[{"orgOrder":0,"company":"Avirmax","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Not Applicable","leadProduct":"rAAV-based Gene Therapy","moa":"","graph1":"Ophthalmology","graph2":"Preclinical","graph3":"Avirmax","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Avirmax \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"Avirmax \/ Not Applicable"},{"orgOrder":0,"company":"Avirmax","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2025","type":"Inapplicable","leadProduct":"ABI-110","moa":"","graph1":"Ophthalmology","graph2":"Phase I\/ Phase II","graph3":"Avirmax","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Avirmax \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Avirmax \/ Inapplicable"},{"orgOrder":0,"company":"Avirmax","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2025","type":"Inapplicable","leadProduct":"ABI-201","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"IND Enabling","graph3":"Avirmax","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Avirmax \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Avirmax \/ Inapplicable"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pittcon 2025
                          Not Confirmed
                          Pittcon 2025
                          Not Confirmed

                          Details : ABI-201 utilizes Avirmax's proprietarily engineered capsid, AAV.N54, to efficiently deliver therapeutic transgenes to macular retina. It is being evaluated for dry age-related macular degeneration.

                          Product Name : ABI-201

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          February 28, 2025

                          Lead Product(s) : ABI-201

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Pittcon 2025
                          Not Confirmed
                          Pittcon 2025
                          Not Confirmed

                          Details : ABI-110 utilizes AAV.N54 capsid, to efficiently deliver therapeutic transgene to the macular retina. It is being evaluated for the treatment of wet age-related macular degeneration including PCV.

                          Product Name : ABI-110

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          February 03, 2025

                          Lead Product(s) : ABI-110

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Pittcon 2025
                          Not Confirmed
                          Pittcon 2025
                          Not Confirmed

                          Details : ACI’s rBV-Sf9-AAV platform is based on single use technology, utilizes suspension cell culture free of fetal bovine serum and uses non-animal derived material throughout the manufacturing process.

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          December 15, 2022

                          Lead Product(s) : rAAV-based Gene Therapy

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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