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[{"orgOrder":0,"company":"Avanzanite Bioscience","sponsor":"SIFI","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"Sifi Announces License Agreement with Avanzanite Bioscience for Akantior\u00ae","therapeuticArea":"Infections and Infectious Diseases","highestDevelopmentStatus":"Preclinical","country":"NETHERLANDS","productType":"Small molecule","productStatus":"Approved","date":"January 2023","url1":"","url2":"","graph1":"Infections and Infectious Diseases","graph2":"Preclinical"},{"orgOrder":0,"company":"Avanzanite Bioscience","sponsor":"Advicenne","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"Avanzanite Bioscience Partners With Advicenne to Commercialize Sibnayal\u00ae For the Treatment of Rare Kidney Disease in Germany, Austria, Switzerland and Greece","therapeuticArea":"Nephrology","highestDevelopmentStatus":"Phase IV","country":"NETHERLANDS","productType":"Small molecule","productStatus":"Approved","date":"February 2023","url1":"","url2":"","graph1":"Nephrology","graph2":"Phase IV"},{"orgOrder":0,"company":"Avanzanite Bioscience","sponsor":"Advicenne","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"Avanzanite Bioscience Expands Partnership with Advicenne in Additional European Countries","therapeuticArea":"Nephrology","highestDevelopmentStatus":"Phase IV","country":"NETHERLANDS","productType":"Small molecule","productStatus":"Approved","date":"October 2023","url1":"","url2":"","graph1":"Nephrology","graph2":"Phase IV"}]

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            Details:

            Under the partnership, Avanzanite gains commercialization and distribution rights into three additional European countries, for Sibnayal (potassium citrate and potassium bicarbonate), the first approved medicinal product in Europe for distal Renal Tubular Acidosis.

            Lead Product(s): Potassium Citrate,Potassium hydrogen carbonate

            Therapeutic Area: Nephrology Product Name: Sibnayal

            Highest Development Status: Phase IV Product Type: Small molecule

            Partner/Sponsor/Collaborator: Advicenne

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Partnership October 18, 2023

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            Sibnayal (potassium citrate) is a medicine used to treat patients from the age of one year with distal renal tubular acidosis (dRTA), a disease in which the kidneys do not remove acid through the urine well enough.

            Lead Product(s): Potassium Citrate,Potassium hydrogen carbonate

            Therapeutic Area: Nephrology Product Name: Sibnayal

            Highest Development Status: Phase IV Product Type: Small molecule

            Partner/Sponsor/Collaborator: Advicenne

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Agreement February 28, 2023

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            AKANTIOR® (polihexanide) is an investigational anti-amoebic polymer that has been granted Orphan Drug Designation by both the European Medicines Agency ("EMA") and Food and Drug Administration ("FDA") for AK.

            Lead Product(s): Polyhexanide

            Therapeutic Area: Infections and Infectious Diseases Product Name: Akantior

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: SIFI

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Licensing Agreement January 10, 2023

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