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Hoffmann-La Roche","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody","year":"2023","type":"Collaboration","leadProduct":"AB011","moa":"||CLDN18.2","graph1":"Oncology","graph2":"Phase I","graph3":"CARsgen Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"CARsgen Therapeutics \/ F. Hoffmann-La Roche","highestDevelopmentStatusID":"6","companyTruncated":"CARsgen Therapeutics \/ F. 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                            Immune-Onc Therapeutics

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                            German Wound Congress
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                            Immune-Onc Therapeutics

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                            Lead Product(s) : IO-108,Atezolizumab,Bevacizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Immune-Onc Doses First Patient in IO-108 Phase 1b/2 Liver Cancer Study

                            Details : IO-108 antibody is being evaluated in combination with atezolizumab and bevacizumab for the treatment of locally advanced hepatocellular carcinoma.

                            Product Name : IO-108

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            February 27, 2025

                            Lead Product(s) : IO-108,Atezolizumab,Bevacizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Rznomics

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                            Rznomics

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                            Lead Product(s) : RZ-001,Atezolizumab,Valganciclovir Hydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Rznomics Inc. Liver Cancer Drug Candidate Secures Fast Track Designation

                            Details : RZ-001 is an anti-HCC activity by suppressing hTERT expression selectively in cancer cells. It is being in combination with valganciclovir for the treatment of hepatocellular carcinoma.

                            Product Name : RZ-001

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            February 17, 2025

                            Lead Product(s) : RZ-001,Atezolizumab,Valganciclovir Hydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Tempest Therapeutics

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed

                            Tempest Therapeutics

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Amezalpat,Atezolizumab,Bevacizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Tempest gets FDA Fast Track for Amezalpat in Hepatocellular Carcinoma

                            Details : TPST-1120 (amezalpat) target of PPARα, it is being investigated as a first-line treament of hepatocellular carcinoma, as a combination with atezolizumab and bevacizumab.

                            Product Name : TPST-1120

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 10, 2025

                            Lead Product(s) : Amezalpat,Atezolizumab,Bevacizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Coherus Biosciences

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                            German Wound Congress
                            Not Confirmed

                            Coherus Biosciences

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Casdozokitug,Atezolizumab,Bevacizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Coherus Presents Phase 2 Data for Casdozokitug in Hepatocellular Carcinoma

                            Details : Casdozo (casdozokitug), a selective and potent IL-27-targeting antibody, in combination with atezolizumab and bevacizumab in patients with unresectable locally advanced or metastatic HCC.

                            Product Name : Casdozo

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            January 22, 2025

                            Lead Product(s) : Casdozokitug,Atezolizumab,Bevacizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Zai Lab

                            China arrow
                            German Wound Congress
                            Not Confirmed

                            Zai Lab

                            China arrow
                            German Wound Congress
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : ZL-1310,Atezolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Zai Lab Gets Orphan Drug Designation for ZL-1310 in Small Cell Lung Cancer

                            Details : ZL-1310 is an innovative Antibody-Drug-Conjugate targeting DLL3, it is being developed as a promising therapeutic target in small cell lung cancer and other DLL3+ solid tumors.

                            Product Name : ZL-1310

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            January 22, 2025

                            Lead Product(s) : ZL-1310,Atezolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            NiKang Therapeutics

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                            German Wound Congress
                            Not Confirmed

                            NiKang Therapeutics

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : NKT2152,Atezolizumab,Bevacizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            NiKang Doses First Patient in Phase 1b/2 Study of NKT2152 for Hepatocellular Carcinoma

                            Details : NKT2152, a highly potent, selective & orally bioavailable small molecule HIF2α inhibitor, in combination with standard-of-care in the first-line treatment of patients with advanced or metastatic HCC.

                            Product Name : NKT2152

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 21, 2025

                            Lead Product(s) : NKT2152,Atezolizumab,Bevacizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Tempest Therapeutics

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed

                            Tempest Therapeutics

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Amezalpat,Atezolizumab,Bevacizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Tempest’s Amezalpat Receives FDA Orphan Drug Designation for HCC

                            Details : TPST-1120 (amezalpat) target of PPARα, it is being investigated as a first-line treament of hepatocellular carcinoma, as a combination with atezolizumab and bevacizumab.

                            Product Name : TPST-1120

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 06, 2025

                            Lead Product(s) : Amezalpat,Atezolizumab,Bevacizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Affimed

                            Germany arrow
                            German Wound Congress
                            Not Confirmed

                            Affimed

                            Germany arrow
                            German Wound Congress
                            Not Confirmed
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                            • EDQM
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                            Lead Product(s) : AFM24,Atezolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Affimed Updates On AFM24 Combo with Atezolizumab in NSCLC Therapy

                            Details : AFM24 is a tetravalent, bispecific innate cell engager that binds to CD16A. It is being evaluated for the treatment of EGFR-Wildtype Non-Small Cell Lung Cancer.

                            Product Name : AFM24

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            December 17, 2024

                            Lead Product(s) : AFM24,Atezolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Tempest Therapeutics

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed

                            Tempest Therapeutics

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Amezalpat,Atezolizumab,Bevacizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Tempest Receives FDA Approval for Amezalpat Hepatocellular Carcinoma Trial

                            Details : TPST-1120 (amezalpat) target of PPARα, it is being investigated as a first-line treament of hepatocellular carcinoma, as a combination with atezolizumab and bevacizumab.

                            Product Name : TPST-1120

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 11, 2024

                            Lead Product(s) : Amezalpat,Atezolizumab,Bevacizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Sonnet BioTherapeutics

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed

                            Sonnet BioTherapeutics

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : SON-1010,Atezolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Chardan

                            Deal Size : $3.9 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Sonnet BioTherapeutics Announces $3.9M Offering and Nasdaq Private Placement

                            Details : The net proceeds from the financing will help the company advance its lead product, SON-1010 (IL12-FHAB), for treating Platinum-resistant Ovarian Cancer.

                            Product Name : SON-1010

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            December 09, 2024

                            Lead Product(s) : SON-1010,Atezolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Chardan

                            Deal Size : $3.9 million

                            Deal Type : Public Offering

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