Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : TROP2-TRACTr based therapeutics
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Janux Therapeutics
Deal Size : $56.0 million
Deal Type : Series A Financing
Details : The financing will be used to advance the Company’s preclinical pipeline, including a TROP2-TRACTr and PSMA-TRACTr, with expected advancement of the Company’s first candidate into the clinic in the first half of next year.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
March 03, 2021
Lead Product(s) : TROP2-TRACTr based therapeutics
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Janux Therapeutics
Deal Size : $56.0 million
Deal Type : Series A Financing
Details : Avalon is expanding its AVA-001 clinical trial to recruit patients with relapsed/refractory Non-Hodgkin lymphoma (R/R-NHL).
Brand Name : AVA-001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
October 01, 2020
Lead Product(s) : AVA-001,Fludarabine Phosphate,Cyclophosphamide
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Completed Phase I Clinical Study of 4-1BB Based Anti-CD19 CAR-T Therapy for Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia; Achieved 90% Complete Remission (CR) Rate with Minimum Toxicity or Adverse Side Effects.
Brand Name : AVA-001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
July 13, 2020
Lead Product(s) : AVA-001,Fludarabine Phosphate,Cyclophosphamide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : AVA-001,Fludarabine Phosphate,Cyclophosphamide
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Nine out of ten patients with relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL) have achieved complete remission (CR rate of 90%) within one month after the initiation of AVA-001 CAR T-cell therapy treatment.
Brand Name : AVA-001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 29, 2020
Lead Product(s) : AVA-001,Fludarabine Phosphate,Cyclophosphamide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : S-layer COVID vaccine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Undisclosed
Sponsor : University of Natural Resources
Deal Size : Undisclosed
Deal Type : Partnership
Avalon GloboCare to Develop Intranasal and Oral Covid-19 Vaccine
Details : Avalon forms strategic partnership with the University of Natural Resources and Life Sciences (BOKU) in Vienna, Austria and the nanotechnology laboratory of Professor Uwe B. Sleytr on a novel S-layer SARS-CoV-2 (COVID-19) vaccine.
Brand Name : Undisclosed
Molecule Type : Vaccine
Upfront Cash : Undisclosed
June 25, 2020
Lead Product(s) : S-layer COVID vaccine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Undisclosed
Sponsor : University of Natural Resources
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : AVA-Trap
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Avalon’s AVA-Trap™ therapeutic program is currently entering animal model testing followed by expedited clinical studies with the goal of providing an effective therapeutic option to combat COVID-19.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 20, 2020
Lead Product(s) : AVA-Trap
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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