Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : ATA188
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ATA188 (Allogeneic EBV T-cell), Atara’s investigational off-the-shelf T-cell candidate, has the potential to target EBV-infected B cells and plasma cells in the central nervous system that may catalyze autoimmune responses and MS pathophysiology.
Brand Name : ATA188
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 08, 2023
Lead Product(s) : ATA188
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ATA188
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ATA188 (Allogeneic EBV T-cell), off-the-shelf T-cell candidate, has the potential to target EBV-infected B cells and plasma cells in the central nervous system that may catalyze autoimmune responses and MS pathophysiology.
Brand Name : ATA188
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
January 10, 2022
Lead Product(s) : ATA188
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : One patient with secondary progressive multiple sclerosis (SPMS) who had achieved SDI experienced a non-treatment related relapse at 18 months, occurring approximately six months after the last ATA188 dose, and elected to discontinue the study.
Brand Name : ATA188
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
October 13, 2021
Lead Product(s) : ATA188
Therapeutic Area : Immunology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ATA188, Atara’s investigational off-the-shelf T-cell candidate, has the potential to target EBV-infected B cells and plasma cells in the central nervous system that may catalyze autoimmune responses and MS pathophysiology.
Brand Name : ATA188
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
September 29, 2021
Lead Product(s) : ATA188
Therapeutic Area : Immunology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Throughout the entire Phase 1a and OLE study, nine of the 16 patients who entered the OLE demonstrated sustained disability improvement (SDI) with ATA188 treatment (seven achieved SDI in the first twelve months and two during the OLE).
Brand Name : ATA188
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 15, 2020
Details : The data indicated that ATA188 was well tolerated in all four dose cohorts; patients who achieved sustained disability improvements (SDI) time point retained it at all subsequent time points; a higher proportion of patients showed SDI with increasing dos...
Brand Name : ATA188
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
September 11, 2020
Details : Company will present for the first time 12-month data from all four cohorts in the Phase 1a study of ATA188 for the treatment of progressive forms of multiple sclerosis (MS) at MSVirtual2020: 8th Joint ACTRIMS-ECTRIMS Meeting.
Brand Name : ATA188
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
September 01, 2020
Details : Based on the Phase 1a study findings showing sustained disability improvements in active MS patients, the Phase 1b study will assess clinical outcomes including disability measures, physical and cognitive performance, biomarkers and MRI imaging, as well ...
Brand Name : ATA188
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 17, 2020
Details : Company will present updated safety and efficacy data from its ongoing Phase 1 study of ATA188 for the treatment of progressive forms of multiple sclerosis (MS) in a late-breaking e-poster presentation at the 6th European Academy of Neurology (EAN) Annua...
Brand Name : ATA188
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
May 19, 2020
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