[{"orgOrder":0,"company":"Avance Clinical","sponsor":"Atossa Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"AUSTRALIA","productType":"Undisclosed","year":"2020","type":"Collaboration","leadProduct":"AT-301","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"Avance Clinical","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Nasal Spray","sponsorNew":"Avance Clinical \/ Atossa Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"Avance Clinical \/ Atossa Therapeutics"},{"orgOrder":0,"company":"Avance Clinical","sponsor":"Odyssey Health","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"PRV-002","moa":"","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase I","graph3":"Avance Clinical","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Spray","sponsorNew":"Avance Clinical \/ Avance Clinical","highestDevelopmentStatusID":"6","companyTruncated":"Avance Clinical \/ Avance Clinical"},{"orgOrder":0,"company":"Avance Clinical","sponsor":"Enveric Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Agreement","leadProduct":"EB-373","moa":"","graph1":"Psychiatry\/Psychology","graph2":"IND Enabling","graph3":"Avance Clinical","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"","sponsorNew":"Avance Clinical \/ Avance Clinical","highestDevelopmentStatusID":"5","companyTruncated":"Avance Clinical \/ Avance Clinical"},{"orgOrder":0,"company":"Avance Clinical","sponsor":"Oragenics","pharmaFlowCategory":"D","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Partnership","leadProduct":"ONP-002","moa":"","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase I","graph3":"Avance Clinical","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Spray","sponsorNew":"Avance Clinical \/ Avance Clinical","highestDevelopmentStatusID":"6","companyTruncated":"Avance Clinical \/ Avance Clinical"}]

Find Clinical Drug Pipeline Developments & Deals by Avance Clinical

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The partnership aims to evaluate Oragenics' lead drug candidate, ONP-002, a NCE delivered through a unique intranasal device, for mild Traumatic Brain Injury.

                          Brand Name : PRV-002

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          May 07, 2024

                          Lead Product(s) : ONP-002

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase I

                          Recipient : Oragenics

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          02

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Under the agreement, Avance Clinical will manage the Phase 1 clinical trial of EB-373 in coordination with Enveric. EB-373 is designed as a next-generation proprietary psilocin prodrug and developed leveraging its Psybrary™ drug discovery platform to t...

                          Brand Name : EB-373

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          March 23, 2023

                          Lead Product(s) : EB-373

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Preclinical

                          Recipient : Enveric Biosciences

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          03

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : No severe adverse events were noted as PRV-002 was well-tolerated for all cohorts. No delays were instituted between cohorts. Vital signs, EKG readings, sleep patterns and breathing function were all normal through the entirety of the study.

                          Brand Name : PRV-002

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 28, 2022

                          Lead Product(s) : PRV-002

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase I

                          Recipient : Odyssey Health

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The study is a double-blinded, randomized, and placebo-controlled safety study of AT-301 nasal spray in 32 healthy adult subjects divided into two study groups.

                          Brand Name : AT-301

                          Molecule Type : Undisclosed

                          Upfront Cash : Undisclosed

                          July 22, 2020

                          Lead Product(s) : AT-301

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : Atossa Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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