of nine conjugated estrogens indicated for treatment of moderate to severe symptoms of vasomotor, and vulvar and vaginal atrophy d...

                          Brand Name : Cenestin

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          November 12, 2020

                          Lead Product(s) : Conjugated Estrogens

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Approved

                          Sponsor : Avion Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Partnership

                          Aspen API Comapny Banner

                          09

                          Details : Under the terms of the agreement, Mylan Ireland Limited will acquire the commercialisation rights and related intellectual property relating to Aspen’s Thrombosis Business in Europe which includes Arixtra, Fraxiparine, Mono-Embolex and Orgaran.

                          Brand Name : Arixtra

                          Molecule Type : Small molecule

                          Upfront Cash : $310.4 million

                          September 08, 2020

                          Lead Product(s) : Fondaparinux Sodium

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved

                          Sponsor : Viatris

                          Deal Size : $757.2 million

                          Deal Type : Acquisition

                          Aspen API Comapny Banner

                          10

                          Details : The acquisition strengthens Sandoz’s presence in the hospital channel by complementing the broad Sandoz portfolio and pipeline of hospital generic and biosimilar products in Japan like Lidocaine Hydrochloride.

                          Brand Name : Lidocaine HCl-Generic

                          Molecule Type : Small molecule

                          Upfront Cash : $330.0 million

                          January 31, 2020

                          Lead Product(s) : Lidocaine Hydrochloride

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Sandoz B2B

                          Deal Size : $440.0 million

                          Deal Type : Acquisition

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