Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Immunome to Acquire Antibody-Related Assets and Materials from Atreca
Details : Through the acquisition, Immunome aims to utilize Atreca's APN-497444, a Glycan receptor inhibitor currently in the discovery stage, for the treatment of gastrointestinal cancers.
Brand Name : APN-497444
Molecule Type : Large molecule
Upfront Cash : $5.5 million
December 26, 2023
Lead Product(s) : APN-346958
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Xencor
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : APN-346958 targets a novel RNA-binding protein which is tumor-reactive in at least 50% of samples for six tumor types evaluated, including colorectal, thyroid, head and neck, urothelial, melanoma and brain cancer.
Brand Name : APN-346958
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 06, 2023
Lead Product(s) : APN-346958
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Xencor
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ATRC-101,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Atreca Announces Poster Presentations at Society for Immunotherapy of Cancer (SITC) Annual Meeting
Details : ATRC-101 is a monoclonal antibody derived from an antibody identified using Atreca’s discovery platform. ATRC-101 is believed to function through Driver Antigen Engagement, a novel mechanism of action in oncology.
Brand Name : ATRC-101
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 05, 2022
Lead Product(s) : ATRC-101,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Immunohistochemistry studies demonstrated tumor-selective binding of ATRC-101 to multiple non-autologous tumor tissues, and biochemical analyses indicate that it targets an extracellular, tumor-specific ribonucleoprotein (RNP) complex.
Brand Name : ATRC-101
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 04, 2022
Lead Product(s) : ATRC-301
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Zymeworks
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Atreca Announces Expansion of Preclinical Pipeline
Details : As part of the licensing agreement with Zymeworks, Atreca’s novel antibodies ATRC-301, will be conjugated using ZymeLink™, Zymeworks’ suite of proprietary cytotoxins, linkers, and conjugation technologies.
Brand Name : ATRC-301
Molecule Type : Large molecule
Upfront Cash : Undisclosed
April 05, 2022
Lead Product(s) : ATRC-301
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Zymeworks
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : APN-850271
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : APN-850271 is an IgG antibody, Currently undergoing Preclinical phase target SARS-CoV-2-binding antibodies and had neutralizing activity against replication-competent SARS-CoV-2 in an initial screen.
Brand Name : APN-850271
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 04, 2022
Lead Product(s) : APN-850271
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : ATRC-501,MAM01
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Bill & Melinda Gates Foundation
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Under the agreement, Gates MRI will lead the development of MAM01/ATRC-501 and receive commercial rights in GAVI-eligible countries located in malaria-endemic regions of the world, to advance its charitable purposes.
Brand Name : MAM01/ATRC-501
Molecule Type : Large molecule
Upfront Cash : Undisclosed
October 21, 2021
Lead Product(s) : ATRC-501,MAM01
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Bill & Melinda Gates Foundation
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Atreca Presents Initial Clinical Data from Phase 1b Trial of ATRC-101
Details : ATRC-101, which targets a novel tumor antigen and acts via a novel MOA in oncology, was well-tolerated at all doses evaluated in the study with no dose-limiting toxicities observed.
Brand Name : ATRC-101
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 29, 2021
Atreca Presentation of Initial Clinical Data from Phase 1b Trial of ATRC-101
Details : ATRC-101 has demonstrated robust anti-tumor activity as a single agent in multiple preclinical syngeneic tumor models, including one model in which PD-1 checkpoint inhibitors typically display limited activity.
Brand Name : ATRC-101
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 26, 2021
Details : Under the terms of the agreement, the companies will engage in a three-year discovery program. Atreca will provide antibodies against novel tumor targets from which Xencor will engineer XmAb bispecific antibodies that also bind to the CD3 receptor on T c...
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
July 08, 2020
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