Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
China Accepts NVK002 Drug Application for Myopia Treatment
Details : NVK002 (low-dose atropine) is a mAChR inhibitor small molecule drug, being evaluated as a potential treatment for myopia progression in children.
Product Name : NVK002
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 29, 2025
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Atropine,Pralidoxime Chloride
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved FDF
Sponsor : U.S. Department of Health and Human Services
Deal Size : $129.0 million
Deal Type : Funding
Kindeva Secures $129M SNS Contract for Nerve Agent Antidote
Details : The funding aims to advance the the manufacturing of DuoDote (atropine and pralidoxime chloride). It is indicated for the treatment of poisoning by organophosphorus nerve agents.
Product Name : Duodote
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
January 16, 2025
Lead Product(s) : Atropine,Pralidoxime Chloride
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved FDF
Sponsor : U.S. Department of Health and Human Services
Deal Size : $129.0 million
Deal Type : Funding
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Eyenovia Provides Update On Phase 3 CHAPERONE Study
Details : A drug-device combination of low-dose atropine in the Company’s Optejet dispensing platform is being investigated as a potential treatment for pediatric progressive myopia.
Product Name : Optejet
Product Type : Small molecule
Upfront Cash : Not Applicable
November 15, 2024
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Eyenovia
Deal Size : Undisclosed
Deal Type : Acquisition
Eyenovia Re-Acquires Development Rights To Micropine in U.S. and Canada
Details : Eyenovia re-acquired rights to MicroPine in the U.S. and Canada, expanding its phase III pipeline, being evaluated as a potential treatment for pediatric progressive myopia.
Product Name : MicroPine
Product Type : Small molecule
Upfront Cash : $5.0 million
January 16, 2024
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Eyenovia
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : Atropine,Pralidoxime Chloride
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved
Sponsor : ASPR
Deal Size : $9.9 million
Deal Type : Agreement
Details : Under the agreement, Meridian will supply DuoDote to the Administration for Strategic Preparedness and Response within the United States. DuoDote® is an FDA-approved dual-chamber autoinjector (atropine and pralidoxime chloride) chemical nerve agent anti...
Product Name : DuoDote
Product Type : Small molecule
Upfront Cash : Undisclosed
November 14, 2023
Lead Product(s) : Atropine,Pralidoxime Chloride
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved
Sponsor : ASPR
Deal Size : $9.9 million
Deal Type : Agreement
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NVK002 (atropine) inhibits the muscarinic actions of acetylcholine, which is investigated for anti-allergy and dry eye syndrome and progressive myopia.
Product Name : NVK002
Product Type : Small molecule
Upfront Cash : Not Applicable
October 11, 2023
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Nevakar
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NVK002 (atropine) is an investigational, preservative-free, low-dose atropine eye drop, using Vyluma’s proprietary technology to address stability, tolerability, and safety and developed for the treatment of Pediatric Myopia.
Product Name : NVK002
Product Type : Small molecule
Upfront Cash : Not Applicable
June 06, 2023
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Nevakar
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Laboratoires Thea
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NVK002 (atropine) is a proprietary, investigational, low-dose, preservative-free atropine eye drop administered nightly as a potential treatment for the progression of myopia in children.
Product Name : NVK-002
Product Type : Small molecule
Upfront Cash : Not Applicable
October 27, 2022
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Laboratoires Thea
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Nevakar
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NVK002 (atropine) is a proprietary, investigational, preservative-free eye drop administered nightly, which, if approved, would be the first-in-class pharmaceutical treatment for myopia progression in children.
Product Name : NVK002
Product Type : Small molecule
Upfront Cash : Not Applicable
September 01, 2022
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Nevakar
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Laboratoires Thea
Deal Size : $150.0 million
Deal Type : Licensing Agreement
Details : The agreement represents an expansion of the previously announced exclusive licensing agreement for the commercialization of NVK002 (having Atropine) in Europe and other select countries.
Product Name : NVK002
Product Type : Small molecule
Upfront Cash : Undisclosed
June 14, 2022
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Laboratoires Thea
Deal Size : $150.0 million
Deal Type : Licensing Agreement