[{"orgOrder":0,"company":"Translational Genomics Research Institute","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Atovaquone","moa":"Cytochrome b","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Translational Genomics Research Institute","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral","sponsorNew":"Translational Genomics Research Institute \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Translational Genomics Research Institute \/ Not Applicable"},{"orgOrder":0,"company":"Quotient Sciences","sponsor":"Medicines for Malaria Venture","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Atovaquone","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Quotient Sciences","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Quotient Sciences \/ Medicines for Malaria Venture","highestDevelopmentStatusID":"12","companyTruncated":"Quotient Sciences \/ Medicines for Malaria Venture"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Atovaquone

                          Therapeutic Area : Infections and Infectious Diseases

                          Study Phase : Phase I

                          Sponsor : Medicines for Malaria Venture

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : MMV371 is a prodrug of atovaquone (selective inhibitor of cytochrome bc1 complex), ben investigated for malaria in adults.

                          Brand Name : MMV371-Prodrug

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 28, 2024

                          Lead Product(s) : Atovaquone

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Medicines for Malaria Venture

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Quotient

                          02

                          Translational Genomics Research Institute

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                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Translational Genomics Research Institute

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                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Atovaquone plus azithromycin combination was studied in other infectious disease and is expected to offer a well-tolerated option for patients infected with the novel coronavirus.

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          May 06, 2020

                          Lead Product(s) : Atovaquone,Azithromycin

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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