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Shinyaku","highestDevelopmentStatusID":"7","companyTruncated":"Atsena Therapeutics \/ Nippon Shinyaku"},{"orgOrder":0,"company":"Atsena Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rare Diseases and Disorders","country":"U.S.A","productType":"Cell and Gene therapy","year":"2024","type":"Inapplicable","leadProduct":"ATSN-101","moa":"||LCA1","graph1":"Rare Diseases and Disorders","graph2":"Phase I\/ Phase II","graph3":"Atsena Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Subretinal Injection","sponsorNew":"Atsena Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Atsena Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Atsena Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rare Diseases and Disorders","country":"U.S.A","productType":"Cell and Gene 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Find Clinical Drug Pipeline Developments & Deals by Atsena Therapeutics

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                          Top Deals by Deal Size (USD bn)

                          01

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : The proceeds from the financing will be used to advance Atsena’s lead program, ATSN-201, for the treatment of X-linked retinoschisis (XLRS).

                          Product Name : ATSN-201

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          April 02, 2025

                          Lead Product(s) : ATSN-201

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Bain Capital

                          Deal Size : $150.0 million

                          Deal Type : Series C Financing

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                          02

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : ATSN-201 is an investigational gene therapy that leverages one of the company’s novel spreading capsids, AAV.SPR, it is being developed for the treatment of X-linked retinoschisis (XLRS).

                          Product Name : ATSN-201

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          March 12, 2025

                          Lead Product(s) : ATSN-201

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : ATSN-201 is an investigational gene therapy that leverages one of the company’s novel spreading capsids, AAV.SPR, it is being developed for the treatment of X-linked retinoschisis (XLRS).

                          Product Name : ATSN-201

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          January 08, 2025

                          Lead Product(s) : ATSN-201

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Nippon Shinyaku will receive exclusive commercial rights of ATSN-101, a first-in-class, investigational gene therapy for the treatment of LCA1, in the U.S. and Japan.

                          Product Name : ATSN-101

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          November 13, 2024

                          Lead Product(s) : ATSN-101

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Nippon Shinyaku

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          05

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : ATSN-201 utilizes AAV.SPR, the company’s novel spreading capsid, to achieve therapeutic levels of gene expression. It is being evaluated for the treatment of X-linked Retinoschisis.

                          Product Name : ATSN-201

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          September 17, 2024

                          Lead Product(s) : ATSN-201

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : ATSN-201 utilizes AAV.SPR, the company’s novel spreading capsid, to achieve therapeutic levels of gene expression. It is being evaluated for the treatment of X-linked Retinoschisis.

                          Product Name : ATSN-201

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          August 14, 2024

                          Lead Product(s) : ATSN-201

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : ATSN-201 is an investigational gene therapy that leverages one of the company’s novel spreading capsids, AAV.SPR, it is being developed for the treatment of X-linked retinoschisis (XLRS).

                          Product Name : ATSN-201

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          March 13, 2024

                          Lead Product(s) : ATSN-201

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : SAR439483 (ATSN-101) is a novel GUCY2D modulator which is currently being evaluated in phase 1/2 clinical development for the treatment of GUCY2D-associated leber congenital amaurosis (LCA1).

                          Product Name : ATSN-101

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          January 16, 2024

                          Lead Product(s) : ATSN-101,Prednisone,Triamcinolone

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : ATSN-201 utilizes AAV.SPR, a novel spreading capsid, to achieve therapeutic gene expression in central retina photoreceptors, being evaluated for X-linked Retinoschisis.

                          Product Name : ATSN-201

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          January 05, 2024

                          Lead Product(s) : ATSN-201

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : ATSN-101, gene therapy for patients with Leber congenital amaurosis caused by biallelic mutations in GUCY2D (LCA1). RMAT designation was granted based on positive 6-month efficacy data from the company’s ongoing Phase I/II clinical trial of ATSN-101.

                          Product Name : ATSN-101

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          November 14, 2023

                          Lead Product(s) : ATSN-101

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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