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    [{"orgOrder":0,"company":"Avalo Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"MDGN-002","moa":"LIGHT","graph1":"Gastroenterology","graph2":"Phase I","graph3":"Avalo Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Avalo Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Avalo Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Avalo Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"AVTX-002","moa":"LIGHT","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase II","graph3":"Avalo 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Therapeutics"},{"orgOrder":0,"company":"Avalo Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"L-Fucose","moa":"","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Avalo Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Powder","sponsorNew":"Avalo Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Avalo Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Avalo Therapeutics","sponsor":"ES Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"","productType":"Large molecule","year":"2022","type":"Agreement","leadProduct":"AVTX-007","moa":"LIGHT","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase II","graph3":"Avalo Therapeutics","amount2":0.01,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0.01,"dosageForm":"Injectable\/Injection","sponsorNew":"Avalo Therapeutics \/ ES Therapeutics","highestDevelopmentStatusID":"8","companyTruncated":"Avalo Therapeutics \/ ES Therapeutics"},{"orgOrder":0,"company":"Avalo Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"","productType":"Large molecule","year":"2023","type":"Not Applicable","leadProduct":"Monoclonal Antibody","moa":"","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase II","graph3":"Avalo Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Avalo Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Avalo Therapeutics \/ Not 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Diseases","graph2":"Phase II","graph3":"Avalo Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Avalo Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Avalo Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Avalo Therapeutics","sponsor":"AUG Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"","productType":"Small molecule","year":"2023","type":"Divestment","leadProduct":"Alpha-D-Galactose","moa":"","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Avalo Therapeutics","amount2":0.050000000000000003,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0.050000000000000003,"dosageForm":"","sponsorNew":"Avalo Therapeutics \/ AUG Therapeutics","highestDevelopmentStatusID":"8","companyTruncated":"Avalo Therapeutics \/ AUG Therapeutics"},{"orgOrder":0,"company":"Avalo Therapeutics","sponsor":"Avalo Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Acquisition","leadProduct":"AVTX-009","moa":"","graph1":"Dermatology","graph2":"Phase I","graph3":"Avalo Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"","sponsorNew":"Avalo Therapeutics \/ Avalo Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"Avalo Therapeutics \/ Avalo Therapeutics"},{"orgOrder":0,"company":"Avalo Therapeutics","sponsor":"Commodore Capital","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"","productType":"Large molecule","year":"2024","type":"Private Placement","leadProduct":"AVTX-009","moa":"","graph1":"Dermatology","graph2":"Phase I","graph3":"Avalo Therapeutics","amount2":0.19,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Dermatology","amount2New":0.19,"dosageForm":"","sponsorNew":"Avalo Therapeutics \/ Commodore Capital","highestDevelopmentStatusID":"6","companyTruncated":"Avalo Therapeutics \/ Commodore Capital"},{"orgOrder":0,"company":"Avalo Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"AVTX-009","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Avalo Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Avalo Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"Avalo Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Avalo Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"AVTX-009","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Avalo Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Avalo Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"Avalo Therapeutics \/ Not Applicable"}]

    Find Clinical Drug Pipeline Developments & Deals by Avalo Therapeutics

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                            01

                            Avalo Therapeutics

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                            Avalo Therapeutics

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                            Lead Product(s) : AVTX-009

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Avalo Doses First Patient in AVTX-009 Phase 2 LOTUS Trial For Hidradenitis

                            Details : AVTX-009 is a humanized monoclonal antibody (IgG4) that binds to interleukin-1 beta, being developed for moderate to severe hidradenitis suppurativa.

                            Brand Name : AVTX-009

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 08, 2024

                            Lead Product(s) : AVTX-009

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Avalo Therapeutics

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                            Medlab Asia & Asia Health
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                            Avalo Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : AVTX-009

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Avalo Therapeutics Gets Active IND for AVTX-009 in Hidradenitis Suppurativa

                            Details : AVTX-009 is a humanized monoclonal antibody (IgG4) that binds to interleukin-1 beta, being developed for moderate to severe hidradenitis suppurativa.

                            Brand Name : AVTX-009

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            July 09, 2024

                            Lead Product(s) : AVTX-009

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Avalo Therapeutics

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                            Medlab Asia & Asia Health
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                            Avalo Therapeutics

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                            Lead Product(s) : AVTX-009

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I

                            Recipient : AlmataBio

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Avalo Acquires Anti-IL-1β mAb and Announces Up to $185 Million Private Placement

                            Details : Through the acquisition of AlmataBio, Avalo acquires Phase 2-ready, AVTX-009, a humanized monoclonal antibody (IgG4) that binds to interleukin-1β, being developed for hidradenitis suppurativa.

                            Brand Name : AVTX-009

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            March 27, 2024

                            Lead Product(s) : AVTX-009

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I

                            Recipient : AlmataBio

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            04

                            Avalo Therapeutics

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            Avalo Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : AVTX-009

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I

                            Sponsor : Commodore Capital

                            Deal Size : $185.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Avalo Acquires Anti-IL-1β mAb and Announces Financing of up to $185 Million

                            Details : The net proceeds will be used for the developement of AVTX-009, a humanized monoclonal antibody (IgG4) that binds to interleukin-1β, being developed for hidradenitis suppurativa.

                            Brand Name : AVTX-009

                            Molecule Type : Large molecule

                            Upfront Cash : $115.6 million

                            March 27, 2024

                            Lead Product(s) : AVTX-009

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I

                            Sponsor : Commodore Capital

                            Deal Size : $185.0 million

                            Deal Type : Private Placement

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                            05

                            Avalo Therapeutics

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            Avalo Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : Alpha-D-Galactose

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : AUG Therapeutics

                            Deal Size : $45.1 million

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            Avalo Enters into Agreement to Divest AVTX-800 Series

                            Details : Under the divestiture, AUG gains rights, title and interest in, assets relating to AVTX-801 (D-galactose), AVTX-802 (D-mannose) and AVTX-803 (L-fucose). AVTX-801 is a therapeutic dose of D-galactose currently in development for the treatment of phosphogl...

                            Brand Name : AVTX-801

                            Molecule Type : Small molecule

                            Upfront Cash : $0.1 million

                            September 12, 2023

                            Lead Product(s) : Alpha-D-Galactose

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : AUG Therapeutics

                            Deal Size : $45.1 million

                            Deal Type : Divestment

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                            06

                            Avalo Therapeutics

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            Avalo Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : Quisovalimab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Avalo Announces Topline Data from Phase 2 PEAK Trial for AVTX-002 (quisovalimab) in Patients with Non-Eosinoph...

                            Details : AVTX-002 (quisovalimab) is a fully human monoclonal antibody (mAb), directed against human LIGHT, and investigated for the treatment of patients with poorly controlled non-eosinophilic asthma

                            Brand Name : AVTX-002

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 26, 2023

                            Lead Product(s) : Quisovalimab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Avalo Therapeutics

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            Avalo Therapeutics

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                            Medlab Asia & Asia Health
                            Not Confirmed
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                            Lead Product(s) : AVTX-002

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase II

                            Sponsor : SVB Securities

                            Deal Size : $15.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Avalo Therapeutics, Inc. Announces Pricing of $15 Million Public Offering of Common Stock and Warrants

                            Details : AVTX-002 is a fully human monoclonal antibody, directed against human LIGHT. AVTX-002 is currently in Phase 2 development for non-eosinophilic asthma (NEA) with proof-of-concept data in inflammatory bowel diseases (IBD) and COVID-19 acute respiratory dis...

                            Brand Name : AVTX-002

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            February 02, 2023

                            Lead Product(s) : AVTX-002

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase II

                            Sponsor : SVB Securities

                            Deal Size : $15.0 million

                            Deal Type : Public Offering

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                            08

                            Avalo Therapeutics

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            Avalo Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : Monoclonal Antibody

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Avalo Announces it Has Completed Targeted Enrollment of 80 Patients in Phase 2 PEAK Trial of AVTX-002 in Non-E...

                            Details : AVTX-002 is a fully human monoclonal antibody (mAb), directed against human LIGHT (Lymphotoxin-like, exhibits Inducible expression, and competes with Herpes Virus Glycoprotein D for Herpesvirus Entry Mediator (HVEM), a receptor expressed by T lymphocytes...

                            Brand Name : AVTX-002

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            January 17, 2023

                            Lead Product(s) : Monoclonal Antibody

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Avalo Therapeutics

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            Avalo Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : AVTX-007

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase II

                            Sponsor : ES Therapeutics

                            Deal Size : $5.0 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Avalo Sells Economic Rights to Previously Out-Licensed Assets for $5 Million

                            Details : AVTX-007 is a fully human monoclonal antibody for the treatment of Still’s Disease, including adult-onset Still’s disease (AOSD) and systemic juvenile jdiopathic Arthritis (SJIA).

                            Brand Name : AVTX-007

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            November 07, 2022

                            Lead Product(s) : AVTX-007

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase II

                            Sponsor : ES Therapeutics

                            Deal Size : $5.0 million

                            Deal Type : Agreement

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                            10

                            Avalo Therapeutics

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            Avalo Therapeutics

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : L-Fucose

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Avalo Therapeutics Announces First Patient Dosed in the AVTX-803 Pivotal Trial (LADDER) for the Treatment of L...

                            Details : The active pharmaceutical ingredient (API) in AVTX-803 is L-fucose an oral formulation of L-fucose that enhances fucosylation of proteins in the absence of a functioning GDP-fucose transporter, partially restoring protein function.

                            Brand Name : AVTX-803

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 02, 2022

                            Lead Product(s) : L-Fucose

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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