Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AVM0703 is small molecule immunomodulatory drug enrolling Phase 2 trials in US in relapsed/refractory Non-Hodgkin's Lymphoma (NHL) which began enrollment Q3 2023 (partially funded by NCI Ph II FastTrak grant 1R44CA272096).
Product Name : AVM0703
Product Type : Steroid
Upfront Cash : Inapplicable
January 08, 2023
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : The Division of Cancer Treatment and Diagnosis
Deal Size : $2.0 million
Deal Type : Funding
Details : AVM0703 (Dexamethasone sodium phosphate) is a small molecule which triggers the production and release of endogenous bispecific gamma delta TCR+ invariant TCR+ Natural Killer T-like cells (AVM-NKT).
Product Name : AVM0703
Product Type : Steroid
Upfront Cash : Undisclosed
June 14, 2022
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : The Division of Cancer Treatment and Diagnosis
Deal Size : $2.0 million
Deal Type : Funding
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Endocrinology
Study Phase : Preclinical
Sponsor : National Institute of Diabetes and Digestive Kidney Disease
Deal Size : $1.6 million
Deal Type : Funding
Details : T1D is an autoimmune disease that destroys beta cells, the insulin-making cells in the pancreas. This award provides an endorsement of AVM0703’s potential in two distinct and crucial therapeutic areas, diabetes and cancer.
Product Name : AVM0703
Product Type : Steroid
Upfront Cash : Undisclosed
May 04, 2022
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Endocrinology
Highest Development Status : Preclinical
Sponsor : National Institute of Diabetes and Digestive Kidney Disease
Deal Size : $1.6 million
Deal Type : Funding
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AVM0703 is a small molecule which triggers the production and release of endogenous bispecific gamma delta TCR+ and invariant TCR+ Natural Killer T-like cells (AVM-NKT).
Product Name : AVM0703
Product Type : Steroid
Upfront Cash : Inapplicable
April 19, 2022
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AVM0703 (dexamethasone) led to, complete response in 27% of immune-resistant mouse A20 tumors as monotherapy and complete response in 60% when combined with 2 doses of cyclophosphamide/fludarabine (CyFlu).
Product Name : AVM0703
Product Type : Steroid
Upfront Cash : Inapplicable
January 06, 2022
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Dexamethasone Sodium Phosphate,Hydrocortisone,Undisclosed
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
AVM Biotechnology Awarded SBIR Phase I Grant from National Cancer Institute
Details : AVM Biotechnology has been awarded a National Cancer Institute Small Business Innovation Research Grant from the NIH to study the use of AVM0703 as a preconditioning agent to allow safe and efficient delivery of therapeutic immune cells for cancer treatm...
Product Name : AVM0703
Product Type : Steroid
Upfront Cash : Inapplicable
November 06, 2020
Lead Product(s) : Dexamethasone Sodium Phosphate,Hydrocortisone,Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Seattle AVM Biotechnology Announces Second IND for AVM0703
Details : This second study will evaluate AVM0703 in two different ARDS patient populations: one with COVID-19-mediated moderate to severe ARDS and the other with Influenza-mediated severe ARDS.
Product Name : AVM0703
Product Type : Steroid
Upfront Cash : Inapplicable
September 16, 2020
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
AVM Biotechnology has FDA Approval for Clinical Trials for Promising New Cancer Treatment
Details : AVM Biotechnology received clinical trial approval for AVM0703. Unlike chemotherapy and radiation, AVM0703 spares platelets and red blood cells, limiting the need for transfusions.
Product Name : AVM0703
Product Type : Steroid
Upfront Cash : Inapplicable
April 14, 2020
Lead Product(s) : Dexamethasone Sodium Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable